Updates Relating to the Lancet Commission on Dementia Prevention, Intervention, and Care (Lancet / Alzheimer’s Research and Therapy / Alzheimer’s and Dementia)

Summary

The Lancet Commission on Dementia Prevention, Intervention, and Care has updated evidence on modifiable risk factors the prevention of dementia, and the “life-course model of dementia prevention”. There were nine modifiable risk factors for reducing the risk of dementia originally; this model has subsequently been extended with an updated 12 risk factor life-course model of dementia prevention.

The potential for dementia prevention may be higher in low-income and middle-income countries (LMIC) where dementia is more prevalent.

Information on multimorbidity, hospital admissions, pharmacological, non- pharmacological, psychological, and social interventions has been updated, with a new section on dementia and COVID-19.

Full Text Link

Reference

Livingston, G. Huntley, J. [and] Sommerlad, A. [et al]. (2020). Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. July 29th 2020; [Epub ahead of print].

“ …up to 35% of dementia cases could be prevented by modifying nine risk factors [around 40% for the 12 risk factors]: low education, midlife hearing loss, obesity, hypertension, late-life depression, smoking, physical inactivity, diabetes, and social isolation”.

Some commentators suggest the strength of the evidence in favour of interventions to promote this good advice may be more modest than expected.

Full Text Link

Reference

Montero-Odasso, M. Ismail, Z. [and] Livingston, G. (2020). One third of dementia cases can be prevented within the next 25 years by tackling risk factors. The case “for” and “against”. Alzheimer’s Research and Therapy. July 8th 2020, Vol.12(1), 81.

Possibly also of interest:

Full Text Link (Note: This article requires a suitable Athens password, a journal subscription or payment for access).

Reference

Kivipelto, M. Mangialasche, F. [and] Snyder, HM. [et al]. (2020). World-Wide FINGERS Network: a global approach to risk reduction and prevention of dementia. Alzheimer’s and Dementia: the journal of the Alzheimer’s Association. July 2020; Vol.16(7): pp.1078-1094.

Regarding Risk Factors Reduction for Alzheimer’s Disease

“Distribution of modifiable factors with Class I recommendation throughout the course of life… Class I suggestions: risk factors include 10 factors with Level A evidence (cognitive activity, hyperhomocysteinaemia, increased BMI in late life, depression, stress, diabetes, head trauma, hypertension in midlife, orthostatic hypotension and education) and 9 factors (obesity in midlife, weight loss in late life, physical exercise, smoking, sleep, CVD, frailty, atrial fibrillation and vitamin C) with Level B evidence”.

Full Text Link

Reference

Yu, JT. Xu, W. [and] Tan, CC. [et al]. (2020). Evidence-based prevention of Alzheimer’s disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. Journal of Neurology, Neurosurgery, and Psychiatry. July 20th 2020 [Epub ahead of print].

Possibly also of interest, a literature review prepared for, and presented at, the “Healthy Ageing 2020” International Conference, organised by GeriCaRe (Geriatric Care and Research Organisation) on August 8th 2020.

Full Text Link

Reference

Jolley, D. (2020). Approaches to reduce the incidence of cognitive decline and dementia. Journal of Geriatric Care and Research (JGCR). August 22nd 2020. [Epub ahead of print].

Prevention of Cardiovascular Disease (CVD): the CVDPREVENT National Primary Care Audit

The idea behind CVDPREVENT is to extract data from primary care, to better understand how many patients with the high-risk conditions – hypertension (high blood pressure), high cholesterol and atrial fibrillation (AF) – are undiagnosed, under-treated or over-treated.

The CVDPREVENT Implementation Steering Group comprises representatives from RCGP, NHS Digital, NICE, Public Health England, NHS England and NHS Improvement, British Heart Foundation, Royal Pharmaceutical Society, Primary Care Cardiovascular Society and GPs.

Full Text Link

Reference

CVDPREVENT. London: NHS England, August 2020.

About Dementia and Elderly Care News

Dementia and Elderly Care News. Wolverhampton Medical Institute: WMI. (jh)
This entry was posted in Commissioning, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, International, Management of Condition, Mental Health, Models of Dementia Care, National, Non-Pharmacological Treatments, Nutrition, Person-Centred Care, Pharmacological Treatments, Quick Insights, Statistics, Systematic Reviews, UK, Universal Interest and tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.