Tag Archives: APOE

One More Genetic Link in the Longevity Enigma? (BBC News / Sanger Institute / Nature Communications)

Summary People living in the isolated Greek villages of Zoniana and Anogia have a noted tendency to live well into old age. They have a lower than expected incidence of cardiovascular disease, including heart problems, heart attacks and stroke. It … Continue reading

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Alzheimer’s Disease: Genetics Research Breakthrough (BBC News / NHS Choices / Nature Genetics)

Summary An international collaboration of geneticists from 145 academic institutions investigating Alzheimer’s Disease have performed a meta-analysis of data about the DNA of 17,000 patients and 37,000 healthy people. Their analysis of genome-wide association studies (GWAS) has identified 21 genetic … Continue reading

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Blood Test Could Assist Early Diagnosis of Alzheimer’s Disease (BBC News)

Summary Researchers at the University of Nottingham are developing a quick and easy blood test to detect proteins linked strongly with Alzheimer’s Disease, such as amyloid and APOE, in combination with other markers linked to inflammation. The test has not been fully validated yet, and could be … Continue reading

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Alzheimer’s Brain Plaques Cleared Rapidly by Cancer Drug in Mice (BBC News / NHS Choices)

Summary Clumps of a protein called beta-amyloid are a feature of Alzheimer’s Disease. The clearance of these plaques is widely thought to be a promising target for Alzheimer’s research. It has now been found that the destructive plaques found in the … Continue reading

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Genes Involved in Late-Onset Alzheimer’s Disease Identified (Genome-Wide Association Studies)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 1 Issue 10, May 2011]. Abstract Five further genes which increase the risk of developing late-onset Alzheimer’s Disease have been identified, taking the number of identified … Continue reading

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