Category Archives: Parkinson’s Disease

Parkinson’s Disease.

Medicine to Ease Enlarged Prostate Re-Purposed for Parkinson’s Disease? (BBC News / Journal of Clinical Investigation)

Posted on September 20, 2019 by Dementia and Elderly Care News

Summary Terazosin, a drug developed originally to treat benign prostatic hyperplasia (BPH), may slow the progression of Parkinson’s Disease. It is thought that Terazosin may help by activating an enzyme (PGK1) which prevents cell death in the relevant brain regions. … Continue reading →

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Parkinson's Disease, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged BBC Health News, Beihang University (Beijing), Beijing Advanced Innovation Center for Big Data-Based Precision Medicine: Beihang University, Beijing Institute for Brain Disorders: Capital Medical University, Bellvitge University Hospital-IDIBEL, Benign Prostatic Hyperplasia (BPH), Capital Medical University (Beijing), Carver College of Medicine: University of Iowa, Center of Regenerative Medicine in Barcelona (CMRB), Center of Stroke: Beijing Institute for Brain Disorders, China, Department of Molecular and Translational Medicine: University of Brescia, Department of Pathology and Experimental Therapeutics: Bellvitge University Hospital-IDIBELL, Departments of Pharmaceutical Care and Neurology: University of Iowa, Disease-Modifying Treatments for Parkinson's Disease, Drugs Development and Re-Purposing, Hospital Duran i Reynals, Hospitalet de Llobregat (Barcelona), Hospitalet de Llobregat and Institute of Biomedicine of the University of Barcelona (IBUB), Howard Hughes Medical Institute: University of Iowa, Institució Catalana de Recerca i Estudis Avançats (ICREA), Institute of Hypoxia Medicine: Xuanwu Hospital, Italy, Journal of Clinical Investigation, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education (China), Loss of Dopaminergic Neurons in pars compacta of Substantia Nigra (SNpc), Networking Biomedical Research Center in Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Neurodegenerative Disorders, Neurodegenerative Research, Off-Label Drug Repurposing Trials, Peking University, PGK1, Phosphoglycerate Kinase 1 (PGK1), Potential Repurposing of Drugs to Slow Progression of Parkinson’s Disease, Repurposing of Drugs, School of Life Sciences: Peking University, Spain, State Key Laboratory of Membrane Biology: Peking University, Substantia Nigra, Terazosin, United States, University of Brescia, University of Iowa, USA, Xuanwu Hospital (China) | Leave a comment

Advancing Population Health: Government Consulation on Personalised Medicine and Prevention for the 2020s (BBC News / Cabinet Office / DHSC)

Posted on July 28, 2019 by Dementia and Elderly Care News

Summary It is expected that, by the 2020s, technological advances including genomics and artificial intelligence (AI) will massively improve “proactive, predictive, and personalised” approaches to the prevention of ill health. A wide-ranging consultation document explains many of the options, opportunities … Continue reading →

Posted in Assistive Technology, BBC News, Commissioning, Community Care, Department of Health, Department of Health and Social Care (DHSC), Depression, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Integrated Care, Management of Condition, Mental Health, National, NHS, Non-Pharmacological Treatments, Parkinson's Disease, Person-Centred Care, Personalisation, Public Health England, Quick Insights, Standards, UK, Universal Interest | Tagged Accelerating Detection of Disease (ADD) Challenge, Accelerating Detection of Disease Programme, Accelerating Detection of Disease Projects, Active Ageing, Active Lifestyle, Active Play, Active Travel, Adapting Homes and Neighbourhoods, Adult Social Care: £7.5 Million for Research to Improve Care Delivery, Advanced Pain Discovery Platform, Advanced Pain Discovery Platform: Mapping the Complexity of Chronic Pain, Advancing Our Health: Prevention in the 2020s (DHSC 2019 Consultation), Advancing our Health: Prevention in the 2020s (Green Paper), Age-Friendly Environments, Ageing Population, Ageing Society, Ageing Society Grand Challenge, Air Quality Expert Group (AQEG), Alcohol Abuse, Alcohol Care Teams, Alcohol Misuse, Anti-Smoking Legislation, Anxiety, Asset-Based Approaches, Asset-Based Approaches to Health and Wellbeing, Baroness Blackwood, BBC Devon News, Biotechnology and Biological Science Research Council (BBSRC), Broad Determinants of Health, Cabinet Office, Centres of Excellence in Digital Pathology and Imaging, Changing Behaviours in Public Health, Changing Places Toilets, Childhood Obesity Strategy, Childhood Obesity Strategy (Chapter 3), Children’s Oral Health, Cigarette Smoking, Clean Air Strategy, Committee on the Medical Effects of Air Pollutants (COMEAP), Community Pharmacies, Composite Health Index, Comprehensive Model for Personalised Care, Connected Society: Strategy for Tackling Loneliness (2018), 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BBC Health News, Smoke-Free 2030 Ambition, Smoking Cessation, Social Determinants of Health, Social Determinants of Health Inequalities, Social Gradient in Healthy Life Expectancy, Social Gradient in Life Expectancy, Social Prescribing, Social Prescribing Academy, Societal Determinants of Health, Socio-Environmental Risk Factors, Southwark Digital Health Check Tool, Staying Put, Stevenson / Farmer Review of Mental Health and Employers (Thriving at Work), Strategic Priorities Fund (SPF), Supporting Self-Care, Tackling Causes of Preventable Ill Health, Tackling Multimorbidity at Scale, Tackling Multimorbidity at Scale: Unpicking Disease Clustering Biological Pathways and Trajectories, Tailored (“Personalised”) Lifestyle Advice, Targeted (“Personalised”) Support, Thrive Bristol, Thriving at Work: the Stevenson / Farmer Review of Mental Health and Employers, Tobacco Cessation, Tobacco Consumption, Transformational Technologies, Transformative Health Technology, Transformative Technology, Transforming Children and Young People's Mental Health Provision, UK Biobank, UK Centre of Evidence Implementation in Adult Social Care, UK Centre of Evidence Implementation in Adult Social Care (ESRC), UK National Screening Committee (UK NSC), UK Research and Innovation (UKRI), Value for Money, Versus Arthritis, West Midlands Violence Prevention Alliance, Whole Genome Sequencing (WGS), Wider Determinants of Health, Wider Determinants of Mental Health, Wigan Deal: Adult Social Care and Wellbeing, World-Class Research | Leave a comment

Spinal Implants May Revolutionise Walking Rehabilitation in Parkinson’s Disease? (BBC News / Parkinson’s UK)

Posted on April 24, 2019 by Dementia and Elderly Care News

Summary Canadian researchers working with electrical stimulation to the spines of chronic Parkinson’s Disease patients have discovered a technique to improve mobility and reduce the risk of falls. The implants improve feedback signals returning back up to the brain. “[Benefit … Continue reading →

Posted in BBC News, Charitable Bodies, Falls, Falls Prevention, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Non-Pharmacological Treatments, Parkinson's Disease, Person-Centred Care, Quick Insights, UK, Universal Interest | Tagged BBC Health News, BBC Science and Environment News, Canada, Department of Clinical Neurological Sciences: Lawson Health Research Institute, Dorsal Spinal Cord Stimulation, Freezing, Freezing in Parkinson’s Disease, Freezing of Gait Questionnaire (FOG‐Q), Gait Disorder, Gait Disorders, Gait Dysfunction in Advanced Parkinson's Disease Patients, Improving Gait, International Parkinson and Movement Disorder Society, Lawson Health Research Institute (London Ontario), London Health Sciences Centre: Lawson Health Research Institute, Movement Disorders, Movement Disorders (Journal), Novel Rehabilitation Therapy, Parkinson’s UK, Parkinson’s UK (Parkinsons Disease Society), Protokinetics Walkway, Rehabilitation and Parkinson’s Disease, Rehabilitation Therapy, Schulich School of Medicine and Dentistry: University of Western Ontario, Spinal Cord Stimulation, Spinal Cord Stimulation Therapy for Gait Dysfunction in Advanced Parkinson's Disease, Spinal Stimulation to Improve Mobility in Parkinson's Disease, Spinal Stimulation to Improve Walking in Parkinson's Disease, Spinal Stimulation to Reduce Falls in Parkinson's Disease, Spinal Stimulation to Reduce Freezing in Parkinson's Disease, Unified Parkinson's Disease Rating Scale (UPDRS), University of Western Ontario, UPDRS Motor Items and Activities‐Specific Balance Confidence Scale, Walking Pattern (Gait), Western University (Ontario) | Leave a comment

Non-Pharmacological Treatments for Lewy Body Dementia (Psychological Medicine / International Psychogeriatrics)

Posted on April 16, 2019 by Dementia and Elderly Care News

Summary Lewy Body Dementia (dementia with Lewy bodies and Parkinson’s Disease Dementia) involves visual hallucinations, fluctuating cognition / attention, motor disturbances, falls, and extreme sensitivity to antipsychotics. Caution in the use of pharmacological treatments such as antipsychotics is advised in … Continue reading →

Posted in Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Parkinson's Disease, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged Adverse Sensitivity to Neuroleptics, Antipsychotic Sensitivity Reactions, Antipsychotics: Neuroleptic Sensitivity, Aspiration of Fluids in Patients With Dysphagia, Australia, Bethlem Royal Hospital, Carer Education, Deep Brain Stimulation (DBS), Deep Brain Stimulation (DBS) of Nucleus Basalis of Meynert (NBM) in Dementia with Lewy Bodies (DLB), Dementia Centre for Research Collaboration: UNSW Sydney, Dementia with Lewy Bodies, Dementia With Lewy Bodies (DLB), Department of Old Age Psychiatry: King's College London, Department of Psychiatry: University of Cambridge, Electroconvulsive Therapy (ECT), Environmental Modifications, Exercise for Dementia, Fluctuating Cognition, Guy's Hospital: King's College London, Improving Gait, Institute of Health and Society: Newcastle University, Institute of Neuroscience: Newcastle University, Institute of Psychiatry Psychology and Neuroscience: King’s College London, International Psychogeriatrics, Kings College London, Lee Silverman Voice Treatment, Lee Silverman Voice Treatment (LSVT), Lewy Body Dementia, Lewy Body Dementia (LBD), Mirrored Self-Misidentification Delusion, Music Therapy, Music Therapy and Dementia, Music Therapy for BPSD, Newcastle University, Non-Motor Fluctuations in Parkinson's Disease, Non-Pharmacological Treatments for Lewy Body Dementia, Occupational Therapy, Parkinson’s Disease Dementia, Parkinson’s Disease Dementia (PDD), Physical Therapy (Lee Silverman Voice Treatment), Prevention of Fluids Aspiration in Patients With Dysphagia, Psychological Medicine (Journal), Severe Antipsychotic Sensitivity Reactions, Severe Neuroleptic Sensitivity, Severe Sensitivity to Antipsychotic Agents, Simulated Presence, Simulated Presence Therapy (SPT), Simulated Presence Therapy for BPSD, South London and Maudsley NHS Foundation Trust, Sydney Medical School: University of Sydney, Task-Oriented Motor Practice, Transcranial Direct Current Stimulation, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation (TMS), Treatments for Dementia With Lewy Bodies and Parkinson's Disease Dementia, University of Cambridge, University of New South Wales (UNSW), University of Sydney, UNSW Sydney, Visual Hallucinations, Walking Pattern (Gait) | Leave a comment

Smell Test for Early Detection of Parkinson’s Disease (BBC News)

Posted on March 21, 2019 by Dementia and Elderly Care News

Summary Parkinson’s Disease has a distinctive odour for certain gifted individuals, which has been analysed chemically and may now be replicated for automated detection by machine. This may, in future, permit earlier diagnosis and open the possibilities for timely treatments … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, Scotland, UK, Universal Interest | Tagged ACS Central Science (Journal), Anatune (Cambridge UK), BBC Health News, BBC Scotland News, Biomarkers, Biomarkers Predicting Parkinson's Disease, Department of Biochemistry: University of Liverpool, Department of Neurology: Salford Royal Foundation Trust, Early Diagnosis, Early Diagnosis of Parkinson’s Disease, Edinburgh University, Eicosane, Hyperosmic Super Smeller, Institute for Stem Cell Research: University of Edinburgh, Institute of Integrative Biology: University of Liverpool, Joy Milne, Les Milne, Manchester Academic Health Science Centre: University of Manchester, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Non-Invasive Biomarkers, Odour, Parkinson's Disease Smell Test, Parkinson’s Disease Sebum Volatilome, Parkinson’s UK, Perillic Aldehyde, Rapid Screening, Salford Royal Foundation Trust, School of Biological Sciences: University of Edinburgh, Sebum, Smell Test for Parkinson's Disease Diagnosis, Timely / Preclinical Parkinson's Disease Diagnosis, Timely Diagnosis, University of Edinburgh, University of Liverpool, University of Manchester, Volatile Biomarkers of Parkinson’s Disease, Volatilome | Leave a comment

Further Research Supports Speculation of Link Between Gut and Parkinson’s Disease (BBC News / Science Translational Medicine)

Posted on November 2, 2018 by Dementia and Elderly Care News

Summary Further evidence implying that the gut may be involved in the development of Parkinson’s Disease has emerged. Toxic (alpha-synuclein) proteins associated with Parkinson’s Disease tend to accumulate in the appendix, and it seems that people who have had their … Continue reading →

Posted in BBC News, For Doctors (mostly), For Researchers (mostly), In the News, International, Parkinson's Disease, Quick Insights, Universal Interest | Tagged Abnormal Proteins (Alpha-Synuclein), Alpha-Synuclein Aggregation, Alpha-Synucleinopathies, Appendectomy Associated With Delayed Age of Parkinson’s Disease, Appendectomy Associated With Lower Risk of Parkinson’s Disease, Appendix Contains Truncated α-synuclein Proteoforms, Appendix Lysates, BBC Health News, Benefits of Missing Appendix, Canada, Center for Neurodegenerative Science: Van Andel Research Institute, Centre for Addiction and Mental Health (Toronto), Centre National de la Recherche Scientifique Gif sur Yvette, College of Human Medicine: Michigan State University, Department of Clinical Sciences Psychiatry: Lund University, Department of Epidemiology and Biostatistics: Michigan State University, Epidemiology, Epidemiology and Statistics, Faculty of Medicine: Lund University, France, Healthy Human Appendix Contains α-synuclein, Human Gut (Appendix): a Potential Risk Factor for Parkinson's Disease, α-Synuclein, α-Synuclein Aggregation, Lund University, Michigan State University, Northwestern University (Evanston), Paris-Saclay Institute of Neuroscience: Centre National de la Recherche Scientifique, Parkinson’s Disease Pathogenesis, Parkinson’s Disease Risk and Appendix (Gut), Parkinson’s Progression Markers Initiative (PPMI), Prodromal Parkinson's Disease, Proteomics Center of Excellence: Northwestern University, Psychiatric Clinic (Lund), Risk Factors, Risk Factors for Parkinson's Disease, Science Translational Medicine, Statistics Sweden, Sweden, Swedish National Patient Registry (SNPR), Synucleinopathy Progression, United States, USA, Van Andel Research Institute, Vermiform Appendix, Vermiform Appendix and Risk of Parkinson’s Disease | Leave a comment

Doubling in Global Burden of Parkinson’s Disease, 1990–2016 (Lancet Neurology)

Posted on October 3, 2018 by Dementia and Elderly Care News

Summary A systematic analysis of epidemiological studies concerning the global, regional, and nation-specific prevalence of Parkinson’s Disease (and years of life lived with disability arising from this condition) notes a doubling of the burden of Parkinson’s Disease between 1990 and … Continue reading →

Posted in For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Parkinson's Disease, Quick Insights, Statistics, Systematic Reviews, Universal Interest | Tagged Country-Specific Burden(s) of Parkinson’s Disease (1990–2016), Deaths Prevalence and DALYs for Parkinson's Disease in 2016, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Epidemiology of Parkinson's Disease, GBD 2016 Parkinson's Disease Collaborators, Global Burden of Disease (GBD), Global Burden of Disease Regions, Global Burden of Disease Study (GBD), Global Burden of Parkinson’s Disease (1990–2016), Global Health Data Exchange, Global YLD and YLL Rates Per 100000 Population for Parkinson's Disease by age in 2016, Institute for Health Metrics and Evaluation, Lancet Neurology, Lifestyle Risk Factors, Neurological Disorders, Parkinson's, Prevalence of Neurological Disorders, Prevalence of Parkinson's Disease, Regional Burden of Parkinson’s Disease (1990–2016), Risk Factors for Parkinson's Disease, Socio-Environmental Risk Factors, Worldwide Prevalence and Incidence of Parkinson's Disease, Years Lived With Disability (YLD) for Parkinson's Disease, Years of Life Lost (YLLs), YLLs | Leave a comment

Category Archives: Parkinson’s Disease

Medicine to Ease Enlarged Prostate Re-Purposed for Parkinson’s Disease? (BBC News / Journal of Clinical Investigation)

Spinal Implants May Revolutionise Walking Rehabilitation in Parkinson’s Disease? (BBC News / Parkinson’s UK)

Non-Pharmacological Treatments for Lewy Body Dementia (Psychological Medicine / International Psychogeriatrics)

Smell Test for Early Detection of Parkinson’s Disease (BBC News)

Further Research Supports Speculation of Link Between Gut and Parkinson’s Disease (BBC News / Science Translational Medicine)

Doubling in Global Burden of Parkinson’s Disease, 1990–2016 (Lancet Neurology)

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