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Tag Archives: Canadian Institutes of Health Research
Maintaining Strength for Healthier Ageing (BBC News / NHS Choices / Lancet)
Summary The Chartered Society of Physiotherapy (CSP) has warned that perhaps one quarter of over-65s don’t do sufficient strength exercises to maintain general physical fitness and help avoid the risk of falls. Conducting strength exercises can be an integral part … Continue reading →
Posted in BBC News, Community Care, Falls Prevention, For Carers (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Person-Centred Care, Practical Advice, Quick Insights, Statistics, UK, Universal Interest
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Tagged .Isfahan Cardiovascular Research Center, 150 Minutes of Moderate Intensity Physical Activity Per Week (UK Government Guidance), Active and Healthy Ageing, Adults’ Health and Lifestyle, Aga Khan University, Ageing in the Community, Ageing Population, Argentina, AstraZeneca, Balance and Muscle Strength, Bangladesh, BBC Health News, Behind the Headlines, Boehringer Ingelheim, Brazil, Burnaby and Division of Cardiology: Providence Health Care (Canada), Canada, Canadian Institutes of Health Research, Cardiorespiratory Fitness (CRF), Cardiovascular Research Institute: Isfahan University of Medical Sciences, Cardiovascular Risk Factors, Carrying Shopping, Chartered Society of Physiotherapy (CSP), Chile, China, Colombia, CSP: Chartered Society of Physiotherapy, Dante Pazzanese Institute of Cardiology (São Paulo), Department of Community Health Sciences and Medicine: Aga Khan University, Department of Internal Medicine: Istanbul Medeniyet University (Turkey), Department of Social Medicine: Medical University of Wrocław, Dubai Health Authority, Dubai Medical College, Embedding Physical Activity Into Daily Life, Epidemiology, Epidemiology and Statistics, Estudios Clinicos Latinoamerica ECLA (Argentina), Eternal Heart Care Centre and Research Institute (New York), Everybody Active Every Day Campaign, Everybody Active Every Day: a Framework to Embed Physical Activity Into Daily Life, Exercise, Exercise And Lifestyle For Older People, Exercise Guidelines, Exercise Regimens, Exercises to Strengthen Muscles, Faculty of Health Sciences: Simon Fraser University, Faculty of Medicine: Istanbul Medeniyet University, Fu Wai Hospital (Chiuna), Gardening, Gardens and Health, Government Medical College (India), GSK, Hamilton Health Sciences, Hamilton Health Sciences and McMaster University, Healthy Lifestyles, Heart and Stroke Foundation of Ontario, Incidental Physical Activity, India, Institut universitaire de cardiologie et de pneumologie de Québec, International Physical Activity Questionnaire (IPQA), Iran, Isfahan University of Medical Sciences, Istanbul Medeniyet University (Turkey), King Pharma, Lancet, Lifestyle Change Programmes, Lifestyle Risk Factors, Lifting Weights, Madras Diabetes Research Foundation (India), Malaysia, McMaster University, Medical Research and Biometrics Center: National Center for Cardiovascular Diseases, Medical School Universidad de Santander: Colombia, Medical University of Wroclaw: (Poland), Mount Sinai New York Affiliate: India, Muscle Wastage, Muscle Weakness, Muscular Fitness, National Center for Cardiovascular Diseases (Chiuna), NHS Choices: Physical Activity, NHS Digital (Previously NHS Choices), Novartis), OSCAL, Pakistan, Physical Activity, Physical Activity and Cardiovascular / Non- Cardiovascular Mortality, Physical Activity and Health Benefits, Physical Activity and Occupation, Physical Activity Commitments, Physical Activity Statistics, Physical Inactivity: Social Economic and Environmental Determinant (SEED) of Health, Poland, Population Health Research Institute, Population Health Research Institute: McMaster University, Prevention of Cardiovascular Disease (CVD), Professor Karen Middleton: Chief Executive at Chartered Society of Physiotherapy, Prospective Urban Rural Epidemiologic (PURE) Study, Regular Physical Activity, Resistance Bands, Sahlgrenska Academy: University of Gothenburg, Sanofi-Aventis, School of Public Health: Postgraduate Institute of Medical Education and Research, Servier, Simon Fraser University, South Africa, Sport and Exercise Medicine (SEM), St John's National Academy of Health Sciences (Bangalore), St John's Research Institute: St John's National Academy of Health Sciences, Strength Exercises, Sweden, Turkey, United Arab Emirates, Universidad de La Frontera (Chile), University of Edinburgh, University of Gothenburg, Usher Institute of Population Health Sciences and Informatics: University of Edinburgh, Vacuuming, Xishuangbanna Prefecture: Yunnan Province (China), Yoga, Zimbabwe
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CoEN “Pathfinder” Funding for Neurodegenerative Disease Research Announced (MRC)
Summary The Centres of Excellence in Neurodegenerative Disease (CoEN) initiative has awarded £3.6 million to 11 international “Pathfinder” innovation projects. These projects aim to identify and validate new potential drugs and develop innovative therapeutic approaches for the dementia, and other conditions such … Continue reading →
Posted in Commissioning, For Researchers (mostly), In the News, International, Models of Dementia Care, Parkinson's Disease, Pharmacological Treatments, UK, Universal Interest
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Tagged Agence Nationale de la Recherche (ANR), Amyloidogenic and Inflammatory Pathways, B-Cell Activating Factor (BAFF)/A Proliferation-Inducing Ligand (APRIL) System, BAFF/APRIL, Belgium, C9orf72: Genetic Cause of Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Canada, Canadian Institutes of Health Research, Canadian Institutes of Health Research (CHIR), Centres of Excellence in Neurodegenerative Disease (CoEN), Centres of Excellence in Neurodegenerative disease (CoEN) Pathfinder Grants, CoEN Funding Partners, Dementia Research, Dementia Research Funding, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) Bonn, Disease Modifying Treatment by 2025 (Aim), Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Drug Discovery Programmes, France, French Agence Nationale de la Recherche, Genome-Wide Association Studies (GWAS), Germany, Global Action Against Dementia, Global Context, Global Leadership, Human iPSCs, Impaired Lysosomal Flux in Alzheimer’s Disease, Induced Pluripotent Stem Cells (iPSCs), Instituto de Salud Carlos III (ISCIII), International Dementia Research, iPSCs, Ireland, Italian Ministry of Health, Italy, Medical Research Council (MRC), Medical Research Council (UK), microRNA, MicroRNAs, Mitochondria, Mitochondrial Dysfunction, Mitochondrial Neurodegeneration, MRC: Medical Research Council, MT5-MMP, Mutant C9Orf72 ALS/FTD, Neurodegeneration, Neurodegenerative Disease Research, Pathfinder” Innovative Research Projects, Presymptomatic White Matter Changes in Huntington Disease, Rab GTPases, Research and Development, Research and Innovation, Research Commitment, Research Funding, Science Foundation Ireland (SFI), Slovak Ministry of Education Science Research and Sport, Slovakia, Spain, Super-Resolution STED Microscopy, Synuclein Toxicity, Synucleinopathy, Synucleinopathy Progression, Unifying Theory of Parkinson’s Disease, Vlaams Instituut voor Biotechnologie, Worms: C. elegans
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Altered Humour Predicts Behavioural Variant Frontotemporal Dementia? (BBC News / MRC / JAD / Cortex)
Summary Researchers at University College London are interested in whether sense of humour changes might help predict frontotemporal dementia (FTD). Their latest paper suggests that changes in sense of humour can be an early sign of this type of dementia, … Continue reading →
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Quick Insights, UK, Universal Interest
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Tagged Altered Humour, Altered Sense of Humour, Alzheimer's Research UK, BBC Health News, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), BV-FTD, Canadian Institutes of Health Research, Changes in Humour, Cortex (Journal), Dementia Research Centre: University College London, Dementia Research Centre: University College London: UCL Institute of Neurology: University College London, Frankly Inappropriate Humour Responses, Fronto-Temporal Dementia (FTD), Frontotemporal Dementia (FTD), Frontotemporal Lobar Degeneration, Frontotemporal Lobar Degeneration (FTLD), FTLD: Frontotemporal Lobar Degeneration, Humour in Dementia, Humour Processing in Frontotemporal Lobar Degeneration, JAD, Journal of Alzheimer's Disease, Medical Research Council (MRC), MRC, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurology, NIHR Queen Square Dementia Biomedical Research Unit, Semantic Dementia, UCL Institute of Neurology: University College London, University College London, Wellcome Trust
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The CAREDEM Case Management Modelling and Feasibility Study (HTA)
Summary The CAREDEM Case Management Study adapted a promising case management project from the USA (the PREVENT Study) and attempted to test the feasibility and acceptability of this approach to case management for dementia support in English general practice. The … Continue reading →
Posted in Commissioning, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Integrated Care, International, Management of Condition, Models of Dementia Care, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Personalisation, Quick Insights, Systematic Reviews, UK
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Tagged Admiral Nurses, Advance Care Planning, Attributes of Case Management as an Innovation (Component of Greenhalgh Diffusion of Innovation Model), BADLS: Bristol Activities of Daily Living Scale, Behavioural and Psychological Symptoms of Dementia (BPSD), Benefits of Case Management, Bristol Activities of Daily Living Scale (BADLS), Broader Context (Component of Greenhalgh Diffusion of Innovation Model), Burden on Caregivers, Canada, Canadian Institutes of Health Research, Care Co-ordination, Care Coordinators, Care Planning, CARE-DEM Research Project, CARE-DEM Study, CAREDEM Case Management Study, CAREDEM Case Manager Manual, CAREDEM Case Managers, Caregiver Burden, Caregiver Support, Carer Burden in Dementia, Carer Support, Carer Support Services, Case Management, Case Management for Dementia, Case Management for Dementia in Primary Health Care, Case Management in Primary Care, Case Management in Theory and Practice, Case Management: Design Lessons for a Definitive Trial, Case Management: Research Project Design, Case Manager Job Description, Case Manager Person Specification, Clarity of Roles and Responsibilities, CMHT: Community Mental Health Teams, Collaborative Care, Collaborative Care for People with Memory Problems, Collaborative Care Teams, Communication and Influence (Component of Greenhalgh Diffusion of Innovation Model), Community Mental Health Teams, Community Nurses as Case Managers, Community Nursing, Compatibility: Characteristics of Diffusible Innovation (in Case Management), Complexity / Ease of Use: Characteristics of Diffusible Innovation (in Case Management), Concerns of Potential Adopters (Component of Greenhalgh Diffusion of Innovation Model), Conflicting Roles (Practice Nurses), Continuity of Care, Coordinated Care, Coordinated Services, Coordination of Care, Current Controlled Trial ISRCTN74015152, Dementia Care Coordinator, Dementia Care Pathways, Dementia Navigators, Dementia Nurse Specialist, Dementia Quality of Life (DEMQOL), Dementia UK, DEMQoL: Dementia Quality of Life, Department of Family Medicine: McGill University, Diffusion of Innovation Theory, Duplication of Roles, Educational Needs Assessment for CAREDEM Case Managers, Embedding Delivery of Case Management, EQ-5D: European Quality of Life - 5 Dimensions, General Health Questionnaire (GHQ), Greenhalgh Diffusion of Innovation Model, Health and Social Care Professionals, Holistic Approaches, Image and Visibility: Characteristics of Diffusible Innovation (in Case Management), Implementation Process (Component of Greenhalgh Diffusion of Innovation Model), Individualised Support, Innovative Working (Impeded by Controlled Research?), Institute for Ageing: University of Newcastle, Institute of Health and Society: University of Newcastle, Keele University, Kings College London, Knowledge and Skills Required for Case Management, Lack of Clarity About Roles, Lack of Ownership, Linkage (Component of Greenhalgh Diffusion of Innovation Model), McGill University, MDTs: Multidisciplinary Teams, Mental Health Sciences: University College London, Methodological Problems (Case Management Research), Mini Mental State Examination (MMSE), Muddled Approaches to Case Management, Multi-Disciplinary Case Management, Named Care Coordinators, Named Case Managers, Named Contacts Providing Continuity, Named Key Worker, Named Nurses, National Institute for Health Research (NIHR) Health Technology Assessment Programme, Navigators: Coordinators of Care, Neuropsychiatric Inventory (NPI), Neuropsychiatric Inventory Scale, Newcastle upon Tyne, NHS Community Mental Health Team (CMHT) for Older People with Mental Health Problems: Unit / Reference Costs, NIHR Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), NoCLoR: North Central London Research Consortium, North Central London Research Consortium (NoCLoR), Norwich Medical School: University of East Anglia, Observability / Result Demonstrability: Characteristics of Diffusible Innovation (in Case Management), Organisational Antecedents for Innovation (Component of Greenhalgh Diffusion of Innovation Model), Organisational Readiness for Innovation (Component of Greenhalgh Diffusion of Innovation Model), Patient and Public Involvement (PPI), Patient-Carer Dyads, Personalised Case Management, Post-Diagnosis Support, Post-Diagnostic Dementia Support, Practice Dementia Registers, PREVENT Study, Primary Care, Primary Care and Health Sciences: Keele University, Proactive Care, Proactive Case Management, Reinvention: Characteristics of Diffusible Innovation (in Case Management), Relative Advantage: Characteristics of Diffusible Innovation (in Case Management), Research Department of Primary Care and Population Health: University College London, Service Continuity, Social Care Workforce Research Unit: King’s College London, Steve Iliffe: Professor of Primary Care for Older People; University College London, Support Networks, Support Networks of Case Managers, Trialability: Characteristics of Diffusible Innovation (in Case Management), University College London, University of East Anglia, University of Newcastle, Unmet Needs, Voluntariness: Characteristics of Diffusible Innovation (in Case Management)
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Cognitive and Neuroimaging Predictors of Progression from Mild Cognitive Impairment to Dementia (NHS Choices / Journal of Alzheimer’s Disease)
Summary The detection of pre-clinical Alzheimer’s Disease appears to be accomplished best by the use of a combination of information, taken from targeted neuroimaging and complementary neuropsychological assessments of cognitive functioning. This combination of approaches may be necessary in order to … Continue reading →
Posted in Acute Hospitals, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Patient Care Pathway, Quick Insights, Universal Interest
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Tagged 1Institut Universitaire de Gériatrie de Montréal, Behind the Headlines, Canada, Canadian Institutes of Health Research, Canadian Institutes of Health Research (CIHR), Cortical Thickness, Cortical Thinning, Critical Appraisals, Detection of Incipient Dementia, Heart and Stroke Foundation of Canada, Hippocampal Volume, Institut Universitaire de Gériatrie de Montréal, Journal of Alzheimer's Disease, Magnetic Resonance Imaging (MRI), MCI: Mild Cognitive Impairment, Middle Frontal Gyri, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Montréal, MRI, MRI Brain Imaging, MRI Scans, Neuroimaging, Neuropsychological Measures, Progression of Mild Cognitive Impairment to Dementia, Right Anterior Cingulate, Transition from Cognitive Impairment to Dementia, Université de Montréal, White Matter Hyperintensities
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Centrally Acting ACE Inhibitors Reduce Rate of Cognitive Decline in Dementia? (BMJ Open)
Summary It has been found that taking angiotensin-converting enzyme (ACE) inhibitors, a class of drugs which help to reduce blood pressure by relaxing the walls of blood vessels, may help to slow mental decline in people diagnosed with dementia. The … Continue reading →
Posted in For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Hypertension, In the News, International, Management of Condition, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest
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Tagged ACE Inhibitors, Angiotensin Receptor Blockers Associated with Decreased Incidence and Progression of Dementia, Antihypertensive Medications, Atlantic Philanthropies, Behind the Headlines, Blood Pressure, BMJ Open, Canada, Canadian Institutes of Health Research, Cardiovascular Health Study, Centrally Acting ACE Inhibitors, Centrally Acting ACE inhibitors (CACE-Is), Centre for Gerontology and Rehabilitation: University College Cork, Cognitive Decline, Cognitive Decline in Dementia, Cognitive Impairment, Health Services Executive Ireland, Ireland, Irish Hospice Foundation, MCI, MCI: Mild Cognitive Impairment, McMaster University: Canada, Mercy University Hospital, Mild Cognitive Impairment, NewCACE-I, ONTARGET and TRANSCEND Trials, Perindopril Protection Against Recurrent Stroke Study (PROGRESS), Quick Mild Cognitive Impairment (Qmci) Screen, St Finbarrs' Hospital: Cork City, Standardised Mini-Mental State Examination (SMMSE), Study on Cognition and Prognosis in the Elderly (SCOPE), Systolic Hypertension in Europe (Syst-Eur) Study, University College Cork
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Statins Cure for Alzheimer’s Disease: Claims Unfounded? (NHS Choices)
Summary It has recently been claimed in the press that cholesterol-lowering statin drugs might prevent the symptoms of Alzheimer’s Disease. These assertions are actually based on a small laboratory study on mice genetically modified to display signs of Alzheimer’s (specifically … Continue reading →
Posted in Animal Studies, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Proposed for Next Newsletter, Universal Interest
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Tagged Canada, Canadian Institutes of Health Research, Cholesterol Levels, Cholesterol-Lowering Drugs, Heart and Stroke Foundation of Canada, McGill University, Simvastatin, Statins, Use of Statins
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