Tag Archives: 100000 Genomes Project

Chief Medical Officer’s Generation Genome Report (BBC News / Department of Health)

Posted on July 4, 2017 by Dementia and Elderly Care News

Summary The latest annual report from Professor Dame Sally Davies, the Chief Medical Officer (CMO) for England unveils a “genomic dream” vision, whereby whole genome screening (WGS) might soon become standard practice in the NHS, much like blood tests and biopsies. … Continue reading →

One More Genetic Link in the Longevity Enigma? (BBC News / Sanger Institute / Nature Communications)

Posted on May 29, 2017 by Dementia and Elderly Care News

Summary People living in the isolated Greek villages of Zoniana and Anogia have a noted tendency to live well into old age. They have a lower than expected incidence of cardiovascular disease, including heart problems, heart attacks and stroke. It … Continue reading →

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Stroke, Universal Interest | Tagged 100000 Genomes Project, 100000 Genomes Project Haplotypes, Anogia, Anogia Medical Centre (Greece), APOE, APOE Gene, Array Genotyping, BBC Health News, BMI: Body Mass Index, Body Fat, Body Mass Index (BMI), Cardiometabolic Associations, Cardiovascular Disease (CVD), Cardiovascular Fitness, Cardiovascular Risk, Cardiovascular System Disorders, CDKN2A/B, Cholesterol (HDL), CHRNA3/5, Churchill Hospital (Oxford), Cigarettes, Cretan-Isolated Populations, CVD: Cardiovascular Disease, Department of Nutrition and Dietetics: Harokopio University (Athens), Echinos Medical Centre (Xanthi: Greece), Educational Attainment, Epidemiology, Extra Year in Education Extends Lifespan by 11 months (DNA Study Assertion), FOXO3A, Genetic Correlations: Lifespan and Mortality, Genetic Profiling, Genetic Research, Genetic Variant rs145556679, Genetic Variants, Genetics, Genetics Versus Environment as Determinants of Longevity, Genetics Versus Lifestyle as Determinants of Longevity, Genome-Wide Association Meta-Analysis (GWAMA), Genome-Wide Association Studies, Genome-Wide Association Studies (GWAS), Greece, Greek Villagers, Harokopio University (Athens), HDL-Cholesterol, Heart Disease, HELIC (Hellenic Isolated Cohorts), HELIC MANOLIS Sequencing, High Density Lipoproteins (HDL), High-Density Lipoprotein (HDL) Cholesterol Levels, HLA-DQA1/DRB1, Human Longevity, Insulin Resistance, Isolated Greek Villages, Isolated Populations, Isolated Populations Research, Lifespan, Longevity, Low Density Lipoprotein Cholesterol (LDL-C), Low Density Lipoproteins (LDL), LPA, Lung Cancer, Medical School: University of Exeter, Mendelian Randomisation, METACARPA, Microarrays, Molecular Pathological Epidemiology, Mylopotamos (MANOLIS) and Pomak Villages Cohorts, Mylopotamos: Northern Crete, Nature Communications, Northern Crete, Obesity, Openness to New Experiences, Oxford Centre for Diabetes Endocrinology and Metabolism University of Oxford, Pomak Region of Northern Greece, Population Isolates, Radcliffe Department of Medicine: University of Oxford, Sanger Institute, Saturated Fats, School of Health Science and Education: Harokopio University (Athens), SH2B3, Smoking, Susceptibility to Coronary Artery Disease (CAD), Triglycerides, UK Biobank, Unexpected Genetic Heroes, University of Exeter, University of Exeter Medical School, University of Oxford, Usher Institute of Population Health Sciences and Informatics: University of Edinburgh, Very Low Density Lipoprotein cholesterol (VLDL), Wellbeing and Longevity, Wellcome Trust Centre for Human Genetics: University of Oxford, Wellcome Trust Sanger Institute, Wellcome Trust Sanger Institute: Human Genetics, WGS Haplotypes, Whole Genome Sequencing (WGS), Whole Genome Sequencing and Imputation, Zoniana | Leave a comment

Francis Crick Institute Opens for Genetic Research (MRC / BBC News)

Posted on September 2, 2016 by Dementia and Elderly Care News

Summary The new Francis Crick Institute has opened in London. “The Crick has been established through the collaboration of six funding partners: the MRC, Cancer Research UK, Wellcome, University College London, Imperial College London and King’s College London”. Full Text … Continue reading →

Posted in BBC News, Charitable Bodies, For Researchers (mostly), In the News, International, National, Quick Insights, UK, Universal Interest | Tagged 100000 Genomes Project, Biomedical Research, Cancer Research UK, Francis Crick Institute, Genetic Research, Genomics and Personalised Medicine, Imperial College London, King’s College London, London, Medical Research Council (MRC), Medical Research Council (UK), MRC: Medical Research Council, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Personalised Interventions, Personalised Medicine, Research and Development, Research and Innovation, Research Commitment, Sir Paul Nurse: Director of the Francis Crick Institute, UK Genomes Project: Genomics England, University College London, Wellcome Trust | Leave a comment

Developments in Dementia Research: From the Horses’ Mouths (NHS England / NIHR)

Posted on August 25, 2016 by Dementia and Elderly Care News

Summary Professor Alistair Burns (NHS England’s National Clinical Director for Dementia and Older Peoples’ Mental Health), and Professor Martin Rossor (NIHR National Director for Dementia Research), discuss current issues and new approaches in dementia research, touching briefly upon some of … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Models of Dementia Care, National, NHS England, NIHR, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged 100000 Genomes Project, A4 Study, Alistair Burns: Honorary Consultant Old Age Psychiatrist in the Manchester Mental Health and Social Care Trust (MMHSCT), Alistair Burns: NHS England’s National Clinical Director for Older People’s Mental Health, Alistair Burns: Professor of Old Age Psychiatry at University of Manchester, Alzheimer's Prevention Initiative, Alzheimer’s Disease Biomarkers, Alzheimer’s Prevention Initiative Study, Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study), APP and Presenilin, Asymptomatic Alzheimer’s Disease, Banner Alzheimer's Institute, Biomarkers, Chance Genetic Mutations, Colombia, Colombian Alzheimer's Prevention Initiative Registry in Medellín Antioquia, DIAN-TU Study, DIAN-TU Trial, Disease Modifying Treatment by 2025 (Aim), Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), Early Detection of Alzheimer’s Disease, Early Detection of Preclinical Disease, Genentech, Genomics, Genomics England, Genomics in the NHS, Genomics-Based Medicine, Global Outlook, Identification of People At Risk of Dementia, International Collaborations, International Programmes, International Research, Medellin (Colombia), Monoclonal Antibodies, MRC Neurochemical Pharmacology Unit, Mutational Signatures, National Clinical Director for Dementia, National Institute for Health Research (NIHR), National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, NIHR Clinical Research Network, NIHR Dementia Translational Research Collaboration, NIHR National Director for Dementia Research, NIHR Translational Research Collaboration, Overcoming Barriers, Participation in Research, Participation in Research Studies, Preclinical Alzheimer's Disease, Presenilin, Prodromal Alzheimer's Disease, Professor Alistair Burns, Professor Martin Rossor: Director of the NIHR Queen Square Dementia Biomedical Research Unit, Professor Martin Rossor: Former Director of the NIHR Dementia and Neurodegenerative Disease Research Network (DeNDRoN), Professor Martin Rossor: Former President of the Association of British Neurologists (2011-2013), Professor Martin Rossor: Honorary Consultant Neurologist at National Hospital for Neurology and Neurosurgery, Professor Martin Rossor: National Hospital (Queen Square), Professor Martin Rossor: NIHR National Director for Dementia Research, Professor Martin Rossor: UCL Institute of Neurology, Promisary Science, Reducing Downstream Effects of Disease, Research and Development, Research and Innovation, Research Commitment, Research Culture, Research Mapping, Research Networks, Research Promotion, Sharing Knowledge and Information, Slowing Progression of Disease (Stabilisation), Solanezumab (Sola or Solab), Solanezumab: Humanised Monoclonal Antibody, Therapeutic Nihilism (Avoiding), Translational Research, UK Genomes Project: Genomics England, University of Southern California’s Alzheimer’s Therapeutic Research Institute, Washington University School of Medicine | Leave a comment

Time to Deliver on the Five Year Forward View (BBC News / NHS England / Department of Health)

Posted on June 7, 2015 by Dementia and Elderly Care News

Summary The seven main national health bodies (namely NHS England, Monitor, the NHS Trust Development Authority (TDA), the Care Quality Commission (CQC), Public Health England, the National Institute for Health and Care Excellence (NICE) and Health Education England) jointly published … Continue reading →

Posted in Acute Hospitals, BBC News, Commissioning, Community Care, CQC: Care Quality Commission, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Health Education England (HEE), In the News, Integrated Care, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, NHS England, NICE Guidelines, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Public Health England, Quick Insights, Standards, UK, Universal Interest | Tagged 100000 Genomes Project, 5YFV: NHS Five Year Forward View, Accelerating Innovation, Access to Elective Care, Access to Mental Health Services, Ageing Population, Ageing Society, Agency Staff, Agency Staff (Exorbitant Waste of NHS Funding), Arm’s Length Bodies, Arm’s Length Bodies (Department of Health's ALBs), Atlas of Variations in Procurement, Bank And Agency Staff, Baroness Cumberlege, BBC Health News, Better Out-of-Hospital Care to Prevent Attendance and Admissions, Better Procurement, Cancer Treatment, Cancer Treatment Standards, Cancer Waiting Times, Center for Conservation Biology: Stanford University, Child and Adolescent Mental Health Services, Children and Young People IAPT Programme, Chronic Conditions, Clinical Networks, Coalition of the Willing, Commissioning and Funding, Commissioning for Value, Community and Voluntary Sector, Community Services, Community Volunteering, Constrained Funding, Contract and Agency Staff, Controls on VSM Pay, Coordinated Health and Social Care, Creative Use of NHS Estate, Culture, Culture and Leadership, Culture Change, Dalton Review (2014), Demand Management, Department of Biology and Woods Institute: Stanford University, Department of Psychology: Stanford University, Devon, Diabetes Prevention Programme, Efficiency Savings, Efficiency Savings: Diverting Resources to Front-Line Care, Emmett Interdisciplinary Program in Environment and Resources: Stanford University, Encouraging Innovation, Enforced Support (New Success Regime), Essex, Estate Efficiencies, Expert Patient Programme, Failing Hospitals, Failing Services (NHS and Social Care), Faustian Pact: Trading £8 Billion in Extra Funding For £22 Billion in Efficiency Savings, Finance and Procurement, Finance Directorate, Financial Context, Financial Pressures, Financial Sustainability in the NHS, Five Year Forward View, Five Year Forward View (NHS England), Forest Bathing, Former Health Secretary Jeremy Hunt, Forward View, Forward View Progress: Pilot Programmes Map, Funding Challenges, Gary Caplin: Chief Executive of Virginia Mason Hospital (Seattle), Global Economic Dynamics and the Biosphere: Royal Swedish Academy of Sciences, Governance Arrangements Driving the Five Year Forward View, GP Services Co-Located With A&E Department, GPs Co-Located With A&E Department, Greater Manchester, Greening Grey Britain Campaign, Harpal Kumar: Chief Executive of Cancer Research UK, Harpal Kumar: Head of NHS Cancer Taskforce, Health and Care Voluntary Sector Strategic Partner Programme, Health and Social Care, Health and Social Care Configuration, Health and Social Care Costs, Health and Social Care Integration, Health and Social Care Providers, Health and Social Care Reform, Health and Social Care Services, Health and Social Care: Integration Transformation Fund, Hospital Chains, Hospital Waiting Times, IAPT: Improving Access to Psychological Therapies, Improving Access to Mental Health Services by 2020, Improving Access to Psychological Therapies (IAPT), Integrated Out-of-Hospital Care, Integration of Health and Social Care, Integration of Health and Social Care for Older People, Integration Transformation Fund, Integration Transformation Fund (aka Better Care Fund), Integration Transformation Fund (ITF), International Recruitment, Jeremy Taylor (Chief Executive of National Voices), Laureate Institute for Brain Research (Tulsa), Lean and Quality Improvement, Lean and Six Sigma, Lean 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Committee, Staff Retention, Staff Sickness Levels, Stanford University, Stockholm Resilience Centre, Subgenual Prefrontal Cortex (sgPFC), Subgenual Prefrontal Cortex Activation, Success Regime (NHS England), Success Regimes in England, Surgical Never Events, Sustainable Funding, SWASFT Right Care Right Place Right Time Initiative, Sweden, Thinking Outside of the Box, Transformational Commissioning, UEC Vanguards, Upstream Interventions, Urbanization and Mental Illness, Urgent and Emergency Care Vanguards, Vanguard Programme, Variations in Procurement, Virginia Mason Hospital: Seattle, Voluntary and Community Sector, Waiting Time Standards, Waiting Time Targets in the NHS in England, Waiting Times and Access Standards, Workforce Advisory Board, Workforce Advisory Board Exemplars, Workforce Race Equality Standard | Leave a comment

NHS England Business Plan for 2015/16: Building the NHS of the Five Year Forward View (NHS England / BBC News / HSJ)

Posted on March 30, 2015 by Dementia and Elderly Care News

Summary NHS England’s business plan for 2015/16 expands upon the main goals and priorities for the year ahead. The plan involves ten priorities: Improving the quality of care and access to cancer treatment. Upgrading the quality of care and access … Continue reading →

Posted in Acute Hospitals, BBC News, Commissioning, Community Care, Diagnosis, End of Life Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Health Foundation, In the News, Integrated Care, Local Interest, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, NHS England, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Personalisation, Quick Insights, Standards, UK, Universal Interest | Tagged 100000 Genomes Project, 2015/16 NHS England Mandate Funding, 2015/16 NHS England Running Costs Budgets, 5YFV: NHS Five Year Forward View, Academic Health Science Networks (AHSNs), Accelerated Access Review, Access to Elective Care, Access to Mental Health Services, Active Workforce Campaign, Adult Social Care Services, Ageing and Dementia, Ageing Policy in the UK, Ageing Population, Ageing Society, BBC Health News, Be Clear on Cancer (BCOC), Cancer Recovery Package, Cancer Treatment, Cancer Treatment Standards, Child and Adolescent Mental Health Services, Children and Young People IAPT Programme, Chris Hopson: Chief Executive of NHS Providers, Clinical Excellence Awards, Clinical Models for Ambulance Services, Clinical Networks, Clinical Networks and Senates, Clinical Senates, Commissioning for Transformation, Commissioning Operations Directorate, Commissioning Strategy Directorate, Community Pharmacies, Community Pharmacy, Community Services and Primary Care, Crisis Care Concordat, Demand Management, Dementia Care: Unpaid Care Contribution, Democratic Society, Diffusion of Innovation, Digital Maturity, Efficient and Effective Care Programme, Elective Intensive Support Team, Emergency Preparedness Resilience and Response (EPRR), Encouraging Innovation, Finance Directorate, Financial Context, Financial Pressures, Financial Sustainability in the NHS, Five Year Forward View (NHS England), Former Health Secretary Jeremy Hunt, Forward View, Fraud Prevention and Management, Funding Gap (NHS), Future Commissioning Models, Future Focused Finance Transformation Programme, Genomic Medicine, Genomic Technologies, Genomics, Genomics in the NHS, Good Practice in Delivering Urgent and Emergency Care, Growth Priorities for Health and Social Care, Health Care Reform, Health Inequalities, Health Secretary Jeremy Hunt: 2015 Re-Appointment, Health Service Journal (HSJ), HSJ, Ian Dodge: NHS England's National Director of Commissioning Strategy, IAPT: Improving Access to Psychological Therapies, Improving Access to Mental Health Services by 2020, Improving Access to Psychological Therapies (IAPT), Improving Referral Pathways, Information Revolution, Innovation, Innovation and Improvement, Innovation in Bioinformatics, Innovation in Biotechnology, Innovation in Genetics, Innovative Access to Primary Care Services, Insight Strategy, Integrated Digital Care: An Information Revolution, Integrated Personalised Commissioning (IPC), Integrated Personalised Commissioning Demonstrator Sites, Integration of Health and Social Care, Investing for Transformation, Involve, Local Health Economies, Mental Health Crisis Care Concordat, Mental Health Funding, National Information Board (NIB), National Innovation Accelerator Sites, New Care Models, New Care Models: Vanguard Sites, NHS Belongs to the People, NHS Citizen, NHS Citizen Model, NHS Citizen Programme, NHS Continuing Healthcare, NHS Diabetes Prevention Programme, NHS England (Formerly the NHS Commissioning Board), NHS England Business Plan for 2015/16, NHS England Five Year Forward View, NHS England Mandate Funding, NHS England Public Voice, NHS England Running Costs Budgets, NHS England's Realising the Value Programme, NHS England’s Five Year Forward View, NHS Five Year Forward View, NHS Five Year Forward View (5YFV), NHS Genomic Medicine Centres, NHS Improving Quality, NHS Leadership Academy, NHS Mental Health Services, NHS Reform, NHS Service Reconfiguration, NHS 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Innovation, Review of Improvement and Leadership Capability, Rt Hon Jeremy Hunt MP: Former Secretary of State for Health, Safer Faster Better: Good Practice in Delivering Urgent and Emergency Care, Science and Innovation, Self Management of Chronic Disease, Self-Care, Self-Help, Senates, Service Redesign, Service Redesign (Telehealth), Service Transformation, Shared Decision-Making, Shared Strategic Planning, Simon Stevens: Chief Executive of NHS England, Small Business Research Initiative, Standards, Stephen Dalton: Mental Health Network, Strategic Planning, Strategic Planning and Commissioning, Summary Care Record (SCR), Support for People with Complex Needs, Support for Self Management, Supporting Carers, Supporting Research and Innovation, Supporting Self-Care, Tackling Barriers to Innovation, Tavistock Institute, Technology and Innovation, Thinking Like a Patient and Acting Like a Taxpayer, Transformation and Corporate Operations, Transformational Commissioning, Transformational Technologies, Transformative Technology, Transforming Care Programme, Transforming Community Services (TCS), Transforming Urgent and Emergency Care Services, Transparency, Transparency and Accountability, UK Genomes Project: Genomics England, Urgent and Emergency Care Networks, Urgent and Emergency Care Services, Urgent and Emergency Care Services in England, Whole System Change, Whole System Transformation, Widening Digital Participation Programme, Workforce Race Equality Standard, Workforce Race Equality Standard Data and Dashboard | Leave a comment

Eleven Genomics Medicine Centres Planned for England (BBC News / Department of Health / NHS England)

Posted on December 22, 2014 by Dementia and Elderly Care News

Summary The NHS has announced further steps in a genetics project, which will involve 11 Genomics Medicine Centres being created in English hospitals to gather DNA information. The aim is to support the 100,000 Genomes Project in research towards the … Continue reading →

Tag Archives: 100000 Genomes Project

One More Genetic Link in the Longevity Enigma? (BBC News / Sanger Institute / Nature Communications)

Francis Crick Institute Opens for Genetic Research (MRC / BBC News)

Eleven Genomics Medicine Centres Planned for England (BBC News / Department of Health / NHS England)

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