A Journal of Geriatric Care and Research (JGCR) case report discusses the neuropsychological assessments preparatory to the differential diagnosis of Primary Progressive Aphasia (PPA). PPA is a rare form of non-Alzheimer’s dementia featuring language impairment with progressive decline in word finding and comprehension.
“Appropriate use of suggested criteria and neuropsychological assessments may prevent the risk of misdiagnosis and may help the patient in receiving appropriate supportive measures early”. (p.7).
Nwaubani, P. [and] Nazir, E. Primary progressive aphasia: a case report on diagnostic issues. Journal of Geriatric Care and Research (JGCR). March / April 2018, 5(1): 6-8.
The diagnosis and management of the three main variants of PPA, namely non-fluent / agrammatic variant (nfvPPA), semantic variant (svPPA) and logopenic variant (lvPPA), are explored further in the following article:
Marshall, CR. Hardy, CJD. [and] Volkmer, A. [et al] (2018). Primary progressive aphasia: a clinical approach. Journal of Neurology. February 1st 2018. [Epub ahead of print].
Patient information on this subject is available from Alzheimer’s Research UK:
What is primary progressive aphasia (PPA)? London: Alzheimer’s Research UK, 2017.
Mis-Diagnosis Arising From Language Differences?
As a result of international differences between the structure of different languages (English versus Italian, for example) it is possible that patients with PPA may receive an incorrect (false negative) diagnosis when their symptoms don’t match those described in clinical texts based on studies of English speakers.
Languages affected differently by brain disease. London: BBC Health News, January 11th 2020.