Animal research in the United States and Sweden suggests that Parkinson’s Disease may be caused by bacteria living in the gut. It appears likely that the certain gut bacteria (the “gut microbiome”) could be responsible for releasing chemicals (SCFAs) which may trigger immune cells in the brain to cause the neurodegenerative damage behind Parkinson’s pathogenesis.
Gallagher, J. (2016). Parkinson’s disease ‘may start in gut’. London: BBC Health News, December 2nd 2016.
This relates to:
Sampson, TR. Debelius, JW. [and] Thron, T. [et al] (2016). Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s Disease. Cell. December 1st 2016; 167(6): 1469-1480.e12.
See further commentary:
Could Parkinson’s disease start in the gut? London: NHS Choices; Behind the Headlines, December 2nd 2016.