Tag Archives: CSF Tau

Further Dementia Diagnostic Test Accuracy Systematic Review Protocols (Cochrane Database)

Summary This is an additional list of diagnostic testing-related protocols, further to the Cochrane Dementia and Cognitive Improvement Group (CDCIG) Diagnostic Test Accuracy (DTA) protocols and protocol templates listed earlier in Generic Protocol(s) for Diagnostic Test Accuracy Reviews in Dementia … Continue reading

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Recent Brain Research / Neurology-Related Systematic Reviews and Meta-Analyses

Summary Recent reviews and meta-analyses on neurology-related topics are listed below. Some of these articles may be available freely (according to local circumstances). A suitable Athens password, a journal subscription or payment for access are required to obtain the full-text … Continue reading

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Social Workers (mostly), International, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Concerning the Diagnostic Accuracy of Plasma and CSF Biomarkers (Cochrane Database)

Summary This systematic review investigates the diagnostic accuracy of blood plasma and CSF Aß levels for detecting patients with mild cognitive impairment (MCI) and who are likely to progress to Alzheimer’s Disease or other types of dementia. The accuracy of … Continue reading

Posted in Charitable Bodies, Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)

Summary A hypothetical model of the major biomarkers of Alzheimer’s Disease, published by the same authors in 2010, has been updated in the light of new evidence. Full Text Link Reference Jack, CR. Jr. Knopman, DS. [and] Jagust, WJ. [et … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Early Diagnosis of Alzheimer’s Disease Using Spinal Fluid? (NHS Choices / Cell Reports)

Summary A recent diagnostic study has investigated the possibility of diagnosing Alzheimer’s Disease, years before disease onset, using cerebrospinal fluid (CSF). The technique for identifying people with Alzheimer’s Disease would be based on detecting very small amounts of abnormal (misfolded) … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Biomarker Assessments in Alzheimer’s Disease Clinical Trials (Quintiles / Frontiers in Aging Neuroscience)

Summary Accurate and sensitive tools are required for the early detection / diagnosis of Alzheimer’s Disease, particularly to assist research. Alzheimer’s Disease clinical trials make increasing use of biomarkers, particularly neuroimaging markers and cerebrospinal fluid (CSF) biomarkers obtained via invasive … Continue reading

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Brain Scans Distinguish Between Dementia Types (BBC News / Neurology)

Summary Scientists at the University of Pennsylvania believe they may have discovered how to distinguish between different types of dementia without the need for invasive lumbar puncture tests to obtain cerebrospinal fluid (csf).  Alzheimer’s and frontotemporal dementia share similar features and symptoms and can … Continue reading

Posted in BBC News, Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment