Tag Archives: Alzheimer’s Disease

Deep Brain Stimulation for Improving Symptoms in Alzheimer’s Disease (BBC News)

Summary A brief BBC News item explores the potential of deep brain stimulation (DBS) therapy for improving wellbeing and cognitive function in patients with Alzheimer’s Disease and other forms of dementia. “Although we are not talking about treating the Alzheimer’s … Continue reading

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)

Summary An experimental drug for the treatment of Huntington’s Disease shows early signs of being able to lower the level of misfolded proteins (safely) in the brains of patients, thereby having the potential to slow or halt the progression of … Continue reading

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Grounds for Cautious Optimism Regarding Two Drugs Re-Purposed for Neurodegenerative Diseases? (BBC News / MRC / NHS Choices / Brain)

Summary Animal research, involving mice, has indicated promising results for the potential of two re-purposed drugs in helping to slow or halt the progression of a number of neurodegenerative brain diseases, including dementia. “The best known drug of the pair … Continue reading

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Fourth Annual Deep Brain Stimulation (DBS) Think Tank (Frontiers in Integrative Neuroscience / International Journal of Neuroscience)

Summary An annual round-up of developments in the field of Deep Brain Stimulation (DBS). (x3). Full Text Link Reference Deeb, W. Giordano, JJ. [and] Rossi, PJ. [et al] (2016). Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: a … Continue reading

Posted in Depression, For Doctors (mostly), For Researchers (mostly), International, Mental Health, Non-Pharmacological Treatments, Parkinson's Disease, Quick Insights | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Exploring the Relationship Between Worsening Depression and Increased Dementia Risk (BBC News / Lancet Psychiatry / JGCR)

Summary Researchers in the Netherlands, following 3325 adults aged over 55 years for 11 years, have discovered an association between symptoms of depression which increase steadily over time in older adults and a greater likelihood of developing early signs of … Continue reading

Posted in BBC News, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Quick Insights, Statistics, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Severe, Persistent and Fatal Delirium (Dementia and Geriatric Cognitive Disorders Extra)

Summary Delirium is typically a transient syndrome, but this study concentrates on severe persistent and potentially fatal delirium. Just 15 cases are considered, involving diverse diagnoses including Alzheimer’s Disease, dementia with Lewy bodies, Creutzfeldt-Jakob disease and progressive supranuclear palsy. Full … Continue reading

Posted in Acute Hospitals, Delirium, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Quick Insights | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Novel Approach to Prevention of Alzheimer’s Disease Explored in Laboratory (Express / PloS One)

Summary Researchers at the University of California, San Diego, have explored a different approach to mainstream research into the prevention of Alzheimer’s Disease. It is believed that Alzheimer’s Disease develops when amyloid precursor protein (APP) gets cut-up by enzymes and … Continue reading

Posted in Animal Studies, For Doctors (mostly), For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Drug Alteration to Brain’s Immune System Prevents Mice Developing Alzheimer’s Dementia? (BBC News / Journal of Neuroscience)

Summary Latest research evidence, from Duke University in the US, suggests that the immune system plays a part in the development of Alzheimer’s Disease (in mice). It appears that immune cells which attack nutrients in the brain may be an … Continue reading

Posted in Animal Studies, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Alzheimer’s Disease: Persistent Perplexity (BMJ)

Summary A recent British Medical Journal article examines what is known, and remains uncertain, about the pathogenesis of Alzheimer’s Disease. It also touches on the difficulty of diagnosis, and current prospects for disease-modifying treatments. Full Text Link (Note: This article … Continue reading

Posted in Acute Hospitals, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, UK | Tagged , , , , | Leave a comment

Pharmacological Treatments for Alzheimer’s Disease in Primary Care / Management of Cognitive Symptoms (DTB / Nursing Times)

Summary A Drug and Therapeutics Bulletin (DTB) article reviews the evidence concerning drugs prescribed for cognitive symptoms in Alzheimer’s Disease and discusses some issues in their prescription. Donepezil, galantamine and rivastigmine are licensed for mild to moderate Alzheimer’s Disease in … Continue reading

Posted in Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Management of Condition, Models of Dementia Care, NICE Guidelines, Pharmacological Treatments, Practical Advice, Quick Insights, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment