Animal research at the University of Southampton, funded by the Medical Research Council (MRC) and Alzheimer’s Research UK indicates that blocking a receptor (CSF1R), which is responsible for regulating the production of new immune cells (microglia) in the brain, might help protect against progression of Alzheimer’s Disease in mice.
Blocking brain inflammation ‘halts Alzheimer’s disease’. London: BBC Health News, January 8th 2016.
Study shows beneficial effects of blocking brain inflammation in an experimental model of Alzheimer’s. London: Medical Research Council (MRC), January 8th 2016.
Targeting inflammation ‘could help treat Alzheimer’s disease’. London: NHS Choices Behind the Headlines, January 8th 2015.
This relates to:
Olmos-Alonso, A. Schetters, ST. [and] Sri, S. [et al] (2016). Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology. Brain: a Journal of Neurology. January 8th 2016. [Epub ahead of print]. (Click here to view the PubMed abstract).