The detection of pre-clinical Alzheimer’s Disease appears to be accomplished best by the use of a combination of information, taken from targeted neuroimaging and complementary neuropsychological assessments of cognitive functioning. This combination of approaches may be necessary in order to capture both the structural and functional changes associated with disease progression.
Test could give two-year warning for Alzheimer’s. London: NHS Choices Behind the Headlines, December 9th 2013.
This relates to:
Peters, F. Villeneuve, S. [and] Belleville, S. (2013). Predicting progression to dementia in elderly subjects with mild cognitive impairment using both cognitive and neuroimaging predictors. Journal of Alzheimer’s Disease: JAD, 2013, Vol.38(2), pp.307-18. (Click here to view the PubMed abstract).