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Tag Archives: Beta-Amyloid
Blood Test Could Assist Early Diagnosis of Alzheimer’s Disease (BBC News)
Posted on March 11, 2013 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary Researchers at the University of Nottingham are developing a quick and easy blood test to detect proteins linked strongly with Alzheimer’s Disease, such as amyloid and APOE, in combination with other markers linked to inflammation. The test has not been fully validated yet, and could be … Continue reading →
Posted in Acute Hospitals, Alzheimer’s Research UK, BBC News, Community Care, Diagnosis, For Researchers (mostly), In the News, Proposed for Next Newsletter, Quick Insights, UK, Universal Interest
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Tagged Alzheimer's Gene (APOE4 Gene), Alzheimer’s Early Screening, Amyloid Beta, Amyloid Beta (Aβ42 and Aβ40), Amyloid Beta Protein, Amyloid-β (Aβ), APOE, ApoE and Genetics of Alzheimer's Disease, ApoE e4 Allele, APOE4 Gene, Apolipoprotein E (APOE) e4 Allele, BBC Health News, Beta-Amyloid, Beta-Amyloid Plaques, Biomarkers, Blood Tests, Case Finding for Patients with Dementia, Common Genetic Risk Factor Links Alzheimer’s Disease and Type 2 Diabetes (SorCS1), Dementia Case Finding, Diagnostic Markers, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Effective Diagnostics, Genetic Profiling, Genetics of Alzheimer's Disease, Inflammation, β-amyloid, Nottingham Trent University’s John van Geest Cancer Research Centre, Rapid Screening, Screening, Screening for Dementia, Targeted Screening for Dementia, University of Nottingham, University of Nottingham’s School of Molecular Medical Sciences
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Issues in the Clinical Diagnosis of Dementia with Lewy Bodies (Translational Neurodegeneration)
Posted on February 24, 2013 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary This article discusses recent progress, and problems remaining, in the clinical diagnosis of Dementia with Lewy Bodies (DLB). The sensitivity of accurate clinical diagnosis of DLB is said to be low. It seems likely that it may be possible … Continue reading →
Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Proposed for Next Newsletter, Universal Interest
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Tagged (123)I-FP-CIT: (123)I-2beta-carbometoxy-3beta-(4-iodophenyl)-N-(3-fluoropropyl) nortropane, Aβ Deposition in DLB, Amyloid Beta Protein, Antipsychotics: Neuroleptic Sensitivity, Assessment of Fluctuation Scales, Australia, Beta-Amyloid, Beta-Amyloid Plaques, CIND-PD: Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease (CIND-PD), DaTSCAN, Delusional Ideas, Delusions, Dementia in Parkinson's Disease, Dementia with Lewy Bodies, Dementia With Lewy Bodies (DLB), Dementia with Lewy Bodies Symptoms, Dementia with Lewy Bodies Translational Neurodegeneration, Diagnosis and Management of Dementias of Lewy Body Type in the NHS (DIAMAND-Lewy), Diagnosis and Screening: Dementia with Lewy Bodies, Differential Diagnosis, DLB: Dementia with Lewy Bodies, Dopamine, Dopamine Denervation, Early Differential Diagnosis, Fluctuating Cognition, Fluctuation Assessment Scales, Frederick Lewy, Genetics of DLB, Glucocerebrosidase Gene Mutations, Hallucinations, Hallucinations in People with Dementia, I-123 MIBG: Iodine-123 Metaiodobenzilguanidine, α-Synuclein, β-amyloid, β-amyloid Deposition, β-Amyloid Oligomerization, β-Synuclein, γ-Synuclein, Lewy Body Degeneration, Lewy Body Dementia, Lewy-Related Pathologies (LRP), Low Dopamine Transporter Uptake, LRP: Lewy-Related Pathology, Neuroleptic Sensitivity, Neuroscience Research Australia, Parkinson’s Disease Dementia, PDD: Parkinson's Disease with Dementia, Severe Neuroleptic Sensitivity, SPECT, Sydney, University of New South Wales, Visual Hallucinations
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Brain Scans Distinguish Between Dementia Types (BBC News / Neurology)
Posted on December 31, 2012 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary Scientists at the University of Pennsylvania believe they may have discovered how to distinguish between different types of dementia without the need for invasive lumbar puncture tests to obtain cerebrospinal fluid (csf). Alzheimer’s and frontotemporal dementia share similar features and symptoms and can … Continue reading →
Posted in BBC News, Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest
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Tagged Amyloid Beta, Amyloid Beta Protein, Assessment and Diagnosis, Beta-Amyloid, Cerebrospinal Fluid (CSF), Cerebrospinal Fluid (CSF) Biomarkers, CSF, CSF Aβ, CSF Tau, CSF tt/Aβ Ratios, Diagnosis and Assessment, Diagnosis and Screening: Frontotemporal Dementia, Diagnosis of Alzheimer's Disease, Diagnostic Errors, Diagnostic Markers, Early Differential Diagnosis, Frontotemporal Dementia, Frontotemporal Lobar Degeneration (FTLD), FTLD: Frontotemporal Lobar Degeneration, β-amyloid, Magnetic Resonance Imaging (MRI), MRI, MRI Scans, Tau, Tau Protein, Total Tau (T-tau), University of Pennsylvania
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Psoriasis Drug May Halt Alzheimer’s Disease?: “Behind the Headlines” Appraisal (NHS Choices / Nature Medicine)
Posted on November 28, 2012 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary The NHS Choices “Behind the Headlines” service produces regular critical appraisals of recent research about elderly care and dementia-related topics which have appeared in the news. Here is one more of these master-class evaluations. Animal Research on Psoriasis Drug … Continue reading →
Posted in Animal Studies, BBC News, For Doctors (mostly), For Researchers (mostly), In the News, International, Models of Dementia Care, NHS Choices, Pharmacological Treatments, Quick Insights, Universal Interest
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Tagged Alzheimer's Disease, Amyloid Beta, Amyloid Beta Protein, Antibodies Against p40, Behind the Headlines, Beta-Amyloid, Beta-Amyloid Plaques, Deutsche Forschungsgemeinschaft, IL-12, IL-23, β-amyloid, Koetzer Foundation, Mouse Model of Alzheimer's Disease, Nature Medicine, NeuroCure, p40, Psoriasis Drug for Alzheimer's Disease, Swiss National Science Foundation, University of Zurich, US National Institutes of Health, Ustekinumab
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Turmeric / Curcumin in Curry Helps Fight Dementia? (NHS Choices)
Posted on February 27, 2012 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary The Daily Mail and Daily Telegraph reported that eating a curry weekly could help to “stave off dementia”. Researchers tested the effects of curcumin (found in turmeric) on fruit flies (Drosophila melanogaster) genetically engineered to have a model of … Continue reading →
Posted in Animal Studies, In the News, NHS Choices, Proposed for Next Newsletter, Quick Insights, Universal Interest
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Tagged Aβ, Alice and Georg Olsson, Amyloid Beta, Amyloid Fibril Conversion, Amyloid-β (Aβ), ‘Hjärnfonden’ (the Brain Foundation), Beta-Amyloid, Curry, Drosophila melanogaster, European Union FP-7 Health Project LUPAS, Gustaf V Foundation, Jalfrezi, Knut and Alice Wallenberg Foundation, Korma, Linköping University in Sweden, Oligomeric Aβ, Swedish Foundation for Strategic Research, Swedish Research Council, Tau, Tau Protein, Transgenic Drosophila, Turmeric
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Alzheimer’s Brain Plaques Cleared Rapidly by Cancer Drug in Mice (BBC News / NHS Choices)
Posted on February 15, 2012 by Dementia and Elderly Care News (an online adjunct to Dementia and Elderly Care: the Latest Evidence)
Summary Clumps of a protein called beta-amyloid are a feature of Alzheimer’s Disease. The clearance of these plaques is widely thought to be a promising target for Alzheimer’s research. It has now been found that the destructive plaques found in the … Continue reading →
Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, NHS Choices, Proposed for Next Newsletter, Quick Insights, Universal Interest
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Tagged Aβ-Plaques, Animal Model, Animal Research, APOE, ApoE e4 Allele, Apolipoprotein E, Beta-Amyloid, Bexarotene (Targretin), Blanchette Hooker Rockefeller Fund, Case Western Reserve University, β-amyloid, Murine Model of Alzheimer's Disease, Peroxisome Proliferator Activated Receptor (PPARγ), Protein Plaques, Retinoid X Receptors (RXR), Roby and Taft Funds for Alzheimer’s, RXR Agonist, Skin Cancer Drug (Targretin), Thome Foundation
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