Tag Archives: Abnormal Proteins (Prions)

Possible Future Treatment of CJD? (BBC News)

Summary University College London Hospitals NHS Foundation Trust (UCLH)’s National Prion Clinic has been granted the go-ahead to test the use of a man-made antibody treatment (PRN100), with a view to halting or slowing the progression of sporadic CJD. “We … Continue reading

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Structure of Tau Filaments in Alzheimer’s Disease Discovered (MRC / BBC News / Nature / NHS Choices)

Summary Research at the MRC Laboratory of Molecular Biology has taken advantage of a “resolution revolution” in microscopy to uncover the atomic structure of Tau filaments (one of the two types of the abnormal tangles associated with Alzheimer’s Disease). “Tau forms … Continue reading

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Urine Test for Creutzfeldt-Jakob Disease (CJD)? (BBC News / MRC / JAMA Neurology / NEJM)

Summary It may one day be possible to use a non-invasive diagnostic urine test to discover whether or not patients have sporadic Creutzfeldt-Jakob Disease (sCJD). Full Text Link Reference A urine test for Creutzfeldt-Jakob Disease may be possible. London: Medical … Continue reading

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Exploring Disease-Modifying Treatments for Lewy-Body Dementia (Frontiers in Neuroscience)

Summary The authors of this review remind readers that there are currently no disease-modifying therapies for Dementia with Lewy bodies (DLB). DLB accounts for perhaps 25% of all dementia cases. This review covers therapeutic directions which have been explored for … Continue reading

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Minimising CJD and vCJD Transmission Risks in Healthcare and Community Settings (Department of Health)

Summary The Advisory Committee on Dangerous Pathogens’ Transmissible Spongiform Encephalopathy (ACDP TSE) Risk Management Subgroup has released updated guidance which aims to minimise the risks of transmission of CJD and vCJD in healthcare and other public settings. Full Text Link … Continue reading

Posted in Acute Hospitals, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Guidelines, Local Interest, Management of Condition, National, NHS, Person-Centred Care, Practical Advice, Quick Insights, Standards, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Evolutionary Mutation of Human Prion Protein May Prevent Prion Diseases? (NHS Choices / BBC News / Nature)

Summary A natural human mutation (called V127) in the gene encoding prion protein may offer resistance to CJD. A study using mice with this genetic mutation appears to confirm resistance to prion diseases. This finding may in future help in … Continue reading

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Lancet Seminar on Parkinson’s Disease (Lancet / Advances in Integrative Medicine / Translational Proteomics / Parkinson’s UK / BBC News)

Summary Coinciding with Parkinson’s Awareness Week 2015 (April 20th – 26th 2015), the following Lancet review / seminar covers the clinical features, risk factors, pathology, genetics, pathogenesis, diagnosis and treatment of Parkinson’s Disease. Full Text Link (Note: This article requires … Continue reading

Posted in Acute Hospitals, BBC News, Charitable Bodies, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Non-Pharmacological Treatments, Parkinson's Disease, Pharmacological Treatments, Quick Insights, Scotland, Systematic Reviews, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment