Research from Finland discovered a 9% to 17% increase in the risk of developing Alzheimer’s Disease in women taking hormone replacement therapy (HRT) for more than 10 years.
The public has been advised not to be overly concerned, as absolute risk elevations are small:
“This equates to between nine and 18 extra cases of the disease per year in every 10,000 women aged between 70 and 80”.
HRT: Women told not to be alarmed by Alzheimer’s study. London: BBC Health News, March 7th 2019.
This relates to:
Savolainen-Peltonen, H. Rahkola-Soisalo, P. [and] Hoti, F. [et al] (2019). Use of postmenopausal hormone therapy and risk of Alzheimer’s disease in Finland: nationwide case-control study. British Medical Journal (BMJ). March 6th 2019. [Epub ahead of print].
‘Small’ increase in risk of Alzheimer’s disease with HRT use, study suggests. London: NHS Digital (previously NHS Choices); Behind the Headlines, March 7th 2019.