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Tag Archives: Alzheimer’s Disease: Diagnosis
Blood Test Able to Predict Alzheimer’s Disease Decades Before Symptoms? (BBC News / Neurology)
Summary Research published in the Neurology journal claims a significant breakthrough in the development of a blood test (for plasma Aβ42/Aβ40) which may be able to predict Alzheimer’s Disease onset with 94% accuracy. Due caution: “But it’s important to note … Continue reading
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest
Tagged Alzheimer's Disease: Diagnosis, Alzheimer’s Early Screening, Amyloid, Amyloid and Tau PET, Amyloid Beta, Amyloid Beta (Aβ42 and Aβ40), Amyloid Beta Protein, Amyloid-β (Aβ), Amyloid-β Protein, BBC Health News, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood Test for Brain Amyloidosis: Validated Using Amyloid PET and CSF p-tau181/Aβ42 as Reference Standards, Blood Tests, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Imaging, Brain Research, Case Finding, Conversion to Dementia From Prodromal Disease, Dementia Diagnosis, Dementia Innovation, Dementia Research, Dementia Screening, Department of Neurology: Washington University, Diagnosis, Diagnosis of Alzheimer's Disease, Diagnostic Imaging, Division of Biostatistics: Washington University, Drug Development for Alzheimer's Disease, Early Detection of Preclinical Disease, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Hope Center for Neurological Disorders: Washington University, Knight Alzheimer's Disease Research Center: Washington University, Mallinckrodt Institute of Radiology: Washington University, Neurology (Journal), Non-Invasive Biomarkers, Plasma Biomarkers, Plasma β-Amyloid 42/40, Plasma Protein Markers of MRI Measures in Asymptomatic Individuals, Preclinical Alzheimer's Disease, Preclinical Biomarkers in Alzheimer's Disease, Predictive Ability (of Tests), Prodromal Alzheimer's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, Rapid Screening, Recruitment Onto Dementia Clinical Trials, SAP (Protein), SAP: Serum Amyloid Protein, Screening, Screening for Dementia, Washington University School of Medicine
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Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)
Summary Further discussion about the possibilities of using inexpensive eye tests to detect Alzheimer’s Disease, perhaps years before symptoms appear. This particular technique involves the examination of blood vessels and blood flow in the retina, as detected by Octa (Optical … Continue reading
Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest
Tagged Alzheimer's Disease: Diagnosis, Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease Biomarkers, Assessment and Diagnosis, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Central Subfield Thickness (CST), Cognitive Impairment, Critical Appraisals, Dementia Case Finding, Dementia Diagnosis, Dementia Screening, Diagnosis, Diagnosis of Alzheimer's Disease, Diagnostics, Duke University in North Carolina, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Treatment Diabetic Retinopathy Study, Eye Examinations, Foveal Avascular Zone (FAZ) Area, Karen L. Wrenn Alzheimer's Disease Award, Macular Ganglion Cell-Inner Plexiform Layer (GC-IPL), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment, National Institutes of Health, National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Digital (Formerly NHS Choices), Non-Invasive Biomarkers, Octa: Optical Coherence Tomography Angiography, Ophthalmology Retina, Optical Coherence Tomography, Optical Coherence Tomography Angiography (OCTA), Preclinical Alzheimer's Disease, Rapid Screening, Research to Prevent Blindness Inc. (New York), Retina as Early Biomarker of Neurodegeneration, Retinal Biomarkers, Retinal Examination in Neurodegenerative Diseases, Retinal Microvascular and Neurodegenerative Changes in Alzheimer’s Disease, Retinal Microvascular and Neurodegenerative Changes in Mild Cognitive Impairment, Retinal Vessel Density (VD), Screening, Screening for Dementia, Timely Diagnosis, US National Institutes of Health (NIH), USA
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Limited Usefulness of MRI for Improving the Prediction of Dementia? (BMJ)
Summary Research indicates that MRI does not significantly improve the prediction of dementia. It does have some value in differential diagnosis. Full Text Link Reference Stephan, BC. Tzourio, C. [and] Auriacombe, S. [et al] (2015). Usefulness of data from magnetic … Continue reading
Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Quick Insights, UK
Tagged Alzheimer's Disease: Diagnosis, Assessment and Diagnosis, BMJ, Bordeaux University Hospital, Brain Imaging, Brain Volume, British Medical Journal (BMJ), Cerebral Brain Volume, Dementia Diagnosis, Dementia Screening, Diagnosis of Dementia, Differential Diagnosis, Dijon Magnetic Resonance Imaging Study Cohort, Early Diagnosis, Early Screening, France, France University of Bordeaux, French Three-City Study, Grey-Matter Volume, Hippocampal Volume, Imaging, Inserm Research Centre for Epidemiology and Biostatistics (U897), Inserm: Team Epidemiology and Neuropsychology of Brain Aging, Inserm: Team Neuroepidemiology, Institute of Health and Society: Newcastle University, MRI Brain Imaging, Neuroimaging, Neuroimaging in Dementia Diagnosis, Neuroimaging of Dementia, Neuroimaging Tools, Newcastle University, Screening for Dementia, Team Neuroepidemiology (Inserm), Three-City Study, Timely Diagnosis, White Matter Lesion (WML)
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Skin Cells: A New Non-Invasive Biomarker? (BBC News / American Academy of Neurology)
Summary Skin may be a good candidate biomarker for detecting hidden brain disorders earlier. Abnormal proteins which accumulate in the brain in neurodegenerative disorders such as Alzheimer’s Disease and Parkinson’s Disease can be found in the skin too. Research is … Continue reading
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Parkinson's Disease, Quick Insights, Universal Interest
Tagged Abnormal Proteins, Abnormal Proteins (Alpha-Synuclein), Abnormal Proteins (Tau), Alzheimer's Disease: Diagnosis, American Academy of Neurology, American Academy of Neurology’s 67th Annual Meeting (Washington 2015), Assessment and Diagnosis, BBC Health News, Biomarkers, Central Hospital at the University of San Luis Potosi, Dementia Diagnosis, Diagnostic Markers, Diagnostic Testing, Differential Diagnosis, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Differential Diagnosis, α-Synuclein, α-Synuclein Aggregation, Mexico, National Council of Science and Technology of Mexico, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Non-Invasive Biomarkers, Parkinson’s Disease Diagnosis, Parkinsonism, Post-Mortem Studies, Skin Biopsies, Skin Cells, Skin Tests, Synucleinopathy, Tau, Tau Pathology, Tau Protein, Timely Diagnosis, University of San Luis Potosi (Mexico)
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Dementia Diagnosis and Prediction Using Eye Examinations? (BBC News)
Summary A £1.1m three year study involving researchers from Dundee University and Edinburgh will investigate whether eye tests can aid non-invasive diagnosis by providing an “early warning” of Alzheimer’s Disease and other conditions. It is thought that changes in the eye … Continue reading
Posted in BBC News, Diagnosis, For Researchers (mostly), In the News, Quick Insights, Scotland, UK, Universal Interest
Tagged Alzheimer's Disease: Diagnosis, Assessment and Diagnosis, BBC Health News, BBC Tayside and Central Scotland, Dementia Diagnosis, Diagnostic Markers, Diagnostic Testing, Differential Diagnosis, Drusen (Spots on Retina), Dundee, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Edinburgh, Engineering and Physical Sciences Research Council (EPSRC), EPSRC: Engineering and Physical Sciences Research Council, Eye Cells, Eye Examinations, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuronal Loss, Ninewells Hospital, Non-Invasive Biomarkers, Optomap Screening Test, Optos (Retinal Imaging Company), Retinal Ganglion Cell Layer, Retinal Inner Nuclear Layer, Retinal Neuronal Loss, Timely Diagnosis, University of Dundee
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