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Tag Archives: Age-Related Neurodegenerative and Neurovascular Diseases
More on Diabetes in Later Life as a Dementia Risk Factor (Diabetes Care)
Summary Further epidemiological evidence indicates that diabetes onset in late life is a risk factor for dementia. A cohort study involving 169,114 new cases of dementia in Ontario (Canada) found that dementia risk was 16% higher among the subgroup with … Continue reading →
Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Quick Insights, Statistics, Universal Interest
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Tagged Age-Related Neurodegenerative and Neurovascular Diseases, American Diabetes Association (ADA), Canada, Canada Department of Medicine: Queen's University, Cardiovascular Risk Factors, Cerebral Vascular Disease, Cerebrovascular Disease, Dementia Risk Factors, Department of Medicine: University of Toronto, Diabetes, Diabetes and Multiple Morbidities, Diabetes Care, Epidemiology, Epidemiology and Statistics, Evidence for Risk Factors of Dementia, Hypoglycaemia, Institute for Clinical Evaluative Sciences (ICES), Modifiable Risk Factors, Ontario (Canada), Overlapping Risk Factors, Peripheral Vascular Disease, Queen's University (Kingston Canada), Risk Factors, Toronto, University of Toronto, University of Toronto: Canada Institute for Clinical Evaluative Sciences (ICES)
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Frontotemporal Dementia: Basic Disease Processes Uncovered? (Alzheimer’s Society / Journal of Cell Biology)
Summary Researchers studying the connections between neurons in fruit flies may have identified mechanisms which are involved neurodegeneration in Frontotemporal Dementia (FTD). FTD affects the frontal and temporal lobes (in human brains). A protein called CHMP2B can cause neuronal connections … Continue reading →
Posted in Alzheimer's Society, Animal Studies, Charitable Bodies, For Doctors (mostly), For Researchers (mostly), International, Quick Insights, UK, Universal Interest
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Tagged Activator Protein-1), Age-Related Neurodegenerative and Neurovascular Diseases, c-Jun N-terminal kinase (JNK), CHMP2B, Disease Modifying Treatment by 2025 (Aim), Drosophila melanogaster, Endosomal JNK-Scaffold POSH (Plenty-of-SH3s), ESCRT-III Dysfunction, Frontotemporal Dementia, Frontotemporal Dementia (FTD), Fruit Flies, Fruit Fly Model of Frontotemporal Dementia, JCB: Journal of Cell Biology, Journal of Cell Biology, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurology, Novel Targets in Neurodegeneration, Pick’s Disease (Frontotemporal Dementia), POSH (Plenty-of-SH3s), Potential Drug Targets, RAB8 Deficiency, Rab8 POSH and TAK1 (Regulation of Synaptic Growth), RAB8 Protein, Synaptic Overgrowth and Endosomal Dysfunction, Transgenic Drosophila
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Dementias Platform UK (Department of Health / Dementia Challenge / World Dementia Council / MRC)
Summary A new multimillion-pound platform for dementia research, entitled the “Dementias Platform UK (DPUK)”, has been launched by the Medical Research Council. The aim is to ensure the UK is one of the best places in the world to research dementia. … Continue reading →
Posted in Charitable Bodies, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Parkinson's Disease, Pharmacological Treatments, Quick Insights, Standards, UK, Universal Interest
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Tagged Academia-Industry Partnerships, Age-Related Neurodegenerative and Neurovascular Diseases, Alzheimer's Disease and Dementia, Araclon, Challenge on Dementia (David Cameron), Charitable Funding, Clinical Research Infrastructure Award, Collaborative Projects, Cross-Sector Partnerships, Data Sharing, Dementia and Neurodegenerative Diseases Research Network, Dementia Challenge, Dementia Innovation, Dementia Risk Factors, Dementias Platform UK, Dementias Platform UK (DPUK), Dementias Research Platform UK (DPUK), Dennis Gillings: Former World Dementia Envoy, Department of Health Dementia Challenge, DPUK: Dementias Platform UK, Dr John Gallacher: University of Cardiff, George Freeman: Former Life Sciences Minister, Global Action Against Dementia, Global Envoy for Dementia Innovation, Global Leadership, Global Outlook, Global Social Investment for Dementia, GSK, Incentives and Investment, Incentives for Drug Development, Integrated Development Pathway, International Collaborations, International Dementia Research Inventories, International Programmes, IXICO, Janssen Research & Development, Johnson & Johnson Innovation, Medical Research Council (MRC), MedImmune (AstraZeneca), Motor Neurone Disease, MRC Dementias Research Platform UK (DPUK), MRC: Medical Research Council, Neurodegeneration, Neurodegenerative Disease Research, NIHR Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), NIHR-MRC Dementia Deep and Frequent Phenotyping, Partnership Working, Prime Minister's Challenge on Dementia, Prime Minister’s Dementia Challenge, Research and Innovation, Resource and Incentives, SomaLogic, WDC: World Dementia Council, World Dementia Council
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Google’s “Moonshot Project” on Tackling Ageing (Financial Times / Reuters / BBC News / ICO / Health and Technology / HTN)
Summary Arthur Levinson, formerly of Genentech, has left Roche to avoid any potential conflict of interest in his role as chief executive of Google’s Calico start-up company. Calico recently agreed a $1.5bn alliance with AbbVie, a rival of Roche, to develop treatments for … Continue reading →
Posted in Assistive Technology, In the News, International, Management of Condition, Non-Pharmacological Treatments, Parkinson's Disease, Pharmacological Treatments, Quick Insights, Universal Interest
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Tagged 23andMe, AbbVie, Acute Kidney Injury (AKI), Age and Ageing, Age-Related Disease Research, Age-Related Neurodegenerative and Neurovascular Diseases, Ageing and Dementia, Ageing and Society, Ageing Population, Ageing Well, AI for Good Programme (Microsoft), AI for Health Programme (Microsoft), Arthur Levinson, Artificial Intelligence, Artificial Intelligence (AI), Attitudes to Ageing, Basline Study: Collection of Anonymous Genetic and Molecular Information, BBC Health News, Big Data, Big Pharma, BRAC, Compensation for Shaky Hands (Assistive Technology), Data Protection Act (1998), Data Protection Procurement Rules and Competition Rules (Potential Barriers to Information Sharing), Data Protection Procurement Rules and Competition Rules (Potential Barriers to Partnership Working), Data Sharing, Data Sharing Agreement, Data Sharing for Better Health, DeepMind Health, Diffusion of Innovation, Disease-Detecting Nanoparticles, Economist (Journal), Elizabeth Denham, Elizabeth Denham: Information Commissioner, Encouraging Innovation, Essential Tremor, Faculty of Law and Computer Laboratory: University of Cambridge, Financial Times, Fred Hutchinson Cancer Research Center (Seattle), FT.com, Genentech, Google, Google Ageing-Related Ambitions, Google Basline Study: Anonymous Genetic and Molecular Information, Google Health-Related Ambitions, Google Moonshot Projects, Google Moonshot Projects: Ageing-Related, Google X, Google X: Cutting-Edge Technology Projects, Google X: Potentially Revolutionary Innovation, Google's DeepMind, Google's Research Division: Google X, Google's Social Network: Google+, Google’s Calico, Google’s DeepMind and Royal Free Trust Data-Sharing Agreement, Google’s Health Portfolio, Health and Technology (Journal), Health Technology, Healthy Life Expectancy, HTN: Health Tech Newspaper, Human Longevity, Information Commissioner’s Office (ICO), Information Commissioner’s Website, Intelligent Retinal Imaging Systems (IRIS), International Collaborations, International Dementia Research Inventories, International Programmes, International Research, Lift Labs, Longevity, Novartis Foundation, Open Access Databases, Open Access Knowledge Resources, Open Access Research, Open Data and Big Data, Open Science, Open Source Solutions, Partnership and Collaboration, Partnership Working, PATH, Pharmaceutical Industry, Pharmacological Research, Policies on Ageing, Preventative Care, Proactive Care, Reinventing Ageing, Research and Innovation, Reuters, Roche, Royal Free Hospital (London), Royal Free London NHS Trust, Royal Free NHS Foundation Trust, Science of Ageing, Seattle Children’s Research Institute, Smart Contact Lenses, Stabilization Technology: Tremor Cancellation, Streams app (Google’s DeepMind), Supporting Healthy Lifestyles, Tremor, Tremor and Other Hyperkinetic Movements, Tremor Cancellation Spoon (Stabilization Technology), Tremor-Cancelling Devices
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Exposure of Aged Mice to Young Blood Plasma Improves Age-Related Cognitive Impairment? (BBC News / NHS Choices / Nature Medicine / Science)
Summary Researchers at Stanford University believe they might have discovered a novel method of slowing, or even reversing, a range of ageing processes (mental and physical). Their work, based on mice so far, involved injecting the blood of young mice … Continue reading →
Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest
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Tagged AfaSci Research Laboratory: California, Age and Ageing, Age-Related Cognitive Impairment, Age-Related Neurodegenerative and Neurovascular Diseases, Aged Mice: Exposure to Young Blood Plasma, Ageing, BBC Health News, Behind the Headlines, Blood Plasma, Blood Transfusions, Brigham and Women's Hospital: Boston, Cardiovascular Division: Brigham and Women's Hospital, Cellular Ageing, Center for Systems Biology and Department of Radiology: Massachusetts General Hospital, Center for Tissue Regeneration Repair and Restoration: VA Palo Alto Health Care System, Cognitive Decline, Cognitive Decline Studies, Cognitive Impairment, Contextual Fear Conditioning, Critical Appraisals, Department of Anatomy: University of California San Francisco, Department of Neurology and Neurological Sciences: Stanford University School of Medicine, Department of Stem Cell and Regenerative Biology: Harvard University, Developmental and Stem Cell Biology Graduate Program: University of California San Francisco, Disease-Modifying Therapies for Dementia, Dr Tony Wyss-Coray: Stanford University School of Medicine, Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research: San Francisco, GDF11, Harvard Medical School, Harvard Stem Cell Institute, Harvard University, Hippocampus, Hippocampus-Based Cognitive Processes, Hippocampus-Dependent Memory Deficits, Howard Hughes Medical Institute, Joslin Diabetes Center and the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Late-Life Cognitive Decline, Massachusetts General Hospital, Mice, Nature Medicine, Neurodegeneration, Neurodegenerative Disease Research, Neurogenesis, Neurogenic Rejuvenation of the Aging Mouse Brain (Blood Plasma), Neuroscience Graduate Program: Stanford University School of Medicine, Rejuvenation of Synaptic Plasticity, Rejuvenation of the Aging Mouse Brain (Blood Plasma), Spatial Learning and Memory, Stanford University School of Medicine, Stanford [California], Synaptic Plasticity, Translational Research, United States, University of California San Francisco, USA, VA Palo Alto Health Care System, Vascular and Neurogenic Rejuvenation, Vascular Rejuvenation of the Aging Mouse Brain (Blood Plasma), Young Blood (Rejuvenating Effects)
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