Ginkgo Biloba Extract for Alleviation of the Neuropsychiatric Symptoms of Dementia


This randomized, controlled, double-blind, multicenter clinical trial studied 410 outpatients with mild to moderate dementia to determine the effects of Ginkgo biloba extract EGb 761(®) on the neuropsychiatric symptoms of dementia.

Randomly allocated patients were given 240 mg of EGb 761(®) or a placebo once daily for a period of 24 weeks. Treatment with EGb 761(®) was significantly superior to the placebo for treatment of the symptoms apathy / indifference, sleep / night-time behavior, irritability / lability, depression / dysphoria, and aberrant motor behavior. Caregivers’ distress evaluation showed similar improvements.

Treatment with EGb 761(®), with a daily dose of 240 mg, was found to be safe, to effectively alleviate behavioral and neuropsychiatric symptoms in patients with mild to moderate dementia, and to improve the wellbeing of carers.

Full Text Link


Bachinskaya, N. Hoerr, R. [and] Ihl, R. (2011). Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial. Neuropsychiatric disease and treatment, April 20th 2011, Vol.7, pp.209-15. (Click here to view the PubMed abstract).

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Acute Hospitals, Community Care, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments, Universal Interest and tagged , , , , , , , , , , . Bookmark the permalink.

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