Tag Archives: Creutzfeldt-Jakob Disease (CJD)

Possible Future Treatment of CJD? (BBC News)

Summary University College London Hospitals NHS Foundation Trust (UCLH)’s National Prion Clinic has been granted the go-ahead to test the use of a man-made antibody treatment (PRN100), with a view to halting or slowing the progression of sporadic CJD. “We … Continue reading

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No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

Summary After a near-miss mini-epidemic of Variant Creutzfeldt-Jakob Disease (vCJD) in the 1990s, experts caution that: “It is essential that we do not become complacent and continue both surveillance and risk management strategies in both human and animal prion diseases”. … Continue reading

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Urine Test for Creutzfeldt-Jakob Disease (CJD)? (BBC News / MRC / JAMA Neurology / NEJM)

Summary It may one day be possible to use a non-invasive diagnostic urine test to discover whether or not patients have sporadic Creutzfeldt-Jakob Disease (sCJD). Full Text Link Reference A urine test for Creutzfeldt-Jakob Disease may be possible. London: Medical … Continue reading

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Early Diagnosis of Parkinson’s Disease and DLB Using CSF Biomarker? (BBC News / Annals of Clinical and Translational Neurology)

Summary Research at the University of Edinburgh indicates that test for synuclein, which measures how sticky this protein molecule has become (i.e. alpha-synuclein aggregation), might be the key to diagnosing accurately the early stages of both Parkinson’s Disease and Dementia … Continue reading

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Potential Risk of Alzheimer’s Disease Transmission (BBC News / NHS Choices / Nature / MRC)

Summary There may be a theoretical risk of Alzheimer’s Disease being transmissible during surgical procedures, in the manner of Creutzfeldt-Jakob disease (CJD). This hypothesis has arisen as a result of the examination of the brains of eight patients who had … Continue reading

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Severe, Persistent and Fatal Delirium (Dementia and Geriatric Cognitive Disorders Extra)

Summary Delirium is typically a transient syndrome, but this study concentrates on severe persistent and potentially fatal delirium. Just 15 cases are considered, involving diverse diagnoses including Alzheimer’s Disease, dementia with Lewy bodies, Creutzfeldt-Jakob disease and progressive supranuclear palsy. Full … Continue reading

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Minimising CJD and vCJD Transmission Risks in Healthcare and Community Settings (Department of Health)

Summary The Advisory Committee on Dangerous Pathogens’ Transmissible Spongiform Encephalopathy (ACDP TSE) Risk Management Subgroup has released updated guidance which aims to minimise the risks of transmission of CJD and vCJD in healthcare and other public settings. Full Text Link … Continue reading

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