[This abstract first appeared in: Dementia: the Latest Evidence Newsletter RWHT Volume 1 Issue 3 October 2010].
Researchers from the University of Nottingham and Nottinghamshire County Teaching Primary Care Trust studied 25,532 eligible cases (15,975 with deep vein thrombosis and 9,557 with pulmonary embolism) recorded between 1996 and 2007 in people aged between 16 and 100.
An association was identified between being prescribed antipsychotic drugs and risk of venous thromboembolism in a large primary care population. The increased risk was more marked among new users and those prescribed atypical antipsychotic drugs.
This study provides further evidence that being prescribed the newer antipsychotic drugs increases the chances of developing dangerous blood clots.
This research tends to confirm evidence presented in a landmark 2009 document; “Report on the prescribing of anti-psychotic drugs to people with dementia: time for action”. Antipsychotic drugs increase the risk of deep vein thrombosis and pulmonary embolism, and have a serious detrimental effect of on the health of people with dementia.
Parker, C. Coupland, C. Hippisley-Cox, J. (2010). Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ. 2010 September 21st 2010, Vol.341(7774), c4245, pp.613, 641.