Category Archives: Pharmacological Treatments

Cognitive Symptoms of Alzheimer’s Disease: Management and Prevention? (BMJ)

Summary A review investigates pharmacological treatments for cognitive symptoms in Alzheimer’s Disease at different phases in progression of the disease, in the context of the paucity of effective disease-modifying interventions. Discrepancies between different national and international guidelines, regarding the prescription … Continue reading

Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Optimal Timing of Blood Pressure Medication: Insight Into Chronotherapy for Cardiovascular Disease Risk Reduction (BBC News / EHJ / Bazian)

Summary Results from the Hygia Chronotherapy Trial suggest that blood pressure medicines may be more effective at lowering blood pressure, and reducing the risk of heart attacks and / or stroke, when taken at bedtime. Full Text Link Reference Roberts, M. (2019). Blood … Continue reading

Posted in BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Hypertension, In the News, International, Management of Condition, NHS Digital (Previously NHS Choices), Person-Centred Care, Pharmacological Treatments, Quick Insights, Stroke, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Biogen’s Aducanumab: Possibly the First Viable Drug Treatment of Alzheimer’s Disease? (BBC News)

Summary There were early hopes that the drug Aducanumab (from Biogen) might be able to slow down the build-up of amyloid protein in the brain, but trials were halted in March 2019 due to “disappointing” trial results. Subsequent re-analysis of … Continue reading

Posted in BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Person-Centred Care, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Quality Improvement: Strategies Needed to Reduce Preventable Patient Harm (NIHR Signal / BMJ / Future Healthcare Journal / WHO)

Summary A recent review found that around 6% patients in healthcare settings (internationally) experience potentially preventable harm; with approximately 1 in 8 such cases resulting in severe harm, permanent disability or death​ “Six types of patient harm were identified: drug … Continue reading

Posted in Acute Hospitals, Commissioning, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, International, NHS, NHS England, NHS Improvement, NIHR, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Royal Wolverhampton NHS Trust, Systematic Reviews, UK, Universal Interest, World Health Organization (WHO) | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Holistic Consideration of Apathy in Dementia (Journal of the American Geriatrics Society)

Summary A recent review of apathy proposes an integrative (holistic) model for understanding the condition, in common with other forms of BPSD. “As with other BPSD, …neural mechanisms alone do not completely account for the syndrome – individual, caregiver and … Continue reading

Posted in Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, International, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

More on the The Lancet Commission on Dementia Prevention, Intervention, and Care (Irish Journal of Psychological Medicine / Lancet)

Summary The Lancet Commission on Dementia Prevention, Intervention, and Care has produced recommendations for the prevention of dementia, proposing a “life-course model of dementia prevention” incorporating nine modifiable risk factors for reducing the risk of dementia. The commission also offers recommendations about the pharmacological, … Continue reading

Posted in Alzheimer's Society, Alzheimer’s Research UK, Charitable Bodies, Commissioning, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, Management of Condition, National, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Medicine to Ease Enlarged Prostate Re-Purposed for Parkinson’s Disease? (BBC News / Journal of Clinical Investigation)

Summary Terazosin, a drug developed originally to treat benign prostatic hyperplasia (BPH), may slow the progression of Parkinson’s Disease. It is thought that Terazosin may help by activating an enzyme (PGK1) which prevents cell death in the relevant brain regions. … Continue reading

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Parkinson's Disease, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment