The authors of this systematic review attempted to evaluate the efficacy of cognitive interventions for patients with Alzheimer’s Disease (AD), estimate their feasibility and assess their cost-effectiveness. On the basis of four randomised controlled trials of cognitive intervention it was found that global cognitive functioning showed significant intervention effects (as measured by Mini-Mental State Examination) but no clear effects were discernible otherwise. The authors highlight a shortage of well-controlled trials in this area and advise caution in interpreting results in advance of higher-quality research in future.
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Alves, J. Magalhães, R. [and] Thomas, RE. [et al] (2013). Is there evidence for cognitive intervention in alzheimer disease? A systematic review of efficacy, feasibility, and cost-effectiveness. Alzheimer Disease and Associated Disorders, January 2013, Epub ahead of print. (Click here to view the PubMed abstract).