Genetics of the Obesity Risk Factor (BBC News / Nature)


Researchers in the international Genetic Investigation of Anthropometric Trait (Giant) consortium (and several other consortia listed below), have analysed the genetics behind body mass index (BMI) and identified 97 BMI-associated loci; i.e. gene regions which could explain why some people are more predisposed to gain weight.

Full Text Link


Fat map: largest genetic blueprint of obesity revealed. London: BBC Health News, February 11th 2015.

This relates to:

Full Text Link (Note: This article requires a suitable Athens password, a journal subscription or payment for access).


Locke, AE. Kahali, B. [and] Berndt, SI. [et al] (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature. February 12th 2015, 518, pp.197–206.

A list of authors, their contributions and affiliations, appears in the Supplementary Information.Other consortia involved:

  1. The LifeLines Cohort Study.
  2. The ADIPOGen Consortium.
  3. The AGEN-BMI Working Group.
  4. The CARDIOGRAMplusC4D Consortium.
  5. The CKDGen Consortium.
  6. The GLGC.
  7. The ICBP.
  8. The MAGIC Investigators.
  9. The MuTHER Consortium.
  10. The MIGen Consortium.
  11. The PAGE Consortium.
  12. The ReproGen Consortium.
  13. The GENIE Consortium.
  14. The International Endogene Consortium.

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