Category Archives: Pharmacological Treatments

Vitamin E and / or Selenium for Dementia Prevention? (JAMA Neurology)

Summary The Prevention of Alzheimer’s Disease by Vitamin E and Selenium (PREADViSE) trial investigated the potential use of antioxidant supplementation (whether Vitamin E and / or selenium) for the prevention of dementia in asymptomatic older men. This study has now … Continue reading

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Dementia-Friendly Community Pharmacies (Greater Manchester Pharmacy LPN / RPS)

Summary The Greater Manchester Pharmacy Local Professional Network have produced a brief guide on the seven elements of good practice: The pharmacy environment. The pharmacy team. Public health messages, including lifestyle. Over the counter medicines. Prescription ordering and collection / … Continue reading

Posted in Commissioning, Community Care, For Nurses and Therapists (mostly), Integrated Care, Management of Condition, Mental Health, Models of Dementia Care, Person-Centred Care, Pharmacological Treatments, Quick Insights, Standards, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

The Reproducibilty Problem / Replication Crisis in Science: a Pervasive Issue in Medicine? (BBC News / Nature / Elife)

Summary It has been estimated that between 65% and 90% of researchers typically fail to reproduce fellow scientists’ research results. The Reproducibility Project: Cancer Biology has raised awareness of the prevalence of this problem in biomedical science. The issues are … Continue reading

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Elderly Major Trauma Patients: Guidelines (London Major Trauma System / Emergency Medicine Journal)

Summary The 11.5 million people aged 65 and older is the fastest growing age group in the UK They comprise 18% of the population today, and this figure is projected to rise to 25% of the population by 2040. According … Continue reading

Posted in Acute Hospitals, Commissioning, Falls, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Hip Fractures, In the News, Integrated Care, Management of Condition, National, NHS, NHS England, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Standards, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Proton Pump Inhibitors Increase the Risk of Dementia? (NHS Choices / JAMA Neurology)

Summary One of NHS Choices, Behind the Headlines‘ “Top News Stories of 2016”. It appears that people using proton pump inhibitors (PPIs) may have a 44% higher risk of developing dementia over a seven-year period. “This finding is supported by … Continue reading

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BBC iWonder Guide: How Close Are We to Stopping Alzheimer’s Disease? (BBC News)

Summary The BBC’s iWonder Guides provide “thought-provoking answers to the questions sparked by everyday life”. This particular collection of brief digestible articles, animations and videos covers: A frightening prospect (epidemiological statistics). How the disease affects your brain cells (an interactive … Continue reading

Posted in Animal Studies, BBC News, In the News, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Statistics, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Another Recent Alzheimer’s Disease Drug Trial Disappointment (Lancet)

Summary Researchers aimed to discover whether LMTM [Leuco-methylthioninium bis(hydromethanesulfonate] might be safe and effective for slowing disease progression in patients with mild to moderate Alzheimer’s Disease. LMTM had previously been found to work as a selective inhibitor of tau protein … Continue reading

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