Persons aged over 75 taking daily aspirin following a stroke or heart attack are at higher risk of stomach bleeds than thought previously. The benefits of low dose aspirin still outweigh the risks, even in this age group. Co-prescription of stomach-protecting proton-pump inhibitors (PPIs) is now recommended as a means of reducing upper gastrointestinal bleeds, possibly by 70–90%.
Mundasad, S. (2017). Aspirin ‘major bleed’ warning for over-75s. London: BBC Health News, June 14th 2017.
This relates to:
Li, L. Geraghty, OC. [and] Mehta, Z. [et al] (2017). Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. Lancet. June 13th 2017. [Epub ahead of print].
Risk of aspirin-related bleeding is higher in the over-75s. London: NHS Choices; Behind the Headlines, June 14th 2017.