Ginkgo Biloba Extract for Alleviation of the Neuropsychiatric Symptoms of Dementia

Abstract

This randomized, controlled, double-blind, multicenter clinical trial studied 410 outpatients with mild to moderate dementia to determine the effects of Ginkgo biloba extract EGb 761(®) on the neuropsychiatric symptoms of dementia.

Randomly allocated patients were given 240 mg of EGb 761(®) or a placebo once daily for a period of 24 weeks. Treatment with EGb 761(®) was significantly superior to the placebo for treatment of the symptoms apathy / indifference, sleep / night-time behavior, irritability / lability, depression / dysphoria, and aberrant motor behavior. Caregivers’ distress evaluation showed similar improvements.

Treatment with EGb 761(®), with a daily dose of 240 mg, was found to be safe, to effectively alleviate behavioral and neuropsychiatric symptoms in patients with mild to moderate dementia, and to improve the wellbeing of carers.

Full Text Link

Reference

Bachinskaya, N. Hoerr, R. [and] Ihl, R. (2011). Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial. Neuropsychiatric disease and treatment, April 20th 2011, Vol.7, pp.209-15. (Click here to view the PubMed abstract).

Advertisements

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Acute Hospitals, Community Care, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments, Universal Interest and tagged , , , , , , , , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.