Tag Archives: Cerebrospinal Fluid (CSF)

Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Early Promising Results? (JAD / Bazian)

Summary Transcranial Electromagnetic Treatment (TEMT) for persons with mild / moderate Alzheimer’s Disease, delivered ia a bathing cap-style head device called the MemorEM, appears to bring about various statistically significant improvements without any observable adverse effects. Benefits are said to include: “ …cognitive enhancement, changes to CSF / … Continue reading

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Early Promising Signs in Verubecestat Human Drug Trial – Since Dashed (NHS Choices / Science Translational Medicine / Translational Neurodegeneration / Biospace Inc)

Summary Early results from a Phase I trial indicate that the BACE1 inhibitor Verubecestat may effectively reduce β-amyloid formation in human patients with Alzheimer’s Disease. This appears to confirm previous trials with rats, monkeys and healthy young human adults. As … Continue reading

Posted in Animal Studies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Brain and Immune System: Not Unconnected? (NHS Choices / Nature)

Summary Researchers have discovered previously unsuspected lymphatic vessels in the outer layers of the brain. The brain and central nervous system were not previously thought to be connected to the lymphatic system, so this discovery may pave the way for … Continue reading

Posted in Animal Studies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Recent Brain Research / Neurology-Related Systematic Reviews and Meta-Analyses

Summary Recent reviews and meta-analyses on neurology-related topics are listed below. Some of these articles may be available freely (according to local circumstances). A suitable Athens password, a journal subscription or payment for access are required to obtain the full-text … Continue reading

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Social Workers (mostly), International, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Concerning the Diagnostic Accuracy of Plasma and CSF Biomarkers (Cochrane Database)

Summary This systematic review investigates the diagnostic accuracy of blood plasma and CSF Aß levels for detecting patients with mild cognitive impairment (MCI) and who are likely to progress to Alzheimer’s Disease or other types of dementia. The accuracy of … Continue reading

Posted in Charitable Bodies, Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Recent Systematic Reviews and Meta-Analyses on Diagnosis, Screening, Assessment and Symptoms

Some of the following articles may be available freely where indicated (depending on local circumstances). Access to the full-text of the other articles will require a suitable Athens password, a journal subscription or payment. The Bibliographic Citations Rosa, MI. Perucchi, … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , | Leave a comment

Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)

Summary A hypothetical model of the major biomarkers of Alzheimer’s Disease, published by the same authors in 2010, has been updated in the light of new evidence. Full Text Link Reference Jack, CR. Jr. Knopman, DS. [and] Jagust, WJ. [et … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment