Further evidence implying that the gut may be involved in the development of Parkinson’s Disease has emerged. Toxic (alpha-synuclein) proteins associated with Parkinson’s Disease tend to accumulate in the appendix, and it seems that people who have had their appendix removed face a 20% lower risk of Parkinson’s in later life. It is speculated that the rogue proteins may travel up via the vagus nerve into the brain.
Gallagher, J. (2018). Parkinson’s disease ‘may’ start in gut. London: BBC Health News, October 31st 2018.
This relates to:
Killinger, BA. Madaj, Z. [and] Sikora, JW. [et al] (2018). The vermiform appendix impacts the risk of developing Parkinson’s disease. Science Translational Medicine. October 31st 2018.