This study explores links between hypertension, vascular damage, and cognitive impairment, with attention being paid in particular to the decline in memory and executive functions as displayed by a cohort of hypertensive patients.
A progressive impairment of the executive function was found. The incidence of dementia was found to be double that of the general population. While initial memory impairment did not change during the evaluation period, cognitive impairment relating to executive function (prefrontal cortex) did get worse regardless of the adequacy of anti-hypertensive treatment and blood pressure values.
Vicario, A. Del Sueldo, MA. [and] Zilberman, JM. [et al] (2011). Cognitive evolution in hypertensive patients: a six-year follow-up. Vascular health and risk management. May 5th 2011, Issue 7, pp.281-5. (Click here to view the PubMed abstract).