Recent Systematic Reviews and Meta-Analyses on Pharmacological Treatments

Some of the following articles may be available freely where indicated (depending on local circumstances). Access to the full-text of the other articles will require a suitable Athens password, a journal subscription or payment.

The Bibliographic Citations

Irwin, RW. Brinton, RD. (2014). Allopregnanolone as regenerative therapeutic for Alzheimer’s Disease: translational development and clinical promise. Progress in Neurobiology. February 2014; 113: 40-55.

Schneider, LS. Mangialasche, F. Andreasen, N. [et al] (2014). Clinical trials and late-stage drug development for Alzheimer’s disease: an appraisal from 1984 to 2014. Journal of Internal Medicine. March 2014; 275(3): 251-83. Full Text Link.

Brondino, N. Re, S. Boldrini, A. [et al] (2014). Curcumin as a therapeutic agent in dementia: a mini systematic review of human studies. ScientificWorldJournal. January 22nd 2014; 174282. Review. Full Text Link.

van der Cammen, TJ. Rajkumar, C. Onder, G. [et al] (2014). Drug cessation in complex older adults: time for action. Age and Ageing. January 2014; 43(1): 20-5.

van den Elsen, GA. Ahmed, AI. Lammers, M. [et al] (2014). Efficacy and safety of medical cannabinoids in older subjects: a systematic review. Ageing Research Reviews. February 5th 2014. [Epub ahead of print].

Tampi, RR. Tampi, DJ. (2014). Efficacy and tolerability of benzodiazepines for the treatment of behavioral and psychological symptoms of dementia: a systematic review of randomized controlled trials. American Journal of Alzheimer’s Disease and Other Dementias. March 6th 2014. [Epub ahead of print].

Cano-Cuenca, N. Solís-García del Pozo, JE. Jordán, J. (2014). Evidence for the efficacy of latrepirdine (Dimebon) treatment for improvement of cognitive function: a meta-analysis. Journal of Alzheimer’s Disease: JAD. 2014; 38(1): 155-64.

Salahudeen, MS. Duffull, SB. Nishtala, PS. (2014). Impact of anticholinergic discontinuation on cognitive outcomes in older people: a systematic review. Drugs  & Aging. March 2014; 31(3): 185-92.

Holliday, SF. Kane-Gill, SL. Empey, PE. [et al] (2014). Interpatient variability in dexmedetomidine response: a survey of the literature. ScientificWorldJournal. 2014; 805013. Review. Full Text Link.

Kongkeaw, C. Dilokthornsakul, P. Thanarangsarit, P. [et al] (2014). Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. Journal of Ethnopharmacology. January 10th 2014; 151(1): 528-35. Full Text Link.

Sampson, EL. Jenagaratnam, L. McShane, R. (2014). Metal protein attenuating compounds for the treatment of Alzheimer’s dementia. Cochrane Database Systematic Reviews. February 21st 2014; Issue 2: No. CD005380. Full Text Link.

Gosch, M. Nicholas, JA. (2014). Pharmacologic prevention of postoperative delirium. Zeitschrift fur Gerontologie und Geriatrie. February 2014; 47(2): 105-109.

Friedman JI, Soleimani L, McGonigle DP, Egol C, Silverstein JH. Pharmacological treatments of non-substance-withdrawal delirium: a systematic review of prospective trials. American Journal of Psychiatry. February 1st 2014; 171(2): 151-9.

Mikulca, JA. Nguyen, V. Gajdosik, DA. [et al] (2014). Potential novel targets for Alzheimer pharmacotherapy: II. Update on secretase inhibitors and related approaches. Journal of Clinical Pharmacy and Therapeutics. February 2014; 39(1): 25-37. Full Text Link.

Hirota, T. Kishi, T. (2013). Prophylactic antipsychotic use for postoperative delirium: a systematic review and meta-analysis. Journal of Clinical Psychiatry. December 2013; 74(12): e1136-44.

Atti, AR. Ferrari Gozzi, B. Zuliani, G. [et al] (2014). A systematic review of metabolic side effects related to the use of antipsychotic drugs in dementia. International Psychogeriatrics. January 2014; 26(1): 19-37.

Su, Y. Wang, Q. Wang, C. [et al] (2014). The treatment of Alzheimer’s disease using Chinese Medicinal Plants: from disease models to potential clinical applications. Journal of Ethnopharmacology. January 9th 2014. [Epub ahead of print]. Review.

Welsh, TJ. Gladman, JR. Gordon, AL. (2014). The treatment of hypertension in people with dementia: a systematic review of observational studies. BMC Geriatrics. February 12th 2014; 14: 19. Full Text Link.

[A version of this collection features in Dementia and Elderly Care: the Latest Evidence Newsletter (RWNHST), Volume 3 Issue 11, June 2014].

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
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