Tag Archives: Bazian

Time for a Complete Reset in Alzheimer’s Disease / Dementia Drugs Research: Never Too Late? (BBC News / Brain / NHS Digital)

Posted on May 1, 2019 by Dementia and Elderly Care News

Summary A new type of dementia, previously misdiagnosed as Alzheimer’s Disease, has been discovered to be prevalent in the oldest of old persons. Perhaps a third of elderly people earlier thought to have Alzheimer’s Disease may have had Limbic-predominant age-related … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged Amnestic MCI, Australia, Austria, Bazian, BBC Health News, Behind the Headlines, Brain (Journal), Central Clinical School Faculty of Medicine and Health (Sydney Australia), Clinical and Neurocognitive Features of LATE, Consensus Guidelines for LATE-NC Staging, Consensus Proposed LATE-NC TDP-43 Stages, Dementia-Related Misdiagnosis, Differential Diagnosis, Drug Trials, Drug Trials Failure Rate, Emory University (Atlanta), FTLD-TDP: Frontotemporal Lobar Degeneration With TDP-43 Proteinopathy, Harvard University, Hippocampal Atrophy, Illinois Institute of Technology, Institute of Neurology: Medical University of Vienna, Japan, LATE Biomarkers, LATE Neuropathological Change (LATE-NC), LATE Working Group, Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE), Mayo Clinic (Jacksonville), Mayo Clinic: Rochester, Medical University of Vienna, Misdiagnosis, Misdiagnosis (Potential), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuropathology, Neuropathology in FTLD-tau and FTLD-TDP, Newcastle University, NHS Digital (Formerly NHS Choices), Oldest Old, Oldest Old Age, Oldest People With Dementia, Prevalence of Dementia in Oldest Old, Public Health Impact of LATE, Recommendations for Routine Autopsy Evaluation and Classification of LATE-NC, Rush University Medical Center, Stanford University, Subtypes of Dementia, Sweden, TDP-43 Protein, TDP-43 Proteinopathy, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, United States, University of California, University of Cambridge, University of Kentucky, University of Minnesota, University of Pennsylvania, University of Southern California, University of Sydney Brain and Mind Centre, University of Texas Southwestern Medical Center, University of Washington, Uppsala University, USA | Leave a comment

The Estimated Health Impact of Poor Diets (BBC News / Lancet / NHS Digital)

Posted on April 9, 2019 by Dementia and Elderly Care News

Summary Poor diet has been estimated to be a bigger killer than smoking. Malnutrition (resulting from poor quality diets) may play a role in one in five premature deaths world-wide; an estimated 11 million people. The most dangerous diets contain: … Continue reading →

Posted in BBC News, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Statistics, Systematic Reviews, Universal Interest | Tagged Avoidable Premature Mortality, Bazian, BBC Health News, Behind the Headlines, Bill and Melinda Gates Foundation, Cancer Risk Factors, Cardioprotective Diet, Causes of Premature Mortality, Critical Appraisals, Diet, Diet and Nutrition, Diet High in Sugar-Sweetened Beverages, Diet-Related Deaths, Diet-Related Ill Health, Dietary Factors, Dietary Fibre, Dietary Interventions, Dietary Patterns, Dietary Risk Factors, Epidemiology, Epidemiology and Statistics, Flexitarian Diets, Food and Diet, Food Frequency Questionnaires, Fruit and Vegetables Intake, GBD 2017 Diet Collaborators, GBD Regions, Global Burden of Disease 2017 Diet Collaborators, Global Burden of Disease Study, Global Burden of Disease Study (GBD), Global Burden of Disease Study 2017, Healthy Ageing, Healthy Behaviour, Healthy Diet, Healthy Eating, Healthy Lifestyles, High in Fat Salt and Sugar (HFSS), Institute for Health Metrics and Evaluation (IHME): University of Washington, Institute for Health Metrics and Evaluation (IMHE), Institute for Health Metrics and Evaluation (Seattle), Lancet, Malnutrition, Malnutrition in the Community, Mediterranean and DASH (Dietary Approaches to Stop Hypertension) Diets, Mediterranean and DASH Diets, Mediterranean Diet, National Nutrition Surveys, Neuroprotective Diets, NHS Digital, NHS Digital (Previously NHS Choices), Non-Communicable Diseases (NCD), Nutrients, Nuts, Omega-3 Fatty Acids, Poor Diets, Premature Death, Premature Mortality, Processed Foods, Processed Meats, Red Meat, Reducing Avoidable Premature Mortality, Reducing Premature Mortality, Salt, Salt Reduction, Seeds, Sodium Intake, Southern Mediterranean Countries, Suboptimal Diets: Risk Factor for Non-Communicable Diseases (NCDs), Systematic Reviews and Meta-Analyses, Trans Fatty Acids, Type 2 Diabetes, Type 2 Diabetes: Prevention, Vegetables, Whole Grains, Wholegrains | Leave a comment

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

Posted on March 20, 2019 by Dementia and Elderly Care News

Summary Further discussion about the possibilities of using inexpensive eye tests to detect Alzheimer’s Disease, perhaps years before symptoms appear. This particular technique involves the examination of blood vessels and blood flow in the retina, as detected by Octa (Optical … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged Alzheimer's Disease: Diagnosis, Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease Biomarkers, Assessment and Diagnosis, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Central Subfield Thickness (CST), Cognitive Impairment, Critical Appraisals, Dementia Case Finding, Dementia Diagnosis, Dementia Screening, Diagnosis, Diagnosis of Alzheimer's Disease, Diagnostics, Duke University in North Carolina, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Treatment Diabetic Retinopathy Study, Eye Examinations, Foveal Avascular Zone (FAZ) Area, Karen L. Wrenn Alzheimer's Disease Award, Macular Ganglion Cell-Inner Plexiform Layer (GC-IPL), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment, National Institutes of Health, National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Digital (Formerly NHS Choices), Non-Invasive Biomarkers, Octa: Optical Coherence Tomography Angiography, Ophthalmology Retina, Optical Coherence Tomography, Optical Coherence Tomography Angiography (OCTA), Preclinical Alzheimer's Disease, Rapid Screening, Research to Prevent Blindness Inc. (New York), Retina as Early Biomarker of Neurodegeneration, Retinal Biomarkers, Retinal Examination in Neurodegenerative Diseases, Retinal Microvascular and Neurodegenerative Changes in Alzheimer’s Disease, Retinal Microvascular and Neurodegenerative Changes in Mild Cognitive Impairment, Retinal Vessel Density (VD), Screening, Screening for Dementia, Timely Diagnosis, US National Institutes of Health (NIH), USA | Leave a comment

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Posted on January 28, 2019 by Dementia and Elderly Care News

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged APP or PSEN Mutations, Australia, Basel, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Columbia University Medical Center, Dementia Research Centre, Dementia Research Centre: University College London, Department of Biomedical Sciences: Macquarie University, Department of Cellular Neurology: Hertie Institute for Clinical Brain Research, Department of Neurodegeneration: Queen Square Institute of Neurology, Department of Neurology: Columbia University Medical Center, Department of Neurology: Keck School of Medicine at USC, Department of Neurology: Ludwig-Maximilians-Universität München, Department of Neurology: Massachusetts General Hospital, Department of Neurology: Mayo Clinic Jacksonville, Department of Neurology: Washington University School of Medicine, Department of Neuroscience: Icahn School of Medicine at Mount Sinai, Department of Psychiatry and Psychotherapy: University of Tübingen, Department of Radiology: Washington University School of Medicine, Departments of Medicine Biomedicine and Clinical Research: University Hospital Basel, Division of Biostatistics: Washington University School of Medicine, Dominantly Inherited Alzheimer Network, Dominantly Inherited Alzheimer Network (DIAN), Dominantly Inherited Alzheimer's Disease, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Edith Cowan University: Western Australia, Florey Institute of Neuroscience and Mental Health: University of Melbourne, German Center for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Germany, Harvard Medical School, Hereditary Alzheimer's Disease, Hertie Institute for Clinical Brain Research, Icahn School of Medicine at Mount Sinai (New York), Indiana Alzheimer Disease Center and Department of Pathology and Laboratory Medicine: Indiana University School of Medicine, Indiana University School of Medicine, Ludwig-Maximilians-Universität München, Macquarie University, Macquarie University (New South Wales), Massachusetts General Hospital, National Institute on Aging, National Institute on Aging (NIA), National Institute on Aging (US), Nature Medicine, Neurodegeneration Division: The Florey Institute of Neuroscience and Mental Health, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurofilament Light Chain (NfC), Neurofilament Light Chain (NFL), Neurofilament Light Protein (NF-L), Neurofilament Light Protein in Blood: Potential Biomarker of Neurodegeneration, Neurologic Clinic and Policlinic: University Hospital Basel, Neuroscience Research Australia, Non-Invasive Biomarkers, Plasma Biomarkers, Preclinical Alzheimer's Disease, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, School of Medical Health and Sciences: Edith Cowan University, School of Medical Sciences: University of New South Wales, Serum Neurofilament Light Chain Protein, Switzerland, Taub Institute for Research on Alzheimer's Disease and the Aging Brain: Columbia University Medical Center, United States, University College London, University Hospital Basel, University of Basel, University of Melbourne, University of New South Wales, University of Tübingen, US National Institute on Aging, USA, Warren Alpert Medical School of Brown University, Washington University School of Medicine | Leave a comment

Further Evidence on the Association Between Poor Oral Health and the Risk of Developing Alzheimer’s Disease. New Possibilities for Treatment? (BBC News / Science Advances)

Posted on January 25, 2019 by Dementia and Elderly Care News

Summary Analysis of brain tissue, spinal fluid, and saliva from persons with Alzheimer’s Disease indicates the presence of Porphyromonas gingivalis (the bacterium associated with chronic gum disease) in the brain and central nervous system. Animal research using mice indicates that … Continue reading →

Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Alzheimer's Disease and Chronic Periodontitis, Alzheimer's Disease Causation and Possible Treatments, Alzheimer’s Disease, Amyloid Beta, Amyloid Beta Protein, Arginine-Gingipain A (RgpA), Arginine-Gingipain B (RgpB), Australia, Bazian, Behind the Headlines, Beta-Amyloid Plaques, Chronic Gum Disease, Chronic Periodontitis, Common Oral Problems and Risk Factors, COR271, COR388, Cortexyme, Dementia Risk Factors, Dental Healthcare, Dental Hygiene, Evidence for Risk Factors of Dementia, Gingipain, Gingipain Inhibitors, Gum Disease, Gum Disease (Periodontitis), Gum Disease Bacteria, Harvard University School of Dental Medicine, β-Amyloid Plaques, Jagiellonian University (Poland), Lysine-Gingipain (Kgp), Mice, Modifiable Risk Factors, Neuroprotective Agents, New Zealand, Oral Health in Older Adults, Oral Healthcare, Oral Hygiene, P. gingivalis, Periodontitis, Periodontitis and Risk of Developing Alzheimer’s Disease, Poland, Porphyromonas gingivalis, Porphyromonas Gingivalis in Alzheimer’s Disease, Risk Factors, Science Advances (Journal), Small-Molecule Gingipain Inhibitors: Possibly Neuroprotective, Tau Tangles, Transgenic Mice, University of Auckland, University of California, University of Louisville School of Dentistry, University of Melbourne | Leave a comment

Brain Training in Later Life: Limited Value for Prevention of Cognitive Decline? (BBC News / BMJ / NHS Digital)

Posted on December 11, 2018 by Dementia and Elderly Care News

Summary A Scottish study indicates that self-reported intellectual engagement (in the form of performing puzzles, crosswords and other problem-solving activities) during later life has little influence on the trajectory of decline of memory or mental processing speed. The cognitive reserve … Continue reading →

Posted in Alzheimer’s Research UK, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Scotland, UK, Universal Interest | Tagged Aberdeen Birth Cohort Studies, Alzheimer's Research UK, Bazian, BBC Health News, Behind the Headlines, Biology and Biotechnology Science Research Council, BMJ, BMJ Publishing Group Ltd, Brain Training, British Medical Journal (BMJ), Cognitive Decline, Cognitive Decline Studies, Cognitive Impairment, Cognitive Impairment (Potential Risk and Protective Factors), Cognitive Interventions, Cognitive Reserve, Cognitive Reserve Hypothesis, Cognitive Stimulation, Cognitive Training, Cognitive Training Exercises, Cognitively Stimulating Activities, Critical Appraisals, Curiosity (Openness), Dementia Risk Reduction and Prevention, Department of Psychology: National University of Ireland, Department of Psychology: University of Aberdeen, Engage Your Brain: GCBH Recommendations on Cognitively Stimulating Activities, Enjoyment and General Engagement, Global Council on Brain Health (GCBH), Healthy Ageing, Healthy Behaviours, Healthy Lifestyles, Healthy Living, Henry Smith Charity, Hobbies and Interests, Institute of Applied Health Sciences: University of Aberdeen, Intellectual Engagement (Self-Reported), Ireland, Lifelong Learning, Meaningful Activity, Meaningful Activity and Occupation, Meaningful Occupation, Medical Research Council, Mentally Challenging Occupations, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Modifiable Risk Factors, National University of Ireland (Galway), Neuroprotective Lifestyles, NHS Grampian (Aberdeen), Positive Engagement, Problem-Solving Skills, Progression of Mild Cognitive Impairment, Rates of Conversion From Mild Cognitive Impairment to Dementia, Scottish Government Health Department, Scottish Mental Health Survey of 1947, Skills and Hobbies, Slowing of Cognitive Decline, University of Aberdeen, Use It or Lose It Hypothesis, Use It or Lose It Hypothesis: Benefit of Cognitively Stimulating Activity, Wellcome Trust | Leave a comment

Mediterranean Diets: Good for Mental Health? (BBC News / Molecular Psychiatry / NHS Choices)

Posted on September 26, 2018 by Dementia and Elderly Care News

Summary Mediterranean diets may help to prevent depression, according to a new meta-analysis of 41 earlier studies. More research is needed to confirm this suspected link. Full Text Link Reference Mediterranean diet ‘may help prevent depression’. London: BBC Health News, … Continue reading →

Posted in BBC News, Community Care, Depression, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Statistics, Systematic Reviews, UK, Universal Interest | Tagged Academy of Finland, Anti-Inflammatory Diets, Association Between Inflammation and Depression, Australia, Avoidance of Pro-Inflammatory Diets, Bazian, Beans, Behind the Headlines, Brown Rice It also contains moderate amounts of fish, Cereal Products, Cereals, Critical Appraisals, Deakin University, Dietary Approaches to Stop Hypertension (DASH), Dietary Behaviour, Dietary Factors, Dietary Indices, Dietary Inflammatory Index (DII), Dietary Patterns, Dietary Recommendations, Dietary Risk Factors, Epidemiology, Epidemiology and Statistics, Food and Diet, France, Fruit and Vegetables, Fruits, Gut Microbiome, Healthy Eating, Healthy Eating Index (HEI), Human Gut Microbiome: a Potential Risk Factor for Depression, Human Gut Microbiome: a Potential Risk Factor for Mental Ill-Health, Inflammation, Inflammatory Potential of Diet, Medical Research Council, Mediterranean and DASH Diets, Mediterranean Diet, Modifiable Risk Factors, Molecular Psychiatry (Journal), Nordforsk, Nutrition, Nutrition and Depression, Nutrition and Mental Health, Nutrition and Wellbeing, Nutritional Needs, Olive Oil, Oxidative Stress, Pasta, Plant-Rich Diets, Prevention, Risk Factors for Depression, Spain, Systematic Reviews and Meta-Analyses, University College London, University of Las Palmas de Gran Canaria, University of Montpellier, White Meats, Wholegrain Bread | Leave a comment

Tag Archives: Bazian

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Further Evidence on the Association Between Poor Oral Health and the Risk of Developing Alzheimer’s Disease. New Possibilities for Treatment? (BBC News / Science Advances)

Brain Training in Later Life: Limited Value for Prevention of Cognitive Decline? (BBC News / BMJ / NHS Digital)

Mediterranean Diets: Good for Mental Health? (BBC News / Molecular Psychiatry / NHS Choices)

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