More on the Association Between Dementia and Poor Sleep Quality (NHS Choices / Nature Neuroscience)

Summary

Recent US research found an apparent link between poor sleep quality and higher levels abnormal protein (beta-amyloid plaques) in the brain. The following NHS Choices Behind the Headlines critical appraisal puts the limitations of this interesting research into perspective.

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Reference

Poor sleep quality linked to Alzheimer’s Disease. London: NHS Choices Behind the Headlines, June 3^rd 2015.

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Reference

Mander, BA. Marks, SM. [and] Vogel, JW. [et al] (2015). β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nature Neuroscience. July 2015, Vol.18(7), pp.1051-7. (Click here to view the PubMed abstract).