Research at the University of Edinburgh indicates that test for synuclein, which measures how sticky this protein molecule has become (i.e. alpha-synuclein aggregation), might be the key to diagnosing accurately the early stages of both Parkinson’s Disease and Dementia with Lewy Bodies (DLB).
The technique – called a real-time quaking-induced conversion (RT-QuIC) based assay – has been used previously to test for Creutzfeldt-Jakob Disease (CJD); but this test is unsuitable for the early detection of other types of dementia including Alzheimer’s Disease.
Parkinson’s protein test could lead to earlier diagnosis. London: BBC Health News, August 29th 2016.
This relates to:
Fairfoul, G. McGuire, LI. [and] Pal, S. (2016). Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies. Annals of Clinical and Translational Neurology. August 28th 2016.