Category Archives: Pharmacological Treatments

Antipsychotic Drugs in Dementia: Best Practice Guide (RCN)

Posted on May 23, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

Summary This “Antipsychotic drugs in dementia: a best practice guide” booklet, has been published by the Royal College of Nursing (RCN), with support from the Department of Health. The main content headings comprise: What is dementia? Behavioural and psychological symptoms … Continue reading →

Posted in Acute Hospitals, Antipsychotics, Community Care, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), Management of Condition, National, NHS, Non-Pharmacological Treatments, Pharmacological Treatments, Practical Advice, Proposed for Next Newsletter, Quick Insights, RCN, UK, Universal Interest | Tagged Aggression, Aggressive Behaviour, Agitation, Antipsychotics, Apathy / Indifference, Assess, Atypical Antipsychotics, Behavioral and Psychological Symptoms of Dementia (BPSD), BPSD: Behavioral and Psychological Symptoms of Dementia, Delusions, Four Seasons Health Care, Hallucinations, Hallucinations in People with Dementia, History of Antipsychotic Use in Dementia, Inappropriate Sexual Behaviour, Misidentifications, Neuroleptics, Paranoid Ideas, PEARL (Positively Enriching And Enhancing Residents’ Lives) Project, Professor Alistair Burns, Professor Sube Banerjee, Psychological Symptoms of Dementia (BPSD), Psychosis, Reduplications, Review (STAR) Initiative, Sleeping, Stop, Think, Wandering | Leave a comment

Automated Pill Dispenser Project Evaluation (Improvement and Efficiency West Midlands)

Posted on April 23, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 10, May 2012]. Summary This end of project evaluation report, from Improvement and Efficiency West Midlands, covers the PivoTell automated pill dispenser. Mark 3 … Continue reading →

Posted in Assistive Technology, Community Care, For Social Workers (mostly), Local Interest, Management of Condition, National, NHS, Non-Pharmacological Treatments, Pharmacological Treatments, Practical Advice, Quick Insights, Telecare, Telehealth, UK, Universal Interest, Wolverhampton | Tagged ADASS, Adult Social Care and Inclusion: Walsall MBC, Alliance Boots, Assessment Flowchart, Automated Pill Dispenser Project, Automatic Medicine Dispensers, Business Case, Care Services Improvement Partnership (CSIP), Charter & Plan Ltd, Community Pharmacies, Compliance Aids, Cost Analysis, Coventry City Council, Directors of Adult Social Services in the West Midlands (ADASS), Dudley Metropolitan Borough Council, Health Services Management Centre: University of Birmingham, Herefordshire County Council, Improvement and Efficiency West Midlands, Local Authorities, Medication Management Leads, Murray’s Healthcare, NHS West Midlands, North East Essex PCT, PCT Clusters, PCT Telecare Leads, Pharmacy Services: Community, PivoTell, PivoTell Automated Pill Dispenser Mk 3, Prescriptions Dispensed in the Community, Prevention and Early Intervention (ADASS), Primary Care Trusts in the West Midlands, Regional Improvement and Efficiency Partnership (IEP), Right Pills at the Right Time, Simon Adams Consulting Ltd, Staffordshire County Council, Staffordshire North PCT, Telford and Wrekin Council, University of Birmingham, West Midlands, West Midlands ADASS Telehealthcare Network, West Midlands Regional ADASS Telehealthcare Network, West Midlands SHA, Wolverhampton City Council, Worcestershire County Council | Leave a comment

Johnson & Johnson Fined $1.1bn Over Risperdal: Subversion of Science? (BBC Health News)

Posted on April 13, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

Summary The drugs giant Johnson & Johnson (J&J) has been ordered by a US judge to pay $1.1bn (£690m) for downplaying the risks involved in taking its anti-psychotic drug Risperdal (Risperidone). This is only the latest of fines the company … Continue reading →

Posted in Antipsychotics, BBC News, In the News, International, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics in Elderly People with Dementia, Atypical Antipsychotics, BBC Health News, Prescribing Anti-Psychotic Drugs to People with Dementia | Leave a comment

Cholinesterase Inhibitors for Dementia with Lewy Bodies, Parkinson’s Disease Dementia and Cognitive Impairment in Parkinson’s Disease (Cochrane Library)

Posted on April 4, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 9, April 2012]. Summary Earlier Cochrane reviews have examined the use of cholinesterase inhibitors in both Parkinson’s Disease with dementia (PDD) and dementia with … Continue reading →

Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Researchers (mostly), Pharmacological Treatments, Systematic Reviews, Universal Interest | Tagged Acetylcholine, ADCS (Scale), ALOIS: the Cochrane Dementia and Cognitive Improvement Group, Behavioural Disturbance Rating Scales, Cholinesterase Inhibitors, CIND-PD: Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease (CIND-PD), Dementia with Lewy Bodies, DLB: Dementia with Lewy Bodies, Donepezil, Donepezil (Aricept, John Radcliffe Hospital, Mini Mental State Examination (MMSE), Oxford University Hospitals NHS Trust, Parkinson’s Disease Dementia, Parkinsonian Symptoms, PDD: Parkinson's Disease with Dementia, Rivastigmine, Unified Parkinson's Disease Rating Scale (UPDRS) | Leave a comment

Discontinuation of Antidepressants in People with Dementia and Neuropsychiatric Symptoms (DESEP Study) (BMJ)

Posted on March 21, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 9, April 2012]. Summary Roughly 80% of nursing home residents have dementia in Norway. 90% have neuropsychiatric symptoms. Roughly 40% of residents in Norwegian … Continue reading →

Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments | Tagged Antidepressants, Antidepressants for Depression in Dementia (HTA-SADD), Centre for Old Age Psychiatric Research (Innlandet Hospital Trust), Citalopram, Clinical Dementia Rating Scale, Cornell Scale for Depression in Dementia (CSDD), Depression, Depression / Dysphoria, Depression in Older People, Depressive Symptoms, DESEP Study, Escitalopram, Innlandet Hospital Trust (Ottestad; Norway), Lawton and Brody’s Physical Self Maintenance Scale, Neuropsychiatric Inventory (NPI), Neuropsychiatric Inventory Scale, Neuropsychiatric Inventory-Nursing Home version (NPI-NH), Neuropsychiatric Symptoms, Norway, Norwegian Centre for Dementia Research, Nursing Home Residents with Dementia, Nursing Home Residents with Dementia (in Norway), Nursing Homes, Paroxetine, Quality of Life-Alzheimer’s Disease Scale, Selective Serotonin Reuptake Inhibitors (SSRIs), Sertraline, Severe Impairment Battery, SSRIs: Selective Serotonin Reuptake Inhibitors, Unified Parkinson’s Disease Rating Scale, University Hospital (Oslo) | Leave a comment

Donepezil and Memantine for Moderate-to-Severe Alzheimer’s Disease (NEJM / BBC News)

Posted on March 9, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 8, March 2012]. Summary A study was performed by researchers at King’s College London, to see whether the benefits of cholinesterase inhibitors for the … Continue reading →

Posted in Acute Hospitals, BBC News, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, NHS, Pharmacological Treatments, Practical Advice, Quick Insights, UK, Universal Interest | Tagged Alzheimer's Society, Aricept, Bristol Activities of Daily Living Scale (BADLS), Donepezil, Ebixa, Institute of Psychiatry: King's College London, Medical Research Council, Memantine, Moderate-to-Severe Alzheimer's Disease, Standardized Mini-Mental State Examination: SMMSE | Leave a comment

Aspirin, Steroidal and Non-Steroidal Anti-Inflammatory Drugs for Alzheimer’s Disease?

Posted on March 6, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 8, March 2012]. Summary Inflammatory processes have previously been thought to play a role in the pathogenesis of Alzheimer’s Disease (AD). The authors of … Continue reading →

Posted in For Researchers (mostly), International, Pharmacological Treatments | Tagged Aceclofenac, Acemetacin, ALOIS: the Cochrane Dementia and Cognitive Improvement Group, Anti-Inflammatory, Aspirin, Bangkok and Baycrest Centre for Geriatric Care, Betamethasone, Celecoxib, Cortisone, COX-2 Inhibitors, Cyclooxygenase 2 Inhibitor, Deflazacort, Department of Family Medicine: Ramathibodi Hospital, Dexamethasone, Dexibruprofen, Dexketoprofen, Diclofenac Sodium, Diflunisal, Diflusinal, Etodolac, Etoricoxib, Fenbufen, Fenoprofen, Flurbiprofen, Hydrocortisone, Ibuprofen, Indometacin, Indomethacin, Ketoprofen, Lumiracoxib, Mahidol University, Mefenamic, Meloxicam, Methylprednisolone, Nabumetone, Naproxen, Nimesulide, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Old Age Psychiatry: Sussex Partnership NHS Foundation Trust, Piroxicam, Prednisone, Ramathibodi Hospital, Sulindac, Sussex Partnership NHS Foundation Trust, Tenoxicam, Tiaprofenic Acid, Triamcinolone, University of Toronto | Leave a comment

Antipsychotics-Related Mortality Risk in Nursing Home Dementia Patients (BMJ / BBC News)

Posted on February 29, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 8, March 2012]. Summary Some antipsychotic medications increase the risk of death in patients with dementia more than others, according to a US study … Continue reading →

Posted in Acute Hospitals, Age UK, Antipsychotics, Community Care, Dementia Action Alliance, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Antipsychotics-Related Mortality Risks, Aripiprazole, Atypical Antipsychotics, BBC Health News, Behavioral and Psychological Symptoms of Dementia (BPSD), BMJ, BPSD: Behavioral and Psychological Symptoms of Dementia, Differemtial Antipsychotic-Related Mortality Risks, Differential Risk of Death (Antipsychotic Drugs), Haloperidol, Harvard Medical School, Medicaid, Medicare, Minimum Data Set, National Death Index, Nursing Homes, Nursing Homes in the United States, Olanzapine, Psychological Symptoms of Dementia (BPSD), Quetiapine, Risperidone, Ziprasidone | Leave a comment

Economic Evaluation of Alternatives to Antipsychotic Drugs for Individuals Living with Dementia (NHS Institute for Innovation and Improvement)

Posted on February 23, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 8, March 2012]. Summary This economic evaluation of the alternatives to antipsychotic drugs for people with dementia assembles the economic evidence about the benefits … Continue reading →

Posted in Acute Hospitals, Antipsychotics, Community Care, For Doctors (mostly), For Researchers (mostly), In the News, Management of Condition, National, NHS, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged Ann Curtis, Behavioral and Psychological Symptoms of Dementia (BPSD), Behavioural Alternatives to Antipsychotic Drugs, BPSD: Behavioral and Psychological Symptoms of Dementia, Cognitive Stimulation Therapy, Cognitive Stimulation Therapy (CST), Economic Evaluation, Joanne Knowles, Matrix Evidence, NHS Institute for Innovation and Improvement, Optima (University of Oxford’s Dementia Research Project), Psychological Symptoms of Dementia (BPSD), Psychosocial Interventions, Singing For The Brain, South Tees Hospitals Foundation Trust | Leave a comment

Evidence Update: Treatment of Depression in People With Dementia (NHS Evidence)

Posted on January 23, 2012 by Dementia Care News (an online adjunct to Dementia: the Latest Evidence)

Summary Depression is common in dementia. It often causes distress, reduces quality of life, worsens cognitive and functional impairment, increases mortality, and also brings about stress and depression in carers. Earlier Guidance The NICE Clinical Guideline on Dementia (CG42) recommends … Continue reading →

Posted in Acute Hospitals, Community Care, For Doctors (mostly), Guidelines, Management of Condition, National, NHS Evidence, Pharmacological Treatments, Proposed for Next Newsletter, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged Antidepressants, Antidepressants for Depression in Dementia (HTA-SADD), Depression, Depression / Dysphoria, Depression in Older People, Mirtazapine, National Institute for Health and Clinical Excellence (NICE), NICE, NICE Clinical Guideline CG90, NICE–SCIE Guideline on Supporting People with Dementia and Their Carers in Health and Social Care, Professor Sube Banerjee, Sertraline | Leave a comment

Category Archives: Pharmacological Treatments

Johnson & Johnson Fined $1.1bn Over Risperdal: Subversion of Science? (BBC Health News)

Cholinesterase Inhibitors for Dementia with Lewy Bodies, Parkinson’s Disease Dementia and Cognitive Impairment in Parkinson’s Disease (Cochrane Library)

Discontinuation of Antidepressants in People with Dementia and Neuropsychiatric Symptoms (DESEP Study) (BMJ)

Donepezil and Memantine for Moderate-to-Severe Alzheimer’s Disease (NEJM / BBC News)

Aspirin, Steroidal and Non-Steroidal Anti-Inflammatory Drugs for Alzheimer’s Disease?

Economic Evaluation of Alternatives to Antipsychotic Drugs for Individuals Living with Dementia (NHS Institute for Innovation and Improvement)

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