A recent systematic review of studies into the role of Vitamin D exposure levels / deficiency or supplementation in four neurodegenerative diseases (Alzheimer’s Disease, Motor Neurone Disease, Multiple Sclerosis (MS) and Parkinson’s Disease) found little conclusive evidence for any supposed neuroprotective benefits from Vitamin D.
Oddly, sunlight / ultra-violet (UV) exposure, independent of Vitamin D production, may be protective against multiple sclerosis. Vitamin D supplementation appears not to be an effective substitute for UV exposure in providing any protection against neurodegenerative diseases.
More research is required.
“We know that Vitamin D keeps bones, teeth and muscles healthy. But based on the available research, we can’t say whether Vitamin D is good for the brain”.
‘No solid evidence’ vitamin D keeps the brain healthy. London: NHS Choices; Behind the Headlines, July 12th 2018.
This relates to:
Full Text Link (Note: This article requires a suitable Athens password, a journal subscription or payment for access).
Iacopetta, K. Collins-Praino, LE. [and] Buisman-Pijlman, FTA. [et al] (2018). Are the protective benefits of Vitamin D in neurodegenerative disease dependent on route of administration? A systematic review. Nutritional Neuroscience. July 9th 2018: 1-30. [Epub ahead of print].
Likely interest, but equally inconclusive:
Aghajafari, F. Pond, D. [and] Catzikiris, N. [et al] (2018). Quality assessment of systematic reviews of Vitamin D, cognition and dementia. BJPsych Open. July 2018; 4(4): 238-249.