Early animal research indicates that a new drug designed for the future treatment of diabetes may (one day) have an alternative re-use for reducing the memory-loss symptoms of Alzheimer’s Disease. Mice given a modified version of a so-called triple receptor agonist (TA) drug appear to show reduced / reversed memory loss (as measured by better performance in water mazes) in transgenic mice.
The following NHS Choices Behind the Headlines critical appraisal offers a sense of perspective and cautions against jumping to premature conclusions based on this interesting research.
Diabetes drug may help with memory loss in dementia. London: NHS Choices; Behind the Headlines, January 2nd 2018.
This relates to:
Tai, J. Liu, W. [and] Li, Y. [et al] (2018). Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer’s disease. Brain Research. January 1st 2018; 1678: pp.64-74.