Tag Archives: Biomarkers Predicting Cognitive Decline and Alzheimer’s Disease

Dementia Biomarkers Re-Explored? (General Psychiatry / JGCR)

Summary A recent systematic review examines biomarkers, as strictly defined, for neurodegenerative diseases. “Vast improvements in neuroimaging techniques have led to newly discovered biomarkers and diagnostics”. p.5 Behavioural biomarkers are mentioned hardly at all. Full Text Link Reference Maclin, JMA. … Continue reading

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Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

Summary Further discussion about the possibilities of using inexpensive eye tests to detect Alzheimer’s Disease, perhaps years before symptoms appear. This particular technique involves the examination of blood vessels and blood flow in the retina, as detected by Octa (Optical … Continue reading

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More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading

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Summary of Recent Progress in Alzheimer’s Disease Prevention Trials (CTAD / JPAD)

Summary The following article summarises a round-up of present understanding and developments reflected in current and planned prevention trials, as discussed at a EU / US / Clinical Trials in Alzheimer’s Disease (CTAD) Task Force meeting, as of December 2016-7. … Continue reading

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Screening for Dementia at the Opticians? (BBC News / NHS Choices / JAMA Neurology)

Summary A simple eye test, at high street opticians, for thinning of the retinal nerve fibre layer (RNFL) could in future help predict which persons are at risk of developing dementia. Full Text Link Reference Optician’s eye test ‘could spot … Continue reading

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Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

Summary A blood test developed by researchers in Australia and Japan appears to be able to predict the risk of developing Alzheimer’s Disease, with 90% accuracy. Detection of amyloid beta in the blood may be taken as a biomarker for … Continue reading

Posted in BBC News, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Earlier Diagnosis Research: the Deep and Frequent Phenotyping Study (BBC News / GtR)

Summary The Deep and Frequent Phenotyping Study aims to discover new ways of diagnosing dementia, ideally decades before the symptoms become apparent in order to give future drug treatments the best chance of working. The Deep and Frequent Phenotyping Study … Continue reading

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