Tag Archives: Cholinesterase Inhibitors

Translations of a Collection of Norwegian Dementia-Related Systematic Reviews (NIPH / JAMA Network Open)

Summary The Norwegian Directorate of Health commissioned the Norwegian Institute of Public Health (NIPH) to produce a series of evidence reviews – dating back to 2014 (and earlier) – with a view to the development of national evidence-based guidelines. These … Continue reading

Posted in Commissioning, Community Care, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Guidelines, International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Personalisation, Quick Insights, Standards, Systematic Reviews, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Dementia Drug Effective in Helping Avoid Transitions into Care Homes (MRC / BBC News / Lancet Neurology)

Summary Analysis of data from the DOMINO-AD Trial indicates that the drug Donepezil may be effective in avoiding care home admissions in more advanced cases of Alzheimer’s Disease. Discontinuation of donepezil appears to be associated with an increased risk of … Continue reading

Posted in Alzheimer's Society, BBC News, Commissioning, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Integrated Care, Management of Condition, Mental Health, Models of Dementia Care, National, Patient Care Pathway, Patient Information, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Scotland, Statistics, UK, Universal Interest | Tagged , , , , , , , , , , | Leave a comment

Weight Loss Associated with Cholinesterase Inhibitors for Dementia (Journal of the American Geriatrics Society)

Summary Research following persons with dementia aged 65 and older, between 2007 to 2010, compared weight loss in individuals prescribed cholinesterase inhibitors against weight loss in persons prescribed other medications. Individuals taking cholinesterase inhibitors had a higher risk of weight … Continue reading

Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Pharmacological Treatments, Universal Interest | Tagged , , , , , , , , , , , | Leave a comment

Recent Systematic Reviews and Meta-Analyses on Pharmacological Treatments

Some of the following articles may be available freely where indicated (depending on local circumstances). Access to the full-text of the other articles will require a suitable Athens password, a journal subscription or payment. The Bibliographic Citations Henderson, VW. (2014). … Continue reading

Posted in Antipsychotics, For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments, Systematic Reviews | Tagged , , , , , , , , , , , , , | Leave a comment

Pharmacological Treatments for Neuropsychiatric Symptoms in Alzheimer’s Disease (Journal of Neurology Neurosurgery and Psychiatry)

Summary This systematic review investigates the efficacy and safety of various pharmacological treatments for neuropsychiatric symptoms in Alzheimer’s Disease patients. It concludes that cholinesterase inhibitors (ChEIs) and atypical antipsychotics could improve neuropsychiatric symptoms in these patients, but with poor patient … Continue reading

Posted in Antipsychotics, Depression, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Pharmacological Treatments, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Systematic Review of Treatments to Prevent Cognitive Decline (CMAJ: Journal of the Canadian Medical Association)

Summary This systematic review examined the best 32 randomised controlled trials (RCTs) investigating treatments for cognitive decline, including drug treatments, hormone therapies, nutritional supplements, physical activity and cognitive exercises. The authors looked comprehensively at pharmacological treatments and non-pharmacological treatments in healthy … Continue reading

Posted in For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Combination Therapy with Cholinesterase Inhibitors and Memantine (Dementia and Geriatric Cognitive Disorders Extra)

Summary This systematic review investigates the efficacy and safety of combination therapy with N-methyl-D-aspartic acid antagonists (memantine) and cholinesterase inhibitors (ChEIs) for treatment of dementia, compared to monotherapy with either memantine or a ChEI. Combination therapy appears to offer statistically … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments, Systematic Reviews, Universal Interest | Tagged , , , , , , , , , , , , , , | Leave a comment