Tag Archives: β-amyloid Deposition

Biogen’s Aducanumab: Possibly the First Viable Drug Treatment of Alzheimer’s Disease? (BBC News)

Summary There were early hopes that the drug Aducanumab (from Biogen) might be able to slow down the build-up of amyloid protein in the brain, but trials were halted in March 2019 due to “disappointing” trial results. Subsequent re-analysis of … Continue reading

Posted in BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Person-Centred Care, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Early Signs of a Historic Breakthrough in the Treatment of Alzheimer’s Disease? (BBC News / Nature)

Summary Early results, based on small numbers of patients in a Phase I trial, indicate unprecedented progress in the development of a pharmacological treatment of Alzheimer’s Disease. The drug Aducanumab appears to combat (and reverse) the build-up of amyloid protein … Continue reading

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Models of Dementia Care, Pharmacological Treatments, Quick Insights, Scotland, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Dementia Risk From Cooked Meats? (BBC News / NHS Choices / PNAS)

Summary Research at the Icahn School of Medicine at Mount Sinai (New York), investigating the effect of Advanced Glycation End (AGEs) on mice and people, suggests that browning meat produces chemicals which may increase the risk of developing dementia. Mice … Continue reading

Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Issues in the Clinical Diagnosis of Dementia with Lewy Bodies (Translational Neurodegeneration)

Summary This article discusses recent progress, and problems remaining, in the clinical diagnosis of Dementia with Lewy Bodies (DLB). The sensitivity of accurate clinical diagnosis of DLB is said to be low. It seems likely that it may be possible … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment