A number of drugs, already approved as safe for the treatment of other conditions, and which could help protect against Alzheimer’s Disease, are said to have been detected and short-listed for further investigation.
Alzheimer’s preventative drug hope. London: BBC Health News, February 13th 2016.
Possibly of interest, about an approved anticancer drug thought to target selectively the first step in the molecular cascade resulting in Alzheimer’s Disease:
Habchi, J. Arosio, P. [and] Perni, M. [et al] (2016). An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease. Science Advances. February 12th 2016, 2016; 2 : e1501244.
A pinch of context (critical appraisal):
Alzheimer’s disease ‘wonder drug’ claims are premature. London: NHS Choices Behind the Headlines, February 15th 2016.
A recent USA trial involving humans:
Cummings, JL. Zhong, K. [and] Kinney, JW. [et al] (2016). Double-blind, placebo-controlled, proof-of-concept trial of bexarotene X in moderate Alzheimer’s disease. Alzheimer’s Research and Therapy. January 29th 2016, Vol.8(1), 4. (Click here to view the PubMed abstract).