PET in Dementia Diagnosis and Treatment (Applied Radiology)

[A brief reference to this item appears in: Dementia and Elderly Care: the Latest Evidence Newsletter (RWHT), Volume 3 Issue 3, October 2012].


The role of PET in the diagnosis and management of dementia is ex­pected to increase in future, both for preclinical / differential di­agnoses and for the evaluation of novel therapies cur­rently under development. Widespread availability of PET scanners makes this more practical and improved quantitative analysis methods has improved scan quality and diagnostic information.

Although single photon emission computed tomography (SPECT) has historically been the modality of choice for functional neuroimaging of de­mentia, this is being replaced by positron emission tomography (PET). SPECT assesses per­fusion mainly, whereas PET focuses on metabolism. Both PET and SPECT offer similar diagnostic information. The ad­vantages of PET over SPECT are better spatial resolution and ability to quantify changes. The most commonly used agent in PET imaging is F-18 fluorodeoxyglucose (FDG).

This article includes sections on the imaging and diagnosis of:

  • Alzheimer’s Disease (AD).
  • Diffuse Lewy Body Disease (DLB).
  • Parkinson’s Disease (PD).
  • Frontotemporal Lobar Dementia (FTD).

Full Text Link


Mehta, L. Thomas, S. (2012). The role of PET in dementia diagnosis and treatment. Applied Radiology, May 1st 2012, Vol.41(5), pp.8-15.

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Parkinson's Disease, Quick Insights, Universal Interest and tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.