Summary
French research into the impact of a premature menopause (≤40 years) on cognitive function in later life indicates that premature surgical menopause and premature ovarian failure are associated with long-term negative effects on cognitive function. These effects are not offset by menopausal hormone therapy (HT) completely. The potential long-term effects on cognitive function should be included in the risk / benefit considerations for surgical menopause (ovariectomy) in younger women.
No significant link was discovered between premature menopause and the risk of dementia in later life.
Reference
Early menopause linked to mental decline. London: NHS Choices Behind the Headlines, May 8th 2014.
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Reference
Ryan, J. Scali, J. [and] Carrière, I. [et al] (2014). Impact of a premature menopause on cognitive function in later life. BJOG: International Journal of Obstetrics and Gynaecology. May 7th 2014. [Epub ahead of print]. (Click here to view the PubMed abstract).