Category Archives: Animal Studies

Animal Studies

Potential Relationship Between Vitamin A Deficiency and Alzheimer’s Disease Risk? (NHS Choices / Acta Neuropathologica)

Summary NHS Choices’ Behind the Headlines covers Chinese and Canadian research, based on both humans and animals, indicating potential associations between Vitamin A deficiency and later development of Alzheimer’s Disease. “ …vitamin A deficiency is a problem in the developing … Continue reading

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Flashing Light: A Potential Alternative to Drug Treatment to Prevent Amyloid Plaque Formation? (BBC News / Nature)

Summary Animal research on genetically modified mice suggests that a specialised form of flashing light therapy might help slow the progression of Alzheimer’s Disease. It appears that shining a strobe light, flashing at a rate of 40Hz, into rodents’ eyes … Continue reading

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Possibly a Paradigm Shift in the Understanding of Parkinson’s Disease? (BBC News / Cell / NHS Choices)

Summary Animal research in the United States and Sweden suggests that Parkinson’s Disease may be caused by bacteria living in the gut. It appears likely that the certain gut bacteria (the “gut microbiome”) could be responsible for releasing chemicals (SCFAs) … Continue reading

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BBC iWonder Guide: How Close Are We to Stopping Alzheimer’s Disease? (BBC News)

Summary The BBC’s iWonder Guides provide “thought-provoking answers to the questions sparked by everyday life”. This particular collection of brief digestible articles, animations and videos covers: A frightening prospect (epidemiological statistics). How the disease affects your brain cells (an interactive … Continue reading

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Early Promising Signs in Verubecestat Human Drug Trial (NHS Choices / Science Translational Medicine / Translational Neurodegeneration)

Summary Early results from a Phase I trial indicate that the BACE1 inhibitor Verubecestat may effectively reduce β-amyloid formation in human patients with Alzheimer’s Disease. This appears to confirm previous trials with rats, monkeys and healthy young human adults. As … Continue reading

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Earlier Diagnosis of Parkinson’s Disease? (BBC News / Acta Neuropathologica Communications)

Summary Recent animal research, using rats, suggests there may be a cheap and non-invasive method of detecting Parkinson’s Disease early – before symptoms develop – by identifying changes in the eye. The same study also offers early evidence for a … Continue reading

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Early Indications Suggest Zika Virus Might Damage Adult Brains Resulting in Long-Term Neurological Conditions (NHS Choices / Cell Stem Cell)

Summary The Zika virus has been linked with microcephaly in human babies, and has also – more tentatively – been linked to Guillain-Barre Syndrome (GBS), but until now was not thought likely to affect the adult population beyond minor short-term … Continue reading

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