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- The Diversionary Value of Music Playlists for Patients With Dementia in Accident and Emergency Settings (Nurses.co.uk / BBC News)
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Tag Archives: Alzheimer’s Disease
Deep Brain Stimulation for Improving Symptoms in Alzheimer’s Disease (BBC News)
Summary A brief BBC News item explores the potential of deep brain stimulation (DBS) therapy for improving wellbeing and cognitive function in patients with Alzheimer’s Disease and other forms of dementia. “Although we are not talking about treating the Alzheimer’s … Continue reading
Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Quick Insights, Universal Interest
Tagged Alzheimer's Disease, Andres Lozano (Neurosurgeon), Brain Imaging, Canada, Deep Brain Stimulation, Deep Brain Stimulation (DBS), Deep Brain Stimulation for the Treatment of Alzheimer Disease, Deep Brain Stimulation for the Treatment of Dementia, Deep Brain Stimulation of Nucleus Basalis of Meynert (NBM DBS), Dr Carol Routledge: Alzheimer's Research UK, LaVonne Moore, Neurodegeneration, Neurodegenerative Diseases, Neurological Disease, Nucleus Basalis of Meynert, Nucleus Basalis of Meynert (NBM), Ohio State University Wexner Medical Center, Parkinson’s Dementia, Parkinson’s Disease Dementia, Treatment of Alzheimer's Disease, United States, USA, Wexner Medical Center: Ohio State University
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The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)
Summary An experimental drug for the treatment of Huntington’s Disease shows early signs of being able to lower the level of misfolded proteins (safely) in the brains of patients, thereby having the potential to slow or halt the progression of … Continue reading
Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, UK, Universal Interest
Tagged Alzheimer's Disease, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Antisense Oligonucleotides (ASO), Biomedical Research Centres (NIHR), Canada, Clinical Trial NCT02519036, Gene Silencing to Suppress Transcription and Translation of Huntingtin, Gene-Silencing, Genetic Research, Genetics, Germany, Huntingtin Protein, Huntingtin Protein (HTT), Huntington Disease, Huntington's Disease (HD): an Autosomal-Dominant Inherited Neurodegenerative Disorder, Huntington's Disease Centre: UCL Institute of Neurology, Huntington’s Disease, Ionis Pharmaceuticals, IONIS-HTTRx: Huntingtin-Lowering Drug, α-Synuclein, α-Synuclein Aggregation, Leonard Wolfson Experimental Neurology Centre (LWENC), Leonard Wolfson Experimental Neurology Centre: University College London, Misfolded Proteins, Mutant HTT (mHTT) Protein, Mutant Huntingtin (mHTT), National Institute for Health Research (NIHR), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuronal Loss, Neuroprotection, Prof. Giovanna Mallucci, Professor Sarah Tabrizi: IONIS-HTTRx Global Chief Investigator, Professor Sarah Tabrizi: UCL Institute of Neurology, Protein Misfolding, Roche, Synucleinopathy, Tau, Tau Protein, Tauopathy, University College London (UCL), University College London Hospitals Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, University College London Hospitals NHS Foundation Trust / University College London (NIHR) Biomedical Research Centre
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Exploring the Relationship Between Worsening Depression and Increased Dementia Risk (BBC News / Lancet Psychiatry / JGCR)
Summary Researchers in the Netherlands, following 3325 adults aged over 55 years for 11 years, have discovered an association between symptoms of depression which increase steadily over time in older adults and a greater likelihood of developing early signs of … Continue reading
Posted in BBC News, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Quick Insights, Statistics, Universal Interest
Tagged Alzheimer's Disease, Association Between Worsening Depression and Increased Dementia Risk, Australia, BBC Health News, Center for Epidemiology Depression Scale (CES-D), Conversion to Dementia From Prodromal Disease, Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction and Prevention, Department of Developmental Disability and Centre for Healthy Brain Ageing: University of New South Wales, Department of Epidemiology: Erasmus Medical Center, Department of Neurology: Erasmus Medical Center, Department of Psychiatry: Erasmus Medical Center, Department of Psychiatry: King George’s Medical University (India), Department of Radiology: Erasmus Medical Center, Depression and Dementia, Depression in Adults, Depression in Dementia: Risk Factors, Depression in Older People, Depressive Symptoms, Depressive Symptoms (Five Trajectories), Disease Predictors, Early Dementia, Epidemiology, Epidemiology and Statistics, Erasmus Medical Center (Rotterdam), Erasmus University Medical Center, Etiopathogenesis Model of Depression in Dementia, Faculty of Medicine: University of New South Wales, Five Trajectories of Depressive Symptoms, Hospital Anxiety and Depression Scale-Depression, Hypothetical Prodromes of Dementia, Increasing Depressive Symptoms, Increasing Depressive Symptoms Associated with a Higher Risk of Dementia, Increasing Depressive Symptoms: Statistical Prodrome of Dementia, India, Journal of Geriatric Care and Research (JGCR), King George’s Medical University (India), Lancet Psychiatry, Latent Class Trajectory Modelling, Netherlands, Netherlands Ministry for Health Welfare and Sports, Netherlands Ministry of Education Culture and Science, Overlapping Risk Factors, Patterns of Depression, Prodromal Alzheimer's Disease, Risk Factors, Risk Factors of Depression and Dementia in Elderly, Risk Prediction and Stratification, Rotterdam (Netherlands), School of Psychiatry: University of New South Wales, Trajectories of Depression, Trajectories of Depressive Symptoms and Risk of Dementia, University of New South Wales, Worsening Depression, Worsening Depression and Elevated Dementia Risk
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Severe, Persistent and Fatal Delirium (Dementia and Geriatric Cognitive Disorders Extra)
Summary Delirium is typically a transient syndrome, but this study concentrates on severe persistent and potentially fatal delirium. Just 15 cases are considered, involving diverse diagnoses including Alzheimer’s Disease, dementia with Lewy bodies, Creutzfeldt-Jakob disease and progressive supranuclear palsy. Full … Continue reading
Posted in Acute Hospitals, Delirium, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Quick Insights
Tagged Academic Medical Center: University of Amsterdam, Alzheimer's Disease, Amsterdam, Confusion, Confusion (Delirium), Creutzfeldt-Jakob Disease, Creutzfeldt-Jakob Disease (CJD), Delirium and Dementia With Lewy Bodies, Delusions, Dementia and Geriatric Cognitive Disorders Extra, Dementia in Creutzfeldt-Jakob disease, Dementia with Lewy Bodies, Dementia With Lewy Bodies (DLB), Department of Neurology: University of Amsterdam, DLB: Dementia with Lewy Bodies, Fatal Delirium, Hallucinations, Institution for Mental Health Care 'Dijk en Duin' (Netherlands), Netherlands, Neurodegeneration, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurological Conditions, Neurological Disease, Neuropathology, Parnassia Groep, Persistent Delirium, Progressive Supranuclear Palsy, Psychogeriatric Observation Unit: Institution for Mental Health Care 'Dijk en Duin', Severe Delirium, Severe Persistent and Fatal Delirium, University of Amsterdam
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Alzheimer’s Disease: Persistent Perplexity (BMJ)
Summary A recent British Medical Journal article examines what is known, and remains uncertain, about the pathogenesis of Alzheimer’s Disease. It also touches on the difficulty of diagnosis, and current prospects for disease-modifying treatments. Full Text Link (Note: This article … Continue reading
Posted in Acute Hospitals, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, UK
Tagged Alzheimer's Disease, Alzheimer’s Disease Biomarkers, Alzheimer’s Disease: Causes, BMJ, British Medical Journal (BMJ)
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Pharmacological Treatments for Alzheimer’s Disease in Primary Care / Management of Cognitive Symptoms (DTB / Nursing Times)
Summary A Drug and Therapeutics Bulletin (DTB) article reviews the evidence concerning drugs prescribed for cognitive symptoms in Alzheimer’s Disease and discusses some issues in their prescription. Donepezil, galantamine and rivastigmine are licensed for mild to moderate Alzheimer’s Disease in … Continue reading
Posted in Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Management of Condition, Models of Dementia Care, NICE Guidelines, Pharmacological Treatments, Practical Advice, Quick Insights, UK
Tagged Acetylcholinesterase Inhibitors (AChEIs), AChEIs, Alzheimer's Disease, Anti-Dementia Medication, Aricept, BMJ Publishing Group Ltd, Cognitive Symptoms, Donepezil, Drug and Therapeutics Bulletin (DTB), DTB, Ebixa, Eisai Ltd, Exelon, Galantamine, Management of Cognitive Symptoms, Memantine, Memantine Hydrochloride, Memory Clinic Services: Nurse Prescribing, National Institute for Health and Care Excellence (NICE), Nurse Prescribing, Nursing Times, Primary Care, Reminyl, Rivastigmine
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