Tag Archives: Blood-Based Biomarkers

Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Early Promising Results? (JAD / Bazian)

Summary Transcranial Electromagnetic Treatment (TEMT) for persons with mild / moderate Alzheimer’s Disease, delivered ia a bathing cap-style head device called the MemorEM, appears to bring about various statistically significant improvements without any observable adverse effects. Benefits are said to include: “ …cognitive enhancement, changes to CSF / … Continue reading

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Blood Test Able to Predict Alzheimer’s Disease Decades Before Symptoms? (BBC News / Neurology)

Summary Research published in the Neurology journal claims a significant breakthrough in the development of a blood test (for plasma Aβ42/Aβ40) which may be able to predict Alzheimer’s Disease onset with 94% accuracy. Due caution: “But it’s important to note … Continue reading

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More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading

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Summary of Recent Progress in Alzheimer’s Disease Prevention Trials (CTAD / JPAD)

Summary The following article summarises a round-up of present understanding and developments reflected in current and planned prevention trials, as discussed at a EU / US / Clinical Trials in Alzheimer’s Disease (CTAD) Task Force meeting, as of December 2016-7. … Continue reading

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Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

Summary A blood test developed by researchers in Australia and Japan appears to be able to predict the risk of developing Alzheimer’s Disease, with 90% accuracy. Detection of amyloid beta in the blood may be taken as a biomarker for … Continue reading

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No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

Summary After a near-miss mini-epidemic of Variant Creutzfeldt-Jakob Disease (vCJD) in the 1990s, experts caution that: “It is essential that we do not become complacent and continue both surveillance and risk management strategies in both human and animal prion diseases”. … Continue reading

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Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading

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