Antipsychotics for Delirium in General Hospitals (International Journal of Geriatric Psychiatry)


This article discusses a prospective observational study, conducted over 1 year at 33 general hospitals in Japan, into the risks and benefits of antipsychotics for older patients with delirium in general hospital settings.

Of 2834 patients who developed delirium, 2453 patients received antipsychotics such as risperidone, quetiapine, and parenteral haloperidol as a treatment for delirium. Just 22 patients developed serious adverse events, the most common being aspiration pneumonia (17 patients, 0.7%), followed by cardiovascular events (4 patients, 0.2%) and venous thromboembolism (1 patient, 0.0%). Injuries due to falls did not appear to be an outcome, and no one died from antipsychotic side effects.

The authors conclude that the risk of antipsychotics for older patients with delirium can be low in general hospital settings and with careful management (compared with well-documented adverse outcomes of antipsychotics for dementia in the nursing homes and outpatient settings). Risk monitoring may be important.

Full Text Link


Hatta, K. Kishi, Y. [and] Wada, K. [et al] (2013). Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study. International Journal of Geriatric Psychiatry, June 25th 2013, [Epub ahead of print]. (Click here to view the PubMed abstract).

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Acute Hospitals, Antipsychotics, Delirium, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Pharmacological Treatments, Quick Insights and tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.