Monthly Archives: January 2014

Integrated Care for Older People with Complex Needs: International Case Studies (King’s Fund)

Posted on January 31, 2014 by Dementia and Elderly Care News

Summary This King’s Fund report compares evidence from case studies from Australia, Canada, the Netherlands, New Zealand, Sweden, UK and United States to discover generalisable conclusions. Models vary. The underlying similarities and international differences between various programmes for delivering integrated … Continue reading →

DDT (Pesticide): Potential Link with Alzheimer’s Disease (BBC News / JAMA Neurology)

Posted on January 30, 2014 by Dementia and Elderly Care News

Summary Exposure to the pesticide DDT, which was used commonly after WW2, may increase the risk of developing Alzheimer’s Disease, according to research published in JAMA Neurology. Patients with Alzheimer’s Disease, statistically, had four times more residual DDT lingering in … Continue reading →

Posted in BBC News, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Choices, Quick Insights, Statistics, Universal Interest | Tagged Amyloid Precursor Protein (APP), Apolipoprotein E, Apolipoprotein E (APOE) e4 Allele, Apolipoprotein E (APOE) Gene, BBC Health News, Behind the Headlines, Critical Appraisals, DDE, DDT (Pesticide), Department of Environmental and Occupational Medicine: Rutgers Robert Wood Johnson Medical School, Department of Neurology and Alzheimer's Disease: Emory University School of Medicine, Department of Pathology: Emory University School of Medicine, Department of Psychiatry: University of Texas Southwestern Medical Center, Dichlorodiphenyldichloroethylene (DDE), Dichlorodiphenyltrichloroethane (DDT), Elevated Serum Pesticide Levels, Emory University, Environmental and Lifestyle Factors, Environmental and Occupational Health Sciences Institute: Rutgers University, Epidemiology, Epidemiology and Statistics, JAMA Neurology, Pesticides, Pesticides and Dementia, Risk Factors, Risk Factors for Alzheimer's Diseease, Rutgers University, Serum Pesticide Levels | Leave a comment

CQC Monitoring of the Mental Health Act (BBC News / CQC)

Posted on January 30, 2014 by Dementia and Elderly Care News

Summary The number of people in England detained under the Mental Health Act has risen by 12% during the past five years, according to the Care Quality Commission (CQC). The Mental Health Act was used over 50,000 times to detain patients … Continue reading →

Local Interventions to Reduce Health Inequalities (British Academy for the Humanities and Social Sciences)

Posted on January 29, 2014 by Dementia and Elderly Care News

Summary This document is a collection of opinions from leading social scientists on how to reduce health inequalities. Each article presents the evidence base for a particular area, and identifies the policy interventions which local authorities could introduce to improve … Continue reading →

Eldest Age Group’s Ambulance Trips to Accident and Emergency Rising Disproportionately (BBC News)

Posted on January 29, 2014 by Dementia and Elderly Care News

Summary The number of over-90s taken to A&E by ambulance in England has risen by 81% over the past three years, rising from approximately 165,910 in 2009-10 to 300,370 during 2012-13. Overall 999 trips to A&Es, for all age-groups, rose by 11% … Continue reading →

Posted in Acute Hospitals, BBC News, Commissioning, Community Care, For Carers (mostly), For Nurses and Therapists (mostly), For Social Workers (mostly), In the News, Integrated Care, National, NHS, Quick Insights, Standards, Statistics, UK, Universal Interest | Tagged Accident and Emergency Departments, Accident and Emergency Statistics, Age and Ageing, Ageing, Ageing and Society, Ageing Population, Avoidable Admissions, Avoidable Rehospitalisations, BBC Health News, Care Integration, Care of Frail Older People With Complex Needs, Coordinated Care, Emergency Admission Rates in UK, Emergency Admissions, Emergency Ambulance Services, Emergency and Urgent Care Services, Emergency Care, Emergency Departments, Frail Elders, Frail Older People With Complex Needs, Health and Social Care Information Centre (HSCIC), Hospital Episode Statistics: Accident and Emergency Statistics, Hospital Episodes Statistics (HES), HSCIC: Health and Social Care Information Centre, Inappropriate Accident and Emergency Department Attendances, Labour Party, Oldest Old, Oldest Old in the United Kingdom, Preventable Hospital Admissions, Primary Care, Primary Care Alternatives to Emergency Hospital Admissions, Primary Care Service Interventions, Reducing Inappropriate Accident and Emergency Department Attendances, Reducing Unnecessary Admissions, Reducing Unscheduled Admissions, Unnecessary Hospital Admissions, Unplanned Hospital Admissions, Unscheduled Admissions, Urgent and Emergency Care, Urgent and Emergency Services, Wellbeing and an Ageing Population | Leave a comment

Bapineuzumab Trials Results in Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)

Posted on January 28, 2014 by Dementia and Elderly Care News

Summary Bapineuzumab is an anti-amyloid-beta monoclonal antibody, which had shown promise for the treatment of Alzheimer’s Disease. Two double-blind, randomised, placebo-controlled, phase 3 trials have been conducted, involving 2204 patients with mild-to-moderate Alzheimer’s disease. One trial involved 1121 carriers of … Continue reading →

Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments | Tagged Alzheimer's Disease Assessment Scale (ADAS-Cog11), Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Apolipoprotein E, Apolipoprotein E (APOE) e4 Allele, Apolipoprotein E (APOE) Gene, Bapineuzumab 301, Bapineuzumab 302, Bapineuzumab for Mild-to-Moderate Alzheimer's Disease, Bapineuzumab Trials, Beta-Amyloid, Beta-Amyloid Plaques, Brigham and Women's Hospital: Boston, Butler Hospital, Cerebrospinal Fluid Phosphorylated Tau (Phospho-Tau) Concentrations, Cleo Roberts Center for Clinical Research, Clinical Trials Number NCT00574132, Clinical Trials Number NCT00575055, Columbia University, Disability Assessment for Dementia-DAD, EudraCT Number 2009-012748-17, Institute of Neurology: University College London, Janssen Alzheimer Immunotherapy and Pfizer, Janssen Alzheimer Immunotherapy Research and Development, New England Journal of Medicine, New York University Langone Medical Center, Pfizer, Pittsburgh Compound B (PIB-PET), Sahlgrenska University Hospital, Sun Health Research Institute, Sweden, University College London, University of California, University of Göteborg, University of Pittsburgh, University of Rochester School of Medicine and Dentistry, Veterans Affairs Medical Center | Leave a comment

Solanezumab Trials Results for Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)

Posted on January 28, 2014 by Dementia and Elderly Care News

Summary Solanezumab is a monoclonal antibody which binds soluble amyloid preferentially and had shown some promise of promoting better clearance of amyloid-beta from the brain in pre-clinical studies. Two placebo controlled trials (EXPEDITION 1 and EXPEDITION 2) of 1012 and … Continue reading →

Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments | Tagged Alzheimer's Disease and Memory Disorders Center: Baylor College of Medicine (Houston), Alzheimer's Disease Assessment Scale (ADAS-Cog11), Alzheimer's Disease Cooperative Study Steering Committee, Alzheimer's Disease Cooperative Study-Activities of Daily Living scale (ADCS-ADL), Alzheimer's Disease Cooperative Study: University of California at San Diego, Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Baylor College of Medicine, Beta-Amyloid, Beta-Amyloid Plaques, Center for Human Experimental Therapeutics: University of Rochester Medical Center, Centre Hospitalier Universitaire Toulouse, Clinical Trials Number: NCT00904683, Clinical Trials Number: NCT00905372, Department of Neuropathology: University of Tokyo, Eli Lilly, Gerontopole: Unité Mixte de Recherche, Gliosis, Indiana Alzheimer Disease Center: Indiana University, Indiana University, β-amyloid, Neurofibrillary Tangles, Neuronal Loss, New England Journal of Medicine, Solanezumab for Mild-to-Moderate Alzheimer’s Disease, Solanezumab Study Group, Solanezumab Trials, Solanezumab: Humanised Monoclonal Antibody, University of California at San Diego, University of Pennsylvania, University of Rochester Medical Center | Leave a comment

Monthly Archives: January 2014

DDT (Pesticide): Potential Link with Alzheimer’s Disease (BBC News / JAMA Neurology)

Bapineuzumab Trials Results in Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)

Solanezumab Trials Results for Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)

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