Tag Archives: APOE Gene

One More Genetic Link in the Longevity Enigma? (BBC News / Sanger Institute / Nature Communications)

Summary People living in the isolated Greek villages of Zoniana and Anogia have a noted tendency to live well into old age. They have a lower than expected incidence of cardiovascular disease, including heart problems, heart attacks and stroke. It … Continue reading

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Alzheimer’s Disease: Genetics Research Breakthrough (BBC News / NHS Choices / Nature Genetics)

Summary An international collaboration of geneticists from 145 academic institutions investigating Alzheimer’s Disease have performed a meta-analysis of data about the DNA of 17,000 patients and 37,000 healthy people. Their analysis of genome-wide association studies (GWAS) has identified 21 genetic … Continue reading

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The Role of the APOE Gene in the Neuropsychiatric Symptoms of Late-Onset Alzheimer’s Disease

Summary Neuropsychiatric symptoms, commonly termed behavioural and psychological symptoms of dementia, occur frequently in Alzheimer’s Disease. This article reviews evidence on the likely role of the apolipoprotein E (APOE) gene in the development of neuropsychiatric symptoms in Alzheimer’s Disease, paying … Continue reading

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