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Tag Archives: β-Amyloid Plaques
Further Evidence on the Association Between Poor Oral Health and the Risk of Developing Alzheimer’s Disease. New Possibilities for Treatment? (BBC News / Science Advances)
Summary Analysis of brain tissue, spinal fluid, and saliva from persons with Alzheimer’s Disease indicates the presence of Porphyromonas gingivalis (the bacterium associated with chronic gum disease) in the brain and central nervous system. Animal research using mice indicates that … Continue reading
Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest
Tagged Alzheimer's Disease and Chronic Periodontitis, Alzheimer's Disease Causation and Possible Treatments, Alzheimer’s Disease, Amyloid Beta, Amyloid Beta Protein, Arginine-Gingipain A (RgpA), Arginine-Gingipain B (RgpB), Australia, Bazian, Behind the Headlines, Beta-Amyloid Plaques, Chronic Gum Disease, Chronic Periodontitis, Common Oral Problems and Risk Factors, COR271, COR388, Cortexyme, Dementia Risk Factors, Dental Healthcare, Dental Hygiene, Evidence for Risk Factors of Dementia, Gingipain, Gingipain Inhibitors, Gum Disease, Gum Disease (Periodontitis), Gum Disease Bacteria, Harvard University School of Dental Medicine, β-Amyloid Plaques, Jagiellonian University (Poland), Lysine-Gingipain (Kgp), Mice, Modifiable Risk Factors, Neuroprotective Agents, New Zealand, Oral Health in Older Adults, Oral Healthcare, Oral Hygiene, P. gingivalis, Periodontitis, Periodontitis and Risk of Developing Alzheimer’s Disease, Poland, Porphyromonas gingivalis, Porphyromonas Gingivalis in Alzheimer’s Disease, Risk Factors, Science Advances (Journal), Small-Molecule Gingipain Inhibitors: Possibly Neuroprotective, Tau Tangles, Transgenic Mice, University of Auckland, University of California, University of Louisville School of Dentistry, University of Melbourne
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Animal Study Explores the Potential of a Novel Diabetes Drug for Reducing Memory Loss in Dementia – In Mice (NHS Choices / Brain Research)
Summary Early animal research indicates that a new drug designed for the future treatment of diabetes may (one day) have an alternative re-use for reducing the memory-loss symptoms of Alzheimer’s Disease. Mice given a modified version of a so-called triple … Continue reading
Posted in Alzheimer's Society, Animal Studies, Charitable Bodies, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest
Tagged Alzheimer's Society, Alzheimer’s Disease and Diabetes, Amyloid Plaque Load, APP/PS1 Transgenic Mouse Model, Bazian, BDNF Levels in Hippocampus of APP/PS1 Mice, BDNF: Brain-Derived Neurotrophic Factor, Behind the Headlines, Biomedical and Life Science: Lancaster University, Brain Research, Brain Research (Journal), Brain-Derived Neurotrophic Factor (BDNF), China, Critical Appraisals, Department of Human Anatomy: Shaoyang University, Diabetes Drugs, Faculty of Health and Medicine: Lancaster University, GIP Receptor Agonists, GLP-1/GIP Dual Agonists, Glucagon-Like Peptide-1 (GLP-1) Analogs, Incretin Hormones, Incretin Mimetics, Inflammation, β-Amyloid Plaques, Key Laboratory of Cellular Physiology: Shanxi Medical University, Lancaster University, Medical College: Shaoyang University, Memory Loss, Ministry of Human Resources and Social Security (Shanxi Scholarship Council of China), Morris Water Maze Test, Mouse Model of Alzheimer’s Disease, Mouse Models of Alzheimer's Disease, Neuroprotection, Neuroprotection Research, Neuroprotective Agents, Neuroprotective Effects of Triple GLP-1/GIP/Glucagon Receptor Agonist, Novel GLP-1/GIP/Gcg Receptor Agonist, Off-Label Drug Repurposing Trials, Oxidative Stress, People's Republic of China, Potential Repurposing of Drugs to Slow Progression of Alzheimer’s Disease, Repurposing GLP-1 Agonists, Repurposing of Drugs, Second Hospital Neurology Department: Shanxi Medical University, Shanxi Medical University, Shanxi Medical University (China), Shanxi Scholarship Council of China, Shaoyang University, Shaoyang University (China), Synaptophysin (SYN) Levels, Transgenic Mice, Triple GLP-1/GIP/Glucagon Receptor Agonist, Triple GLP-1/GIP/Glucagon Receptor Agonists, Triple Receptor Agonist (TA) Drugs, Type 2 Diabetes, Type 2 Diabetes Drugs Development and Re-Purposing, Type 2 Diabetes Mellitus (T2DM), Water Maze Test
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