Results from the Hygia Chronotherapy Trial suggest that blood pressure medicines may be more effective at lowering blood pressure, and reducing the risk of heart attacks and / or stroke, when taken at bedtime.
Roberts, M. (2019). Blood pressure pills ‘work better at bedtime’. London: BBC Health News, October 23rd 2019.
This relates to:
Hermida, RC. Crespo, JJ. Domínguez-Sardiña, M. [et al]; Hygia Project Investigators (2019). Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial. European Heart Journal. October 22nd 2019. [Epub ahead of print].
There is a critical appraisal / commentary on this research:
Could blood pressure tablets be more effective if taken at bedtime? London: NHS Digital Behind the Headlines, October 24th 2019.