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Tag Archives: Benzodiazepines
Potential Harms From Polypharmacy in the Elderly (BBC News / Age UK / EJCP / Bazian / Lancet Psychiatry)
Summary An Age UK report investigates the potential harms of over-prescribing medicines for older people. Older persons often remain on too many prescribed medicines, putting them at risk of side-effects, potentially resulting in falls and other forms of serious harm. … Continue reading →
Posted in Age UK, Antipsychotics, BBC News, Charitable Bodies, Commissioning, Community Care, Depression, Falls, Falls Prevention, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Hypertension, In the News, Integrated Care, Management of Condition, National, Personalisation, Pharmacological Treatments, Quick Insights, UK, Universal Interest
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Tagged Achieving Better Value, Addictions Department - Division of Academic Psychiatry: King's College London, Addictive Prescription Medicines, Adverse Drug Reactions (ADRs), Adverse Drug Reactions in the Elderly, Ageing Population, Alcohol Drugs Tobacco and Justice Division: Public Health England, AntiCholinergic Burden, Anticholinergic Drugs, Anticholinergics, Antidepressants, Anxiolytics and Hypnotics (Including Benzodiazepines), ARMOUR Tool, Australian Prescribing Indicators, Austrian Criteria, Barenholtz Levy, Bazian, BBC Health News, Beers Criteria, Behind the Headlines, Benzodiazepines, Better Value, Better Value Healthcare, Better Value in the NHS, Brown Model, Cantrill Indicators, Care Home Pharmacists, Care Home Pharmacists to Cut Overmedication, Care Homes, Care of Frail Older People With Complex Needs, Care of Older People Living at Home, Care of Older People Living in Care Homes, Care Planning: Relating New Prescribing Decisions to Existing Medicines, Care Quality Improvement Department: Royal College of Physicians, Case Management and Enhanced Rapid Response, Challenging Behaviour in Dementia, Choosing Wisely, Choosing Wisely in the NHS, Choosing Wisely in the UK, Clinical Pharmacists, CMS List, Communication Between Community Pharmacists and GPs, Community Pharmacies, Community Pharmacists, Community Pharmacy, Community-Based Services, Community-Based Support, Comorbidity, Comorbidity and Dementia, Comorbidity and Polypharmacy in People With Dementia, Dementia Friendly Community Pharmacists, Department of Family Medicine: University of California Los Angeles, Department of Primary Care and Public Health: Imperial College London, Dependence and Withdrawal Associated With Prescribed Medicines (PHE Review), Deprescribing, Discontinuation of Multiple Medications in Older Adults, Doubling-Up, Drug Burden Index, Drug Cost Savings, Economic Sustainability, Elderly Malnutrition, European Journal of Clinical Pharmacology, FORTA Criteria, Four or More Medicines (FOMM) Support Service, Frail Older People, Frailty, Gabapentinoids, Geriatric Medication Algorithm, German PRISCUS List of Potentially Inappropriate Medications, Good Practice in Care Homes, Guy's and St Thomas' NHS Foundation Trust, Hamdy Criteria, Hanoi Medical University, Harms of Too Much Medicine, Health Improvement Directorate: Public Health England, High Quality Medicines Reviews, Holmes Criteria, Hospital Pharmacists, Hospital‑Based Multidisciplinary Teams: Pharmacists, Hull-York Medical School: University of Hull, Imperial College London, Improving Care for Frail Older People, Improving Patient Safety, Improving Pharmaceutical Care in Care Homes, Improving Prescribing in the Elderly Tool, Improving Prescribing Practice, Improving Standards in Care Homes, Inappropriate Drug Use, Inappropriate Medication, Inappropriate Prescribing, Institute of Psychiatry Psychology and Neuroscience: King’s College London, Integrated Care Clinical Pharmacist (ICP) for Frail Older People, Integrated Care Pharmacists (ICPs), Kaiser Permanente Model, Kings College London, KPC Criteria, Lambeth Addictions: South London and Maudsley NHS Mental Health Foundation Trust, Lancet Psychiatry, Laroche Criteria, Later Life, Lechevallier Criteria, Less is More, Liaison and In-Reach Services for Frail Older People, Lindblad’s List, Lipton’s Tool, Living at Home, Living Well in Care Homes, Long-Term Conditions (LTCs), Lowering Costs, Maio Criteria, Malnutrition, Malnutrition in Later Life, Malone’s List, Management of Challenging Behaviour, Managing Comorbidity and Complexity, Managing Medicines in Care Homes, Matsumura Alert System, McLeod Criteria, MDTs: Multidisciplinary Teams, Medical Overuse, Medication Adherence, Medication Appropriateness Index, Medication Creep, Medication Nonadherence, Medication Reviews, Medication Reviews in Care Homes, Medication Without Harm (WHO), Medication-Related Harm, Medications Management Outcome Monitor, Medicine Combinations, Medicines Management, Multi-Morbidities, Multimorbidities and Long-Term Conditions, Multiple Comorbidities, Multiple Long-Term Conditions, Multiple Medications (Polypharmacy), National Guideline Centre: Royal College of Physicians, NCOA Criteria, New Mexico Criteria, NHS Business Services Authority (NHSBSA), NHS Community Pharmacies, Non-Adherence: Medication-Related Harm, Norwegian General Practice (NORGEP) Criteria, Oborne’s Prescribing Indicators, Older Adults Higher Levels of Dependency Dementia and Comorbidity, Older People, Older People Supported and Involved in Decisions About Medicines, Older People With Complex Needs, Older People's Care, Opioid Painkillers, Opioids, Optimising Prescribing and Deprescribing in Older Adults, Over-Medication, Over-Prescribing, Over-Treatment, Overdiagnosis and Overtreatment, Overmedicalization, Overmedicaton in Care Homes, Overprescribing, Overprescription, Overuse of Medication, Owen’s Steps, Patient Harms, Patient Preference and Adherence, Patient Safety, Patients With Polypharmacy Risks, People With Dementia Living at Home, Pharmacist-Led Care Home Medication Reviews, Pharmacist-Led Home Medication Reviews, Pharmacist-Led Information Technology Intervention (PINCER), Pharmacist-Led Medication Reviews, Pharmacists, Pharmacists to Cut Unnecessary Hospital Admissions, PINCER, PINCER Intervention, PMDRP, Polypharmacy, Polypharmacy and Frailty, Polypharmacy in the Elderly STOPP and START Criteria, Poor Medicines Management, Potentially Inappropriate Medications (PIMs), Potentially Inappropriate Medications in the Elderly: the PRISCUS List, Potentially Inappropriate Medicine Combinations, Potentially Inappropriate Prescribing, Potentially Inappropriate Prescribing (PIP), Potentially Inappropriate Prescribing in Older People With Dementia, Prescribing Cascades, Prescribing Optimisation Method, Prescription Drugs, Prescription Drugs Dependency, Prescription Drugs: Long-Term Use, Prescription of Psychotropic Drugs, Prevalence of Potentially Inappropriate Prescribing in Older People With Dementia, Preventable Hospital Admissions, Preventative Care, Preventing Acute Admissions from Care Homes, Prevention, Prevention of Avoidable Emergency Admissions: Proactive Management of Long-Term Conditions, Preventive Care, Primary Care, Primary Care Adverse Drug Reactions, PRISCUS List, Proactive Specialist In-Reach, Professor Paul Cosford: Director for Health Protection and Medical Director at Public Health England, Protecting Resources and Promoting Value, Psychotropic Drug Cessation, Psychotropic Drugs, Public Health England, Rancourt Criteria, Reducing Inappropriate Polypharmacy, Reducing Prescribing Costs, Reducing Unplanned Hospital Admissions, Reducing Waste in the NHS, Reducing Wasted Medications, Robertson’s Flow Charts, Royal College of Physicians, School of Preventive Medicine and Public Health: Hanoi Medical University, Sloane List, Social Prescribing, Social Prescribing Approach to Reducing Default to Medicines / Drug-Based Treatments, South London and Maudsley NHS Mental Health Foundation Trust, START Criteria, STOPP and START Criteria, STOPP Criteria, STOPP START Criteria, Suboptimal Prescribing, Summary Care Records, Summary Care Records (SCRs), Sustainability, Sustainability in the NHS, Thinking Like a Patient and Acting Like a Taxpayer, TIMER Tool, Too Much Medicine, Tools for Measuring Potentially Inappropriate Prescribing in Older People With Dementia, Transforming Care for Frail Older People, United States, University of California Los Angeles, University of Hull, Unnecessary Hospital Admissions, Unsafe Drug Combinations, USA. Fielding School of Public Health: University of California Los Angeles, Value for Money, Value Improvement, Vietnam, Wellbeing in Care Homes, Wolfson Centre for Palliative Care Research: University of Hull, Z-Drugs (Sleeping Tablets), Zhan Criteria
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Clinical Anxiety as a Dementia Risk Factor? (BMJ Open)
Summary There are some indications that anxiety in midlife is associated with an increased risk of dementia, even after allowing for any anxiety which might have been expected to arise as a result of prodromal cognitive decline / pre-clinical dementia. … Continue reading →
Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Mental Health, Quick Insights, Statistics, Systematic Reviews, UK, Universal Interest
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Tagged Anxiety, Anxiety Disorders, Anxiety Disorders and Dementia, Anxiety: Potential Dementia Risk Factor, Benzodiazepines, Benzodiazepines and Dementia, BMJ Open, BMJ Publishing Group Ltd, Clinical Anxiety: Possible Dementia Risk Factor, Dementia Risk Factors, Diseases and Medical Conditions Associated With Increased Risk of Mild Cognitive Impairment (MCI), Division of Psychiatry: University College London, Faculty of Medicine: University of Southampton, MCI: Mild Cognitive Impairment, Midlife Anxiety, Mild Cognitive Impairment (MCI), Newcastle-Ottawa Scale, Overlapping Risk Factors, Personality (Risk Factor), Psychosocial Protective and Risk Factors, Risk Factors, Risk Factors for Alzheimer's Diseease, Systematic Review, University College London, University of Southampton
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Our Invisible Addicts: Updated Edition (Royal College of Psychiatrists / BBC News / ONS / Wiley)
Summary The Royal College of Psychiatrists has published a second edition of the “Our Invisible Addicts” report, which presents updates to evidence concerning mental health aspects of alcohol and substance misuse in the “baby boomer” generation. It advises that substance … Continue reading →
Posted in Acute Hospitals, BBC News, Commissioning, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Integrated Care, Management of Condition, Mental Health, National, Person-Centred Care, Quick Insights, Royal College of Psychiatrists, Standards, Statistics, UK, Universal Interest
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Tagged Addressing Problematic Opioid Use in OECD Countries (OECD 2019), Ageing Population, Alcohol Drugs and Tobacco, Alcohol Misuse, Alcohol Misuse Services for Older People, Alcohol Neurotoxicity, Alcohol Services, Alcohol-Related Brain Damage, Alcohol-Related Dementia, Alcohol-Related Harm, Alcoholic Dementia, Analgesic Misuse, ARBD: Alcohol Related Brain Damage, Baby Boomers, Barriers to Identification of Substance Misuse in Older People, BBC Health News, Benzodiazepines, Building Bridges Breaking Barriers (CQC), Cambridgeshire and Peterborough Clinical Commissioning Group (CCG), Castle Craig Hospital, Clinical Guidelines on Drug Misuse and Dependence Update 2017: Independent Expert Working Group, Codeine, DAPA-PC: Drug Abuse Problem Assessment for Primary Care, Deaths Related to Drug Poisoning in England (ONS), Delirium, DWAW: Drink Wise Age Well, EMCDDA: European Monitoring Centre for Drugs and Drug Addiction, Epidemiology and Demography, Faculty of Old Age Psychiatry: Royal College of Psychiatrists, Fentanyl, GAP: Gerontology Alcohol Project, Geriatric Addiction Program (GAP), GET SMART: Geriatric Evaluation Team: Substance Misuse/Abuse Recognition and Treatment, GP Prescribing in England, Ibuprofen, International Overdose Awareness Day, JETS: Joint Emergency Teams, Joint Emergency Team (JET), KS: Korsakoff’s Syndrome, Later Life, Long-Term Ibuprofen Use, Men in Sheds, Mental Health and Illness, Model Alcohol Misuse Services for Older People, Morphine, NHS Digital, Office for National Statistics (ONS), Older Adults Support in Southwark (OASIS), Older People With Substance Misuse: Ethical and Legal Considerations, Older Persons’ Substance Misuse Working Group: Royal College of Psychiatrists, Opioid Addiction, Opioid Analgesics Dependency, Opioid Prescribing, Opioids, Organisation for Economic Co-operation and Development (OECD), OST: Opiate Substitution Treatment, Our Invisible Addicts: (Royal College of Psychiatrists), Overdose Awareness Day, Physical Complications of Substance Misuse, Policy and Public Affairs Committee (PPAC): Royal College of Psychiatrists, Practice Level Prescribing in England (NHS Digital), Premature Ageing and Mortality, Prescribed Medicines Causing Dependence or Withdrawal, Prescription Drug Misuse, Prescription Drugs Dependency, Public Health, Public Health and Substance Misuse in Older People, Public Health Research Consortium, Reducing Alcohol-Related Harm, Royal College of Psychiatrists, Royal College of Psychiatrists (RCPsych): Faculty of Old Age Psychiatry, Royal College of Psychiatrists' Older People's Substance Misuse Working Group, Royal College of Psychiatrists' Report No.CR211, South Gloucestershire Opioid Analgesics Dependency Pilot Project, SSA: Society for the Study of Addiction, Substance Misuse, Substance Misuse and Suicide, Substance Misuse in Older People, Substance Use Disorder (SUD), SUD: Substance Use Disorder, Super-Strength Painkillers, Tobacco, Tobacco Consumption, Tobacco Use Cessation in Older Adults, Traditional Opioids for Chronic Non-Cancer Pain (Untidy Unsatisfactory and Probably Unsuitable), Tramadol, UK Addiction Treatment, Wernicke-Korsakoff Syndrome, Wiley
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Reducing Antipsychotic Prescribing for BPSD (BMJ / JAMA / JAMA Psychiatry / BJCP)
Summary This BMJ “Change page” article discusses the potential harms associated with use of antipsychotics in people with dementia, and covers guidelines recommending restrictions in their use. Risperidone is the antipsychotic recommended for use in the treatment of aggression associated … Continue reading →
Posted in Acute Hospitals, Antipsychotics, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Standards, Statistics, UK
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Tagged Adverse Drug Reactions (ADRs), Adverse Drug Reactions (ADRs): Type A (Potentially Avoidable and Associated With Commonly Prescribed Medications), Adverse Drug Reactions in the Elderly, Adverse Effects, Aggression, Aggressive Behaviour, Alternatives to Antipsychotics, Antidepressants, Antihypertensives, Antipsychotic Drugs, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics Limitation in Dementia, Antipsychotics Side Effects, Antipsychotics-Related Mortality Risks, Antipsychotics: Absolute Mortality Risk Increase, Antipsychotics: Neuroleptic Sensitivity, Antipsychotics: Number Needed to Harm (NNH), Atypical Antipsychotics, Behavioural and Psychological Symptoms of Dementia (BPSD), Benzodiazepines, BMJ, BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Brief Psychosocial Treatment, British Journal of Clinical Pharmacology, British Medical Journal (BMJ), Campbell Institute (CAMH): University of Toronto, Cardiff University, Center for Clinical Management Research: Veterans Affairs Ann Arbor Healthcare System (Michigan), Center for Statistical Consultation and Research: University of Michigan, CitAD Research Group, Citalopram for Agitation in Alzheimer's Disease: CitAD Trial, Clinical Biotechnology Research Institute: Roper St Francis Healthcare (Charleston: South Carolina), College of Physicians and Surgeons of Columbia University, DART-AD: Dementia Antipsychotic Withdrawal Trial (DART-AD), Dementia Antipsychotic Withdrawal Trial (DART-AD), Department of Psychiatry: University of Michigan, Department of Psychiatry: University of Southern California, Discontinuation of Antipsychotics, Effect of Citalopram on Agitation in Alzheimer Disease (CitAD Randomized Clinical Trial), Falls Prevention, Hotchkiss Brain Institute: University of Calgary, Inappropriate Prescribing, Inappropriate Use of Antipsychotics in Dementia, International Conference on Harmonization, JAMA, JAMA Psychiatry, Johns Hopkins Bayview and Johns Hopkins School of Medicine, Johns Hopkins Bloomberg School of Public Health: Baltimore, Kings College London, Medication Reviews, National Institute for Health Research (NIHR): Mental Health Biomedical Research Centre and Dementia Unit, NEST Approach, Neuroleptic Discontinuation, Neuroleptics, New York State Psychiatric Institute, Patients’ Needs and the Environment Stimulation and Techniques (NEST), Perelman School of Medicine: University of Pennsylvania, Personalised Social Interaction, Pharmacokinetics, Polypharmacy, Potential Harms of Antipsychotic Use, Prescribing Anti-Psychotic Drugs to People with Dementia, Reducing Agitation and Distress, Reducing Antipsychotic Medication in Care Homes, Reducing Antipsychotic Prescriptions in Dementia, Reducing Inappropriate Use of Antipsychotics in Dementia, Reducing Violence and Aggression, Risperidone, Seattle Protocols, Simulated Presence Therapy, South London and Maudsley NHS Foundation Trust, Stanford University School of Medicine, United States, University Hospital Llandough (Cardiff), University of Calgary, University of Manchester, University of Michigan, University of Pennsylvania, University of Rochester School of Medicine and Dentistry, University of Southern California, University of Southern California Keck School of Medicine, University of Toronto, Violence and Aggression, Wolfson Centre for Age-Related Diseases: King’s College London
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Dementia Revealed: Dementia Guide / Toolkit for GPs (NHS England / Department of Health / RCGP)
Summary NHS England has a commitment to improve dementia diagnosis rates. NHS England has published a guide to help GPs perform better on the timely diagnosis of dementia and to offer advice on post-diagnostic support for the person with the … Continue reading →
Posted in Alzheimer's Society, Antipsychotics, Charitable Bodies, Commissioning, Community Care, Delirium, Department of Health, Diagnosis, End of Life Care, Falls, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Integrated Care, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, NHS England, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Standards, UK, Universal Interest
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Tagged 4AT Score, 4AT Screening Instrument for Rapid Initial Assessment of Delirium and Cognitive Impairment, Abbreviated Mental Test Score (AMTS), ACE III: Modified Addenbrooke’s Test, Activities of Daily Living (ADLs), Acute Change or Fluctuating Course, Addenbrooke's Cognitive Examination (ACE), Advance Decision to Refuse Treatment (ADRT), Advance Directives, Agitation, Alcohol Consumption, Alcohol Misuse, Alistair Burns: NHS England’s National Clinical Director for Dementia, Alternatives to Medication for Agitation, AMT4 (Abbreviated Mental Test - 4), Anticholinergic Drugs, Anticholinergics, Antipsychotics Limitation in Dementia, Antipsychotics: Neuroleptic Sensitivity, AT4 (Delirium Scale), Behavioural and Psychological Symptoms of Dementia (BPSD), Benefits Advice, Benzodiazepines, BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Care Homes, Caregiver Assessments, Carers' Assessments, Clomethiazole, Coding of Dementia, Cognitive Stimulation Therapy (CST), Dementia and Alcohol, Dementia and Driving Guidance, Dementia Coding, Dementia Diagnosis Rates, Dementia Prevalence Calculator, Dementia Revealed: Dementia Guide for GPs, Dementia Toolkit for GP Commissioners, Dementia Toolkit for GPs, Deprivation of Liberty Safeguards (DoLS), Diagnosis and Assessment, Diagnosis and Referral, Diagnosis and Support, Diagnosis at Primary Care Level, Dr Elizabeth Barrett: Shires Health Care (Hardwick CCG), Driving, Driving and Dementia, Early Diagnosis, Fluctuation Assessment Scales, Fluctuations, General Practice, General Practice in England, General Practices, General Practitioner Assessment of Cognition (GPCOG), Geriatric Depression Scale, GPCog (The General Practitioner assessment of Cognition), GPs' Dementia Toolkit, IMCAs and Safeguarding, Improving Coding, Improving Dementia Diagnosis Rates, Improving General Practice, Inappropriate Use of Antipsychotics in Dementia, Independent Mental Capacity Advocates (IMCAs), Lasting Power of Attorney (LPoA), Lorazepam, Low Dose Antipsychotics, Managing Agitation, Memantine, Memory Clinics, Mini Mental State Examination (MMSE), Mirtazapine, Montreal Cognition Assessment (MOCA), NHS Continuing Care, NHS Hardwick CCG, Post-Diagnosis Support, Post-Diagnostic Support, Primary Care, Professor Alistair Burns, Quetiapine, RCGP, Risperidone, Rivastigmine, Royal College of General Practitioners (RCGP), Safeguarding Vulnerable Adults, Sertraline, Shires Health Care, Simon Stevens: Chief Executive of NHS England (2014-), Social Services, Support for Improving Dementia Diagnosis Rates, Temazepam, Timely Diagnosis, Trazodone, Voluntary Organisations, Wernicke-Korsakoff Syndrome, Zopiclone
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Use of Benzodiazepines and Increased Risk of Alzheimer’s Disease (BBC News / BMJ)
Summary Long-term use of benzodiazepines, often prescribed for anxiety and sleep problems, appears to be linked to an increased risk of developing Alzheimer’s Disease. A French-Canadian team of researchers have found a cumulative dose-effect association between exposure to benzodiazepines (over … Continue reading →
Posted in Acute Hospitals, BBC News, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Statistics, Universal Interest
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Tagged Anxiety, Behind the Headlines, Benzodiazepine Use and Risk of Alzheimer's Disease, Benzodiazepines, BMJ, British Medical Journal (BMJ), Canada Faculty of Pharmacy: University of Montreal, Dose-Response Effect, Epidemiology, French Institute of Public Health Research (IRESP), French Ministry of Health (Direction Générale de la Santé), French National Institute of Health and Medical Research (INSERM), Funding Agency for Health Research of Quebec (Fonds de la Recherche en Santé du Québec) (FRSQ), INSERM, Inserm Research Center for Epidemiology and Biostatistics: Bordeaux, Insomnia, Institute of Health and Medical Research (Inserm), IRESP (Institut de Recherche en Santé Publique), Pharmacoepidemiology, Prescription Sleeping Pills, Quebec Health Insurance Program Database (RAMQ), Research Center of the University of Montreal Hospital Center (CRCHUM), Risk Factors, Risk Factors for Alzheimer's Diseease, Sedatives, Sleeping Pills, Sleeping Problems, Université de Bordeaux, University of Bordeaux: College of Health Sciences, University of Montreal, University of Montreal Hospital Center
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Renewed Call for Parity of Esteem for Mental and Physical Health (BBC News / Department of Health)
Summary Professor Dame Sally Davies, England’s Chief Medical Officer, has expressed support for giving mental health services a higher priority, with targets for waiting times and better protection for funding. Mental illness is estimated to cost between £70bn and £100bn … Continue reading →
Posted in Acute Hospitals, BBC News, Commissioning, Community Care, Department of Health, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Integrated Care, Management of Condition, Mental Health, National, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Pharmacological Treatments, Quick Insights, Royal College of Psychiatrists, Standards, Statistics, UK, Universal Interest
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Tagged Access to Mental Health Services, Acute Mental Health Services, Addiction to Over-the-Counter Medication, Addictions Dependence and Substance Abuse, Adult Mental Health Services, Adult Social Care, Adult Social Care Funding, Adult Social Care Services, Advice and Support, Alcohol Consumption, Alcohol Misuse, Amphetamines, Annual Report of the Chief Medical Officer 2013: Public Mental Health Priorities, APMS: Adult Psychiatric Morbidity Survey, BBC Health News, Beat, Beat (We Need to Talk), Benzodiazepines, Big Data, Big Lottery Fund National Well-being Evaluation, Black and Minority Ethnic (BME), Blood-Based Biomarkers, British Association for Counselling and Psychotherapy, British Association for Counselling and Psychotherapy (We Need to Talk), British Psychoanalytic Council, British Psychoanalytic Council (We Need to Talk), British Psychological Society, British Psychological Society (We Need to Talk), Burden of Dementia, CAMHS Transitions, Care in General Hospitals, Care Integration, CASP-19, Centre for Mental Health, Centre for Mental Health (We Need to Talk), Chief Medical Officer, Chief Medical Officer (CMO) Annual Report: Public Mental Health, Chief Medical Officer: Professor Dame Sally Davies, Child Outcomes Research Consortium (CORC), Children and Young People’s Improving Access to Psychological Therapies (CYP IAPT) Programme, Chronic Mental Health Problems, Clarity of Terminology (Improvement), Cocaine, Commissioning and Service Development, Commissioning for Parity of Esteem, Community Addictions Team (CAT), Community Care, Community Care Beds and Services, Community Mental Health, Community Mental Health Services, Community-Based Interventions, Community-Based Mental Health and Social Care Services, Community-Based Services, Community-Based Support, Conceptual Model: WHO Public Mental Health Framework, Crisis Care Concordat, Declining Investment for Elderly Mental Health, Declining Investment for Mental Health, Disease-Specific (DS-QoL), DS‑QoL, Economic Impact of Mental Health Problems, Emotional and Psychological Wellbeing, English Local Authorities, Epidemiology, Epidemiology and Statistics, Ethnic Inequalities, Foresight Report (2008), Former Minister of Care Services Norman Lamb, Funding, Funding and Investment, Funding Gaps, Future of Mental Health, Genetics, Genome-Wide Association Studies (GWAS), Health and Social Care, Health and Social Care Integration, Health Education England, Health-Related (HR-QoL), Hospital Liaison, Hospital Liaison Psychiatry Services, HR-QoL, IAPT: Improving Access to Psychological Therapies, Impact of Poor Mental Health on Physical Health, Improving Access to Psychological Therapies (IAPT) Programme, Integrated Physical and Mental Health, Integration of Health and Social Care, Investment in Adult Mental Health Services, Joint Strategic Needs Assessment (JSNA), Ketamine, King’s Health Partners Academic Health Science Centre, King’s Health Partners Alcohol Strategy, Legal Highs, Lib Dem Conference (2014), Life Course Approach, Long-Term Care (LTC), Long-Term Care and Support, Long-Term Conditions (LTCs), Managing Ongoing Physical and Mental Health Conditions, Measures of National Wellbeing, Measuring National Wellbeing Programme, Measuring Wellbeing, Mental Health, Mental Health and Employment, Mental Health and Wellbeing, Mental Health Awareness, Mental Health Care, Mental Health Care and Treatment, Mental Health Co-Morbidities, Mental Health Commissioning, Mental Health Crisis, Mental Health Crisis Care Concordat, Mental Health Dementia and Neurology Intelligence Network (MHDNIN), Mental Health Dementia and Neurology Intelligence Network (MHIN), Mental Health Foundation, Mental Health Foundation (We Need to Talk), Mental Health in England, Mental Health Inequalities, Mental Health Intelligence Network, Mental Health Liaison Services, Mental Health Policy, Mental Health Promotion, Mental Health Recovery, Mental Health Research, Mental Health Research Funding, Mental Health Research in NIHR, Mental Health Services, Mental Health Strategy, Mental Health Training in GP Training, Mental Health Trusts, Mental Health Waiting Times, Mental Health Waiting Times Targets, Mental Health: Black and Minority Ethnic Communities, Mental Healthcare, Mental Illness in the NHS, Mental Illness Prevention, Mental Wellbeing, Mental Wellbeing and Older People, Mental Wellbeing and Work, Mentally Healthy Workplaces, Methadrone, MHDNIN: Mental Health Dementia and Neurology Intelligence Network, mHealth Apps, Mind, Mind (We Need to Talk), Mind the Gap, MQ: Transforming Mental Health, MQ: Transforming Mental Health (We Need to Talk), National Counselling Society, National Counselling Society (We Need to Talk), National Outcomes Frameworks Principles and Domains, Neuroimaging, Neuropsychology, NHS Funding, NHS Waiting Times, Nick Clegg: Former Deputy Prime Minister, NIHR Mental Health Research, No Health Without Mental Health, No Health Without Mental Health Strategy, Non-Prescribed Drugs, Non-Prescribed Opiates, Norman Lamb MP, Norman Lamb MP (Former Minister of State for Care and Support), Novel Psychoactive Substances, OCD Action, OCD Action (We Need to Talk), Older Adult Mental Health Services (OAMHS), Older People and Mental Health, Older People’s Mental Health Services, Opiates, OPQoL, Parity Between Mental and Physical Health, Parity of Esteem, Prescribed Opiates, Prevalence, Prevalence of Mental Illness, Preventable Hospital Admissions, Preventative Care, Prevention, Primary Care Psychiatry, Professor Dame Sally Davies, Psychological Therapies, Psychological Wellbeing, Public Mental Health, Public Mental Health Commissioning, Public Mental Health Priorities, Quality of Life, Quality of Life Indicators, Quality of Life Research, Rapid Assessment Interface and Discharge (RAID), Recovery and Rehabilitation, Rehabilitation, Relate, Relate (We Need to Talk), Rethink Mental Illness, Rethink Mental Illness (We Need to Talk), Robust Evidence-Base, Royal College of General Practitioners, Royal College of General Practitioners (We Need to Talk), Royal College of Psychiatrists (We Need to Talk), Secondary Mental Health Services, Service Gaps, Services for People with Mental Health Problems, Short Warwick-Edinburgh Mental Wellbeing Scale (sWEMWBS), Social Epidemiology, Social Exclusion, South London and Maudsley (SLaM) NHS Foundation Trust, Spending on Mental Health, St Mungo’s Broadway, St Mungo’s Broadway (We Need to Talk), Stigma and Discrimination, Street Heroin, Suicide and Self-Harm, SWEMWBS: Short Warwick-Edinburgh Mental Well-being Scale, Tavistock Centre for Couple Relationships, Tavistock Centre for Couple Relationships (We Need to Talk), Time to Change, Tobacco, Tobacco Consumption, Torbay and South Devon Integrated Care Pioneer Service in Primary Care Psychiatry, Treatment Gaps, Treatment Recovery and Rehabilitation, United Kingdom Council for Psychotherapy, United Kingdom Council for Psychotherapy (We Need to Talk), 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Pharmacological Treatments for Neuropsychiatric Symptoms in Alzheimer’s Disease (Journal of Neurology Neurosurgery and Psychiatry)
Summary This systematic review investigates the efficacy and safety of various pharmacological treatments for neuropsychiatric symptoms in Alzheimer’s Disease patients. It concludes that cholinesterase inhibitors (ChEIs) and atypical antipsychotics could improve neuropsychiatric symptoms in these patients, but with poor patient … Continue reading →
Posted in Antipsychotics, Depression, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Pharmacological Treatments, Systematic Reviews
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Tagged Adverse Drug Reactions, Adverse Effects, Adverse Events, Antidepressants, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics Limitation in Dementia, Antipsychotics Side Effects, Antipsychotics-Related Mortality Risks, Antipsychotics: Neuroleptic Sensitivity, Atypical Antipsychotics, Behavioural and Psychological Symptoms of Dementia (BPSD), Benzodiazepines, Benzodiazepines for BPSD, BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Cerebrovascular Adverse Events, ChEIs: Cholinesterase Inhibitors, China, Cholinesterase Inhibitors, Journal of Neurology Neurosurgery and Psychiatry, Memantine, Mood Stabilisers, Nanjing Medical University, Neuropsychiatric Inventory (NPI), Neuropsychiatric Symptoms in Alzheimer’s Disease, Patient Safety, Pharmacological Treatments for Neuropsychiatric Symptoms in Alzheimer’s Disease, Qingdao Municipal Hospital, Qingdao University, Serious Adverse Events, Shandong Province, Systematic Reviews and Meta-Analyses
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Recent Systematic Reviews and Meta-Analyses on Pharmacological Treatments
Some of the following articles may be available freely where indicated (depending on local circumstances). Access to the full-text of the other articles will require a suitable Athens password, a journal subscription or payment. The Bibliographic Citations Irwin, RW. Brinton, … Continue reading →
Posted in Antipsychotics, For Doctors (mostly), For Researchers (mostly), International, Mental Health, Pharmacological Treatments, Systematic Reviews
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Tagged Allopregnanolone, Anticholinergic Discontinuation, Bacopa Monnieri Extract, Benzodiazepines, Benzodiazepines and Dementia, Benzodiazepines for BPSD, Blood Pressure, Cannabinoids (Medical), Chinese Medicinal Plants, Curcumin, Dexmedetomidine, Drug Cessation, Hypertension, Latrepirdine (Dimebon), Medical Cannabinoids, Secretase Inhibitors, Systematic Reviews and Meta-Analyses, Traditional Chinese Medicine (TCM)
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Pharmacotherapies for Sleep Disturbances in Alzheimer’s Disease (Cochrane Database)
Summary This systematic review investigates the efficacy and adverse effects of drug treatments for sleep disturbances in Alzheimer’s Disease. The authors comment on the lack of evidence to guide drug treatment of sleep problems in Alzheimer’s Disease. Full Text Link … Continue reading →
Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments, Systematic Reviews, UK
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Tagged Atypical Antipsychotics, Benzodiazepines, Circadian Disturbances in People with Dementia, Circadian Rhythms, Cochrane Database, Cochrane Database of Systematic Reviews, Daytime Sleepiness, Division of Sleep Medicine: Boston MA, GABAergic Drugs, Hypersomnia, Hypnotic Drugs, Insomnia, Melatonin, National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’sDisease and RelatedDisorders Association (NINCD-ADRDA), Nocturnal Wandering, Non-Benzodiazepine Hypnotics, Oxford Health NHS Foundation Trust, Oxford University, Parasomnia, Pharmacotherapies for Sleep Disturbances in Alzheimer’s Disease, Ramelteon, Rebound Insomnia, Reduced Nocturnal Sleep Time, Rest-Activity and Sleep-Wake Cycles, Sedating Antidepressants, Sleep, Sleep Disturbances, Sleep Disturbances in Alzheimer’s Disease, Sleep Fragmentation, Somnolence, Sundowning, Suprachiasmatic Nuclei (SCN) in the Hypothalamus, Systematic Reviews and Meta-Analyses, Trazodone, Zaleplon, Zolpidem, Zopiclone
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