Category Archives: International

Research involving non-UK agencies and/or international bodies. Includes both foreign and UK non-English e.g. Scottish, Welsh etc.

Pseudomedicine and Potential Dementia Treatments? (JAMA)

Posted on February 15, 2019 by Dementia and Elderly Care News

Summary A United States perspective covers the growing market for complementary interventions to promote brain health or minimise dementia risk and/or symptoms. Health professionals are requested to help the public understand commercial conflicts of interest and the market forces behind … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Ageing Population, Brain Health Supplements, Cargo Cult Science (Feynman), Complementary and Alternative Medicine, Complementary and Alternative Therapies, Complementary Therapies, Conflicts of Interest, Dietary Supplements, Drug Efficacy, Drug Side-Effects, Drugs Alleged to Raise False Hopes (Speculative Construct), Evidence Uncertainties, JAMA, Journal of the American Medical Association (JAMA), Later Life, Neurological Disorders, Pseudomedicine, Pseudomedicine for Brain Health, Pseudomedicine for Dementia, Pseudoscience, Tolerance of Ambiguity, USA | Leave a comment

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Posted on January 28, 2019 by Dementia and Elderly Care News

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged APP or PSEN Mutations, Australia, Basel, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Columbia University Medical Center, Dementia Research Centre, Dementia Research Centre: University College London, Department of Biomedical Sciences: Macquarie University, Department of Cellular Neurology: Hertie Institute for Clinical Brain Research, Department of Neurodegeneration: Queen Square Institute of Neurology, Department of Neurology: Columbia University Medical Center, Department of Neurology: Keck School of Medicine at USC, Department of Neurology: Ludwig-Maximilians-Universität München, Department of Neurology: Massachusetts General Hospital, Department of Neurology: Mayo Clinic Jacksonville, Department of Neurology: Washington University School of Medicine, Department of Neuroscience: Icahn School of Medicine at Mount Sinai, Department of Psychiatry and Psychotherapy: University of Tübingen, Department of Radiology: Washington University School of Medicine, Departments of Medicine Biomedicine and Clinical Research: University Hospital Basel, Division of Biostatistics: Washington University School of Medicine, Dominantly Inherited Alzheimer Network, Dominantly Inherited Alzheimer Network (DIAN), Dominantly Inherited Alzheimer's Disease, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Edith Cowan University: Western Australia, Florey Institute of Neuroscience and Mental Health: University of Melbourne, German Center for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Germany, Harvard Medical School, Hereditary Alzheimer's Disease, Hertie Institute for Clinical Brain Research, Icahn School of Medicine at Mount Sinai (New York), Indiana Alzheimer Disease Center and Department of Pathology and Laboratory Medicine: Indiana University School of Medicine, Indiana University School of Medicine, Ludwig-Maximilians-Universität München, Macquarie University, Macquarie University (New South Wales), Massachusetts General Hospital, National Institute on Aging, National Institute on Aging (NIA), National Institute on Aging (US), Nature Medicine, Neurodegeneration Division: The Florey Institute of Neuroscience and Mental Health, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurofilament Light Chain (NfC), Neurofilament Light Chain (NFL), Neurofilament Light Protein (NF-L), Neurofilament Light Protein in Blood: Potential Biomarker of Neurodegeneration, Neurologic Clinic and Policlinic: University Hospital Basel, Neuroscience Research Australia, Non-Invasive Biomarkers, Plasma Biomarkers, Preclinical Alzheimer's Disease, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, School of Medical Health and Sciences: Edith Cowan University, School of Medical Sciences: University of New South Wales, Serum Neurofilament Light Chain Protein, Switzerland, Taub Institute for Research on Alzheimer's Disease and the Aging Brain: Columbia University Medical Center, United States, University College London, University Hospital Basel, University of Basel, University of Melbourne, University of New South Wales, University of Tübingen, US National Institute on Aging, USA, Warren Alpert Medical School of Brown University, Washington University School of Medicine | Leave a comment

Further Evidence on the Association Between Poor Oral Health and the Risk of Developing Alzheimer’s Disease. New Possibilities for Treatment? (BBC News / Science Advances)

Posted on January 25, 2019 by Dementia and Elderly Care News

Summary Analysis of brain tissue, spinal fluid, and saliva from persons with Alzheimer’s Disease indicates the presence of Porphyromonas gingivalis (the bacterium associated with chronic gum disease) in the brain and central nervous system. Animal research using mice indicates that … Continue reading →

Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Alzheimer's Disease and Chronic Periodontitis, Alzheimer's Disease Causation and Possible Treatments, Alzheimer’s Disease, Amyloid Beta, Amyloid Beta Protein, Arginine-Gingipain A (RgpA), Arginine-Gingipain B (RgpB), Australia, Bazian, Behind the Headlines, Beta-Amyloid Plaques, Chronic Gum Disease, Chronic Periodontitis, Common Oral Problems and Risk Factors, COR271, COR388, Cortexyme, Dementia Risk Factors, Dental Healthcare, Dental Hygiene, Evidence for Risk Factors of Dementia, Gingipain, Gingipain Inhibitors, Gum Disease, Gum Disease (Periodontitis), Gum Disease Bacteria, Harvard University School of Dental Medicine, β-Amyloid Plaques, Jagiellonian University (Poland), Lysine-Gingipain (Kgp), Mice, Modifiable Risk Factors, Neuroprotective Agents, New Zealand, Oral Health in Older Adults, Oral Healthcare, Oral Hygiene, P. gingivalis, Periodontitis, Periodontitis and Risk of Developing Alzheimer’s Disease, Poland, Porphyromonas gingivalis, Porphyromonas Gingivalis in Alzheimer’s Disease, Risk Factors, Science Advances (Journal), Small-Molecule Gingipain Inhibitors: Possibly Neuroprotective, Tau Tangles, Transgenic Mice, University of Auckland, University of California, University of Louisville School of Dentistry, University of Melbourne | Leave a comment

The Health Benefits of Fibre (BBC News / Lancet)

Posted on January 14, 2019 by Dementia and Elderly Care News

Summary A systematic review and meta-analysis of previous studies indicates that consumption of dietary fibre (roughage) confers many health benefits. Comparison of health outcomes between the highest consumers of dietary fibre (versus the lowest) suggests that there is between 15-30% … Continue reading →

Posted in BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Scotland, Statistics, Systematic Reviews, Universal Interest | Tagged Balanced Diet, BBC Health News, Carbohydrate Quality, Department of Human Nutrition: University of Otago, Department of Medicine: Riddet Centre of Research Excellence, Department of Medicine: University of Otago, Diet and Mortality, Diet and Nutrition, Diet-Related Ill Health, Dietary Factors, Dietary Fibre, Dietary Glycaemic Index, Dundee, Edgar National Centre for Diabetes and Obesity Research: University of Otago, Epidemiology, Epidemiology and Statistics, Healthier Lives National Science Challenge (New Zealand), Healthy Ageing, Healthy Behaviour, Healthy Diet, Healthy Eating, Healthy Lifestyles, Lancet, Mortality Statistics, New Zealand, Non-Communicable Diseases (NCD), Nutrition, Nutritional and Metabolic Disorders, Poor Diets, Refined Grains, Riddet Centre of Research Excellence (New Zealand), Roughage, School of Medicine: University of Dundee, Scotland, Systematic Reviews and Meta-Analyses, University of Dundee, University of Otago, Whole Grains | Leave a comment

Antidepressants Not Recommended for Depression in People With Dementia (NIHR Signal / Cochrane Database)

Posted on January 12, 2019 by Dementia and Elderly Care News

Summary A National Institute for Health Research “Signal” expert commentary refers to a systematic review which indicates that antidepressants are unsuitable / unhelpful for the treatment of depression in persons living with dementia. Full Text Link Reference Antidepressants do not … Continue reading →

Posted in Acute Hospitals, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, NIHR, Person-Centred Care, Pharmacological Treatments, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged Addenbrooke), Addenbrookes Hospital, Adverse Effects, Adverse Events, ALOIS: a Comprehensive Register of Dementia Studies, ALOIS: Cochrane Dementia and Cognitive Improvement's Specialized Register, ALOIS: the Cochrane Dementia and Cognitive Improvement Group, Antidepressants, Antidepressants for Agitation and Psychosis in Dementia, Antidepressants for Depression in Dementia, Antidepressants for Treating Depression in Dementia, Cambridge and Peterborough NHS Foundation Trust, Cambridge University Hospitals (Addenbrooke’s), Cochrane Database, Cochrane Database of Systematic Reviews, Cochrane Dementia and Cognitive Impairment Group, Cochrane UK, Department of Psychiatry: University of Cambridge, Drug Side-Effects, Inappropriate Medication, Inappropriate Prescribing, Later Life, Mental Health and Illness, National Institute for Health Research Signal, National Perinatal Epidemiology Unit (NPEU): University of Oxford, NIHR Signal, Older People’s Mental Health Service: Cambridge and Peterborough NHS Foundation Trust, Oxford Health NHS Foundation Trust, Potentially Inappropriate Medications (PIM), Potentially Inappropriate Prescribing, Potentially Inappropriate Prescribing (PIP), Potentially Inappropriate Prescribing in Depression and Dementia, Preventable Adverse Events, Professor Martin Orrell, Professor Martin Orrell: Director of Institute of Mental Health at University of Nottingham; Division of Psychiatry and Applied Psychology: University of Nottingham, Psychotropic Drug Use (Antipsychotics Antidepressants Hypnotics Anxiolytics Anticonvulsants Antidementia Drugs), Reducing Inappropriate Prescribing of Antidepressants, Selective Serotonin Reuptake Inhibitors (SSRIs), University of Cambridge, University of Nottingham, University of Oxford | Leave a comment

French Research Into the Needs of Carers for People With Neurocognitive Disorders (BMC Health Services Research)

Posted on January 8, 2019 by Dementia and Elderly Care News

Summary This review investigated aspects of the additional burdens for carers typically arising from caring for persons with neurocognitive disorders, with a view to developing a consensus on the priorities of caregivers. An expert panel was consulted, comprising 68 informal carers of … Continue reading →

Posted in Community Care, For Carers (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), International, Management of Condition, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest | Tagged Advice and Support, Aggression, Agitation, Awareness of Confusion and Dementia, Being Understood During a Conversation, Burden on Caregivers, Caregiver Distress, Caregiving (Carers), Carer Fatigue, Carer Support, Carers, Carers for People with Dementia, Challenges in Communication, Challenging Behaviour, Challenging Behaviour in Dementia, Charpennes Hospital: Hospices Civils de Lyon, Clinical and Research Memory Centre of Lyon (CMRR): Charpennes Hospital, Cognitive Impairment, Communicating With the Person, Communication Skills, Coping Strategies, Coping With Behavioural Disorders, Coping With Cognitive Disorders, Coping With Stress, Demands of Caring, Department of Internal Medicine: University of Geneva, Expert Consensus Guidelines for Family and Carers, Family Caregivers, Family Carers, Finding Available Services close to Home, France, Health Services and Performance Research: University Lyon, Hospices Civils de Lyon, Impact of Caring on Carers, Improving Carer Health and Wellbeing, Improving Lives of Carers, Information and Advice, Information and Signposting Services, Information Needs of Carers, Information on Caregiver Health, Information on Cognitive Disorders, Information on Comorbidities, Information on Drugs, Information on Neurocognitive Diseases and Progression, Information on non-Pharmacological Treatments, Information on Providing Emotional and Affective Support, Information on Roles of Health Professionals, INSERM U1028, Lyon (France), Lyon Neuroscience Research Center: Brain Dynamics and Cognition Team (INSERM), Making Decisions and Planning For the Future, Management of Challenging Behaviour, Pharmaceutical Unit: Hospices Civils de Lyon, Rehabilitation and Geriatrics: University Hospitals of Geneva, Seeing the Person Behind the Dementia, Seeking Professional Help, Shared Decision-Making, Signposting Patient Information, Signposting Services and Knowledge, Signposting to Appropriate Health Services, Signposting to Local Community Services, Signposting to Sources of Practical Help, Stimulating Appropriates Activities, Strategies For Managing Resistance, Stress Reduction, Stress Reduction for Unpaid Family Carers, Support for Carers, Supporting Persons With Dementia, Sustainable Caring, Switzerland, Talking To the Person, University Hospitals of Geneva, University Lyon, University of Geneva, Unpaid Caregivers (Carers), Unpaid Carers | Leave a comment

Blueprint for Complex Care: Care for Individuals with Complex Health and Social Needs (National Center for Complex Health and Social Needs / IHI / Duke University / NIHR)

Posted on December 29, 2018 by Dementia and Elderly Care News

Summary The latest Institute for Healthcare Improvement (IHI) report covers multi-disciplinary and multi-agency approaches to better coordination in the provision of care for individuals with complex health and social needs, from a USA perspective. “The Blueprint for Complex Care is a joint … Continue reading →

Posted in Commissioning, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Health Foundation, Integrated Care, International, Local Interest, Management of Condition, Non-Pharmacological Treatments, Person-Centred Care, Quick Insights, Royal Wolverhampton NHS Trust, Standards, Universal Interest, Wolverhampton | Tagged Accountable Care Organisations (ACOs), Accountable Care Organisations (in United States and England), Accountable Health Communities, Adult Social Care for People with Complex Needs, Advancing Integrated Care in England: Practical Path for Care Transformation, Ageing Population, Barriers to Integrated Care, Barriers to Integration, Barriers to Integration: Different Funding Models, Barriers to Integration: Different Workforce Cultures, Barriers to Integration: Difficulties in Effective Information Sharing, Barriers to Integration: Organisational Integration, Blueprint for Complex Care, Bridgespan Group: Strong Field Framework, Camden Coalition of Healthcare Providers (CCHP), Care of Frail Older People With Complex Needs, Center for Health Care Strategies, Center for Medicare and Medicaid Innovation (CMMI), Commonwealth Fund, Community Outreach, Complex Care, Complex Care and Multimorbidity, Complex Care Champions, Complex Care Ecosystem, Complex Chronic Conditions, Complex Comorbidities, Complex Conditions, Complex Needs, Complex Patients at Risk of Hospital Admission, Conceptual Model: Starter Taxonomy for High-Need Patients, Cross-Sector Partnerships, Data Sharing, Data Sharing for Better Health, Dr Robin Miller: Deputy Director of Health Services Management Centre at University of Birmingham, Duke University, Duke-Margolis Center for Health Policy, Effective Care for High Need Patients: National Academy of Medicine (NAM) Report, Global Health Innovation Center: Duke University, Health Care Innovation Awards, Health Services Management Centre (HSMC): University of Birmingham, Health Services Management Centre: University of Birmingham, HSMC: University of Birmingham, IHI: Institute for Healthcare Improvement, Innovation Accelerator Program, Institute for Healthcare Improvement, Institute for Healthcare Improvement (IHI), Integrated Care Partnerships and Accountable Care Organisations, Integrated Multi-Agency Care, Lived Experience, Medication Management, Multi-Agency Collaboration, Multi-Agency Integration, Multi-Agency Working, Multi-Disciplinary and Multi-Agency Working, National Center for Complex Health and Social Needs, National Institute for Health Research (NIHR), National Institute for Health Research Health Services and Delivery Research Programme, National Institute for Health Research Signal, NIHR Signal, Organisational Competencies to Accelerate Care Improvements, Outreach Services, Quality Improvement, Quality Measures, Robert and Lisa Margolis Family Foundation, Robert Wood Johnson Foundation, Robert Wood Johnson Foundation (RWJF), SCAN Foundation, School of Health and Related Research (ScHARR): University of Sheffield, Strong Field Framework, United States, University of Sheffield, USA, Value-Based Payments (VBP), Variability in Implementation (of Integrated Care), Vertical Integration, Vertical Integration (of Primary and Secondary Care) | Leave a comment

Category Archives: International

Pseudomedicine and Potential Dementia Treatments? (JAMA)

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Further Evidence on the Association Between Poor Oral Health and the Risk of Developing Alzheimer’s Disease. New Possibilities for Treatment? (BBC News / Science Advances)

Antidepressants Not Recommended for Depression in People With Dementia (NIHR Signal / Cochrane Database)

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