Animal Study Explores the Potential of a Novel Diabetes Drug for Reducing Memory Loss in Dementia – In Mice (NHS Choices / Brain Research)


Early animal research indicates that a new drug designed for the future treatment of diabetes may (one day) have an alternative re-use for reducing the memory-loss symptoms of Alzheimer’s Disease. Mice given a modified version of a so-called triple receptor agonist (TA) drug appear to show reduced / reversed memory loss (as measured by better performance in water mazes) in transgenic mice.

The following NHS Choices Behind the Headlines critical appraisal offers a sense of perspective and cautions against jumping to premature conclusions based on this interesting research.

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Diabetes drug may help with memory loss in dementia. London: NHS Choices; Behind the Headlines, January 2nd 2018.

This relates to:

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Tai, J. Liu, W. [and] Li, Y. [et al] (2018). Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer’s disease. Brain Research. January 1st 2018; 1678: pp.64-74.

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Alzheimer's Society, Animal Studies, Charitable Bodies, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest and tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Bookmark the permalink.

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