A trial is underway at Imperial College London, King’s College and sites in Oxford, Southampton and Swindon, to determine whether the drug Liraglutide used to treat diabetes might slow the progression of Alzheimer’s Disease.
The study will involve 200 patients with memory problems indicative of early Alzheimer’s Disease. Earlier laboratory research suggests that Liraglutide reduces brain inflammation, and improves the growth of brain cells and the connections between cells. Liraglutide is a tried and tested diabetes treatment, known to be safe.
Participants in the trial will receive an injection of Liraglutide, or a placebo, daily for 12 months. They will be given brain scans and memory tests before and after the treatment. The trial is expected yield evidence within three years on whether Liraglutide can help to slow the progression of Alzheimer’s Disease.
Read more: BBC News. Could diabetes drug slow Alzheimers?.
Walsh, F. (2013). Could diabetes drug slow Alzheimer’s? London: BBC Health News, December 10th 2013.
Diabetes drug may reverse Alzheimer’s and enters major clinical trial. London: Alzheimer’s Society, September 11th 2013.