Tag Archives: Alzheimer’s Gene (APOE4 Gene)

Potential Association Between Tea Consumption and a Reduced Risk of Developing Dementia? (NHS Choices / Journal of Nutrition, Health and Aging)

Summary There is some evidence from Singapore that tea drinkers may be less likely to develop brain disorders such as dementia. Researchers discovered that Chinese elderly tea drinkers appeared to be less likely to develop dementia compared to non-drinkers. “The … Continue reading

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Alzheimer’s Disease: Genetics Research Breakthrough (BBC News / NHS Choices / Nature Genetics)

Summary An international collaboration of geneticists from 145 academic institutions investigating Alzheimer’s Disease have performed a meta-analysis of data about the DNA of 17,000 patients and 37,000 healthy people. Their analysis of genome-wide association studies (GWAS) has identified 21 genetic … Continue reading

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Blood Test Could Assist Early Diagnosis of Alzheimer’s Disease (BBC News)

Summary Researchers at the University of Nottingham are developing a quick and easy blood test to detect proteins linked strongly with Alzheimer’s Disease, such as amyloid and APOE, in combination with other markers linked to inflammation. The test has not been fully validated yet, and could be … Continue reading

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Hormone Replacement Therapy to Slow Dementia Onset? (NHS Choices / PLoS One)

Summary This NHS Choices critical appraisal examines press coverage of recent research which investigated the relationship between the genetic variant APOE-e4 (which increases the risk of developing Alzheimer’s Disease), hormone replacement therapy (HRT) and telomere length (an indicator of cell … Continue reading

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Bapineuzumab: Alzheimer’s Drug Trials Halted (Healthcare Today UK)

Summary Two U.S. drug companies have halted trials of bapineuzumab, an experimental drug to treat Alzheimer’s Disease. The drug failed to produce any improvement in the symptoms of dementia sufferers. Pfizer Inc. and Johnson & Johnson had been testing bapineuzumab, which had been designed … Continue reading

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Exposure to Statins in Early Old Age May Lower Risk of Alzheimer’s Disease

[This abstract first appeared in: Dementia: the Latest Evidence Newsletter RWHT Volume 1 Issue 7 February 2011]. Abstract This US prospective cohort study looked into whether statins (simvastatin, lovastatin, pravastatin and atorvastatin) reduce the risk of Alzheimer’s Disease (AD), and investigated the influence … Continue reading

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Alzheimer’s Gene Can Effect Young People’s Brains

[This abstract first appeared in: Dementia: the Latest Evidence Newsletter RWHT Volume 1 Issue 3 October 2010]. Abstract A gene (the APOE4 gene) which carries a known risk for Alzheimer’s disease can affect the brains of healthy young people, decades before … Continue reading

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